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Nicolas Locker
Nicolas Locker
University of Surrey
No hay ninguna dirección de correo electrónico verificada.
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mRNA circularization by METTL3–eIF3h enhances translation and promotes oncogenesis
J Choe, S Lin, W Zhang, Q Liu, L Wang, J Ramirez-Moya, P Du, W Kim, ...
Nature 561 (7724), 556-560, 2018
5842018
HCV and CSFV IRES domain II mediate eIF2 release during 80S ribosome assembly
N Locker, LE Easton, PJ Lukavsky
The EMBO journal 26 (3), 795-805, 2007
1852007
Flavivirus infection uncouples translation suppression from cellular stress responses
H Roth, V Magg, F Uch, P Mutz, P Klein, K Haneke, V Lohmann, ...
MBio 8 (1), 10.1128/mbio. 02150-16, 2017
1172017
Far upstream element binding protein 1 binds the internal ribosomal entry site of enterovirus 71 and enhances viral translation and viral growth
PN Huang, JY Lin, N Locker, YA Kung, CT Hung, JY Lin, HI Huang, ML Li, ...
Nucleic acids research 39 (22), 9633-9648, 2011
1012011
m6A RNA methylation, a new hallmark in virus-host interactions
M Brocard, A Ruggieri, N Locker
Journal of General Virology 98 (9), 2207-2214, 2017
982017
A conserved structure within the HIV gag open reading frame that controls translation initiation directly recruits the 40S subunit and eIF3
N Locker, N Chamond, B Sargueil
Nucleic acids research 39 (6), 2367-2377, 2011
912011
Structural features of the Seneca Valley virus internal ribosome entry site (IRES) element: a picornavirus with a pestivirus-like IRES
MM Willcocks, N Locker, Z Gomwalk, E Royall, M Bakhshesh, GJ Belsham, ...
Journal of virology 85 (9), 4452-4461, 2011
822011
Structure of eIF3b RNA recognition motif and its interaction with eIF3j: structural insights into the recruitment of eIF3b to the 40 S ribosomal subunit
L ElAntak, AG Tzakos, N Locker, PJ Lukavsky
Journal of Biological Chemistry 282 (11), 8165-8174, 2007
702007
Norovirus translation requires an interaction between the C terminus of the genome-linked viral protein VPg and eukaryotic translation initiation factor 4G
L Chung, D Bailey, EN Leen, EP Emmott, Y Chaudhry, LO Roberts, ...
Journal of Biological Chemistry 289 (31), 21738-21750, 2014
672014
Biochemical and NMR study on the competition between proteins SC35, SRp40, and heterogeneous nuclear ribonucleoprotein A1 at the HIV-1 Tat exon 2 splicing site
H Hallay, N Locker, L Ayadi, D Ropers, E Guittet, C Branlant
Journal of biological chemistry 281 (48), 37159-37174, 2006
662006
Translation initiation on mRNAs bound by nuclear cap-binding protein complex CBP80/20 requires interaction between CBP80/20-dependent translation initiation factor and …
J Choe, N Oh, S Park, YK Lee, OK Song, N Locker, SG Chi, YK Kim
Journal of Biological Chemistry 287 (22), 18500-18509, 2012
592012
Feline calicivirus infection disrupts assembly of cytoplasmic stress granules and induces G3BP1 cleavage
MN Humoud, N Doyle, E Royall, MM Willcocks, F Sorgeloos, ...
Journal of virology 90 (14), 6489-6501, 2016
582016
Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation
M Hosmillo, J Lu, MR McAllaster, JB Eaglesham, X Wang, E Emmott, ...
Elife 8, e46681, 2019
572019
Circularization of flavivirus genomic RNA inhibits de novo translation initiation
TJ Sanford, HV Mears, T Fajardo Jr, N Locker, TR Sweeney
Nucleic acids research 47 (18), 9789-9802, 2019
542019
Conserved functional domains and a novel tertiary interaction near the pseudoknot drive translational activity of hepatitis C virus and hepatitis C virus-like internal ribosome …
LE Easton, N Locker, PJ Lukavsky
Nucleic acids research 37 (16), 5537-5549, 2009
482009
Murine norovirus 1 (MNV1) replication induces translational control of the host by regulating eIF4E activity during infection
E Royall, N Doyle, A Abdul-Wahab, E Emmott, SJ Morley, I Goodfellow, ...
Journal of Biological Chemistry 290 (8), 4748-4758, 2015
472015
Norovirus-mediated modification of the translational landscape via virus and host-induced cleavage of translation initiation factors
E Emmott, F Sorgeloos, SL Caddy, S Vashist, S Sosnovtsev, R Lloyd, ...
Molecular & Cellular Proteomics 16 (4), S215-S229, 2017
452017
The different pathways of HIV genomic RNA translation
N Chamond, N Locker, B Sargueil
Biochemical Society transactions 38 (6), 1548-1552, 2010
442010
Norovirus infection results in eIF2α independent host translation shut-off and remodels the G3BP1 interactome evading stress granule formation
M Brocard, V Iadevaia, P Klein, B Hall, G Lewis, J Lu, J Burke, ...
PLoS pathogens 16 (1), e1008250, 2020
392020
Translational control during calicivirus infection
E Royall, N Locker
Viruses 8 (4), 104, 2016
382016
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