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Joshua S. Chappie
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The conserved KMN network constitutes the core microtubule-binding site of the kinetochore
IM Cheeseman, JS Chappie, EM Wilson-Kubalek, A Desai
Cell 127 (5), 983-997, 2006
11492006
Phylogenetic analysis and structural modeling of SARS-CoV-2 spike protein reveals an evolutionary distinct and proteolytically sensitive activation loop
JA Jaimes, NM André, JS Chappie, JK Millet, GR Whittaker
Journal of molecular biology 432 (10), 3309-3325, 2020
4972020
G domain dimerization controls dynamin's assembly-stimulated GTPase activity
JS Chappie, S Acharya, M Leonard, SL Schmid, F Dyda
Nature 465 (7297), 435-440, 2010
3392010
A pseudoatomic model of the dynamin polymer identifies a hydrolysis-dependent powerstroke
JS Chappie, JA Mears, S Fang, M Leonard, SL Schmid, RA Milligan, ...
Cell 147 (1), 209-222, 2011
2562011
The dynamin middle domain is critical for tetramerization and higher‐order self‐assembly
R Ramachandran, M Surka, JS Chappie, DM Fowler, TR Foss, BD Song, ...
The EMBO journal 26 (2), 559-566, 2007
2082007
Electrostatic tuning of ion conductance in potassium channels
CM Nimigean, JS Chappie, C Miller
Biochemistry 42 (31), 9263-9268, 2003
1442003
An intramolecular signaling element that modulates dynamin function in vitro and in vivo
JS Chappie, S Acharya, YW Liu, M Leonard, TJ Pucadyil, SL Schmid
Molecular biology of the cell 20 (15), 3561-3571, 2009
1132009
A dynamin mutant defines a superconstricted prefission state
AC Sundborger, S Fang, JA Heymann, P Ray, JS Chappie, JE Hinshaw
Cell reports 8 (3), 734-742, 2014
1032014
Building a fission machine–structural insights into dynamin assembly and activation
JS Chappie, F Dyda
Journal of cell science 126 (13), 2773-2784, 2013
782013
The structure of a eukaryotic nicotinic acid phosphoribosyltransferase reveals structural heterogeneity among type II PRTases
JS Chappie, JM Cànaves, GW Han, CL Rife, Q Xu, RC Stevens
Structure 13 (9), 1385-1396, 2005
462005
Endopeptidase regulation as a novel function of the Zur-dependent zinc starvation response
SG Murphy, L Alvarez, MC Adams, S Liu, JS Chappie, F Cava, T Dörr
MBio 10 (1), 10.1128/mbio. 02620-18, 2019
412019
Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage
CJ Schiltz, A Lee, EA Partlow, CJ Hosford, JS Chappie
Nucleic Acids Research 47 (17), 9448-9463, 2019
362019
The structural biology of the dynamin‐related proteins: New insights into a diverse, multitalented family
MGJ Ford, JS Chappie
Traffic 20 (10), 717-740, 2019
322019
Diffusible signal factors act through AraC-type transcriptional regulators as chemical cues to repress virulence of enteric pathogens
EM Bosire, CR Eade, CJ Schiltz, AJ Reid, J Troutman, JS Chappie, ...
Infection and immunity 88 (10), 10.1128/iai. 00226-20, 2020
262020
Cyclin N-terminal domain-containing-1 coordinates meiotic crossover formation with cell-cycle progression in a cyclin-independent manner
S Gray, ER Santiago, JS Chappie, PE Cohen
Cell reports 32 (1), 2020
202020
The full-length structure of Thermus scotoductus OLD defines the ATP hydrolysis properties and catalytic mechanism of Class 1 OLD family nucleases
CJ Schiltz, MC Adams, JS Chappie
Nucleic Acids Research 48 (5), 2762-2776, 2020
192020
A structural mechanism for phosphorylation-dependent inactivation of the AP2 complex
EA Partlow, RW Baker, GM Beacham, JS Chappie, AE Leschziner, ...
Elife 8, e50003, 2019
192019
The amino acid linker between the endonuclease and helicase domains of adeno-associated virus type 5 Rep plays a critical role in DNA-dependent oligomerization
JE Maggin, JA James, JS Chappie, F Dyda, AB Hickman
Journal of virology 86 (6), 3337-3346, 2012
182012
The structure of the Thermococcus gammatolerans McrB N-terminal domain reveals a new mode of substrate recognition and specificity among McrB homologs
CJ Hosford, AQ Bui, JS Chappie
Journal of Biological Chemistry 295 (3), 743-756, 2020
162020
Structures of the fungal dynamin-related protein Vps1 reveal a unique, open helical architecture
NV Varlakhanova, FJD Alvarez, TM Brady, BA Tornabene, CJ Hosford, ...
Journal of Cell Biology 217 (10), 3608-3624, 2018
152018
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