Seguir
Lucy Kate Ladefoged
Lucy Kate Ladefoged
Postdoc, Computational Chemistry, Dept. of Biomedicine and Dept. of Chemistry, Aarhus University
Dirección de correo verificada de inano.au.dk
Título
Citado por
Citado por
Año
A direct interaction of cholesterol with the dopamine transporter prevents its out-to-inward transition
T Zeppelin, LK Ladefoged, S Sinning, X Periole, B Schiøtt
PLoS computational biology 14 (1), e1005907, 2018
842018
Monoamine transporters: insights from molecular dynamics simulations
J Grouleff, LK Ladefoged, H Koldsø, B Schiøtt
Frontiers in pharmacology 6, 159328, 2015
782015
Binding of the multimodal antidepressant drug vortioxetine to the human serotonin transporter
J Andersen, LK Ladefoged, D Wang, TNB Kristensen, B Bang-Andersen, ...
ACS chemical neuroscience 6 (11), 1892-1900, 2015
272015
Binding-Induced Fluorescence of Serotonin Transporter Ligands: A Spectroscopic and Structural Study of 4-(4-(Dimethylamino)phenyl)-1-methylpyridinium (APP+) and APP …
JN Wilson, LK Ladefoged, WM Babinchak, B Schiøtt
ACS chemical neuroscience 5 (4), 296-304, 2014
242014
Modeling and mutational analysis of the binding mode for the multimodal antidepressant drug vortioxetine to the human 5-HT3A receptor
LK Ladefoged, L Munro, AJ Pedersen, SCR Lummis, B Bang-Andersen, ...
Molecular Pharmacology 94 (6), 1421-1434, 2018
212018
Interrogating the molecular basis for substrate recognition in serotonin and dopamine transporters with high-affinity substrate-based bivalent ligands
J Andersen, LK Ladefoged, TNB Kristensen, L Munro, J Grouleff, ...
ACS chemical neuroscience 7 (10), 1406-1417, 2016
212016
Substrate and inhibitor binding to the serotonin transporter: Insights from computational, crystallographic, and functional studies
T Zeppelin, LK Ladefoged, S Sinning, B Schiøtt
Neuropharmacology 161, 107548, 2019
172019
A photoswitchable inhibitor of the human serotonin transporter
B Cheng, J Morstein, LK Ladefoged, JB Maesen, B Schiøtt, S Sinning, ...
ACS chemical neuroscience 11 (9), 1231-1237, 2020
152020
Conformational changes in the 5-HT3A receptor extracellular domain measured by Voltage-Clamp fluorometry
L Munro, LK Ladefoged, V Padmanathan, S Andersen, B Schiøtt, ...
Molecular Pharmacology 96 (6), 720-734, 2019
82019
Molecular modeling of neurological membrane proteins− from binding sites to synapses
LK Ladefoged, T Zeppelin, B Schiøtt
Neuroscience Letters 700, 38-49, 2019
42019
Divergent synthesis of new α-glucosidase inhibitors obtained through a vinyl Grignard-mediated carbocyclisation
IMB Knudsen, C Hedberg, LK Ladefoged, D Ide, A Brinkø, EZ Eikeland, ...
Organic & Biomolecular Chemistry 16 (34), 6250-6261, 2018
42018
Inhibitory effects of fluorinated benzenesulfonamides on insulin fibrillation
SHA Janvand, LK Ladefoged, A Zubrienė, A Sakalauskas, G Christiansen, ...
International journal of biological macromolecules 227, 590-600, 2023
32023
Beneficent and Maleficent Effects of Cations on Bufadienolide Binding to Na+,K+-ATPase
LK Ladefoged, B Schiøtt, NU Fedosova
Journal of Chemical Information and Modeling 61 (2), 976-986, 2021
32021
Binding and activation of serotonergic G-protein coupled receptors by the multimodal antidepressant vortioxetine
LK Ladefoged, R Koch, PC Biggin, B Schiøtt
ACS Chemical Neuroscience 13 (8), 1129-1142, 2022
12022
Geometry and water accessibility of the inhibitor binding site of Na+-pump: Pulse-and CW-EPR study
E Aloi, JH Guo, R Guzzi, RW Jiang, LK Ladefoged, D Marsh, M Esmann, ...
Biophysical Journal 120 (13), 2679-2690, 2021
12021
Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT3 receptors
U López-Sánchez, LJ Munro, LK Ladefoged, AJ Pedersen, CC Brun, ...
Nature Structural & Molecular Biology, 1-11, 2024
2024
Potentiation of drug toxicity through virus latency reversal promotes preferential elimination of HIV infected cells
TT Truong, M Hayn, CK Frich, LR Olari, LK Ladefoged, MTJ Olesen, ...
Advanced Therapeutics 5 (11), 2200113, 2022
2022
Molecular Insight into the Agonist Properties of the Multimodal Antidepressant Vortioxetine in Human 5-HT3A Receptors
LK Ladefoged, L Munro, AS Kristensen, B Schiøtt
Biophysical Journal 116 (3), 479a, 2019
2019
Computational modeling of the serotonergic synapse: Investigations of small molecule binding and effect
LK Ladefoged
2019
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–19