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Kristen O'Connell
Kristen O'Connell
Associate Professor, The Jackson Laboratory
Dirección de correo verificada de jax.org - Página principal
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Targeting of ion channels to membrane microdomains: localization of KV channels to lipid rafts
JR Martens, K O'Connell, M Tamkun
Trends in pharmacological sciences 25 (1), 16-21, 2004
2162004
Leptin modulates the intrinsic excitability of AgRP/NPY neurons in the arcuate nucleus of the hypothalamus
SB Baver, K Hope, S Guyot, C Bjørbaek, C Kaczorowski, KMS O'Connell
Journal of Neuroscience 34 (16), 5486-5496, 2014
1982014
Harnessing genetic complexity to enhance translatability of Alzheimer’s disease mouse models: a path toward precision medicine
SM Neuner, SE Heuer, MJ Huentelman, KMS O’Connell, CC Kaczorowski
Neuron 101 (3), 399-411. e5, 2019
1752019
Localization-dependent activity of the Kv2. 1 delayed-rectifier K+ channel
KMS O'Connell, R Loftus, MM Tamkun
Proceedings of the National Academy of Sciences 107 (27), 12351-12356, 2010
1422010
Functional analysis of the R1086H malignant hyperthermia mutation in the DHPR reveals an unexpected influence of the III-IV loop on skeletal muscle EC coupling
RG Weiss, KMS O’Connell, BE Flucher, PD Allen, M Grabner, RT Dirksen
American Journal of Physiology-Cell Physiology 287 (4), C1094-C1102, 2004
1422004
Kv2. 1 potassium channels are retained within dynamic cell surface microdomains that are defined by a perimeter fence
KMS O'Connell, AS Rolig, JD Whitesell, MM Tamkun
Journal of Neuroscience 26 (38), 9609-9618, 2006
1412006
Targeting of voltage-gated potassium channel isoforms to distinct cell surface microdomains
KMS O'Connell, MM Tamkun
Journal of cell science 118 (10), 2155-2166, 2005
1412005
Gene-by-environment interactions in Alzheimer’s disease and Parkinson’s disease
AR Dunn, KMS O’Connell, CC Kaczorowski
Neuroscience & Biobehavioral Reviews 103, 73-80, 2019
1212019
Localization of ion channels to lipid Raft domains within the cardiovascular system
KMS O'Connell, JR Martens, MM Tamkun
Trends in cardiovascular medicine 14 (2), 37-42, 2004
1142004
A cytoskeletal-based perimeter fence selectively corrals a sub-population of cell surface Kv2. 1 channels
MM Tamkun, KMS O'connell, AS Rolig
Journal of cell science 120 (14), 2413-2423, 2007
1092007
The pore region of the skeletal muscle ryanodine receptor is a primary locus for excitation-contraction uncoupling in central core disease
G Avila, KMS O'Connell, RT Dirksen
The Journal of general physiology 121 (4), 277-286, 2003
902003
TRPC3 channels critically regulate hippocampal excitability and contextual fear memory
SM Neuner, LA Wilmott, KA Hope, B Hoffmann, JA Chong, J Abramowitz, ...
Behavioural brain research 281, 69-77, 2015
662015
Ca2+ release through ryanodine receptors regulates skeletal muscle L-type Ca2+ channel expression
G Avila, KMS O'Connell, LA Groom, RT Dirksen
Journal of Biological Chemistry 276 (21), 17732-17738, 2001
572001
Ca2+ release through ryanodine receptors regulates skeletal muscle L-type Ca2+ channel expression
G Avila, KMS O'Connell, LA Groom, RT Dirksen
Journal of Biological Chemistry 276 (21), 17732-17738, 2001
572001
Diet composition, not calorie intake, rapidly alters intrinsic excitability of hypothalamic AgRP/NPY neurons in mice
W Wei, K Pham, JW Gammons, D Sutherland, Y Liu, A Smith, ...
Scientific reports 5 (1), 16810, 2015
522015
Localization and mobility of the delayed-rectifer K+ channel Kv2.1 in adult cardiomyocytes
KMS O'Connell, JD Whitesell, MM Tamkun
American Journal of Physiology-Heart and Circulatory Physiology 294 (1 …, 2008
492008
Systems genetics identifies Hp1bp3 as a novel modulator of cognitive aging
SM Neuner, BP Garfinkel, LA Wilmott, BM Ignatowska-Jankowska, A Citri, ...
Neurobiology of aging 46, 58-67, 2016
372016
Calmodulin binding to the 3614–3643 region of RyR1 is not essential for excitation–contraction coupling in skeletal myotubes
KMS O'Connell, N Yamaguchi, G Meissner, RT Dirksen
The Journal of general physiology 120 (3), 337-347, 2002
372002
Translational approaches to understanding resilience to Alzheimer’s disease
SM Neuner, M Telpoukhovskaia, V Menon, KMS O’Connell, TJ Hohman, ...
Trends in neurosciences 45 (5), 369-383, 2022
332022
The C-terminus of neuronal Kv2. 1 channels is required for channel localization and targeting but not for NMDA-receptor-mediated regulation of channel function
SB Baver, KMS O’Connell
Neuroscience 217, 56-66, 2012
272012
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Artículos 1–20