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Maria Jose Costa
Maria Jose Costa
Tallac Therapeutics
Dirección de correo verificada de tallactx.com
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Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E
AC Hsieh, M Costa, O Zollo, C Davis, ME Feldman, JR Testa, O Meyuhas, ...
Cancer cell 17 (3), 249-261, 2010
5342010
Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency
M Barna, A Pusic, O Zollo, M Costa, N Kondrashov, E Rego, PH Rao, ...
Nature 456 (7224), 971-975, 2008
5042008
Roles of hydrogen peroxide in thyroid physiology and disease
Y Song, N Driessens, M Costa, X De Deken, V Detours, B Corvilain, ...
The Journal of Clinical Endocrinology & Metabolism 92 (10), 3764-3773, 2007
2832007
Characterization of Cre recombinase activity for in vivo targeting of adipocyte precursor cells
KC Krueger, MJ Costa, H Du, BJ Feldman
Stem cell reports 3 (6), 1147-1158, 2014
1072014
Circadian rhythm gene period 3 is an inhibitor of the adipocyte cell fate
MJ Costa, AYL So, K Kaasik, KC Krueger, ML Pillsbury, YH Fu, LJ Ptacek, ...
Journal of biological chemistry 286 (11), 9063-9070, 2011
1052011
The circadian clock regulates adipogenesis by a Per3 crosstalk pathway to Klf15
A Aggarwal, MJ Costa, B Rivero-Gutiérrez, L Ji, SL Morgan, BJ Feldman
Cell reports 21 (9), 2367-2375, 2017
712017
A novel CXCR4 antagonist IgG1 antibody (PF-06747143) for the treatment of hematologic malignancies
SH Liu, Y Gu, B Pascual, Z Yan, M Hallin, C Zhang, C Fan, W Wang, ...
Blood advances 1 (15), 1088-1100, 2017
452017
Oncogenic mutations in the thyrotropin receptor of autonomously functioning thyroid nodules in the Japanese population
V Vanvooren, S Uchino, L Duprez, MJ Costa, J Vandekerckhove, J Parma, ...
European journal of endocrinology 147 (3), 287-291, 2002
452002
Role of caveolin-1 in thyroid phenotype, cell homeostasis, and hormone synthesis: in vivo study of caveolin-1 knockout mice
M Senou, MJ Costa, C Massart, M Thimmesch, C Khalifa, S Poncin, ...
American Journal of Physiology-Endocrinology and Metabolism 297 (2), E438-E451, 2009
432009
Immunohistochemical study of heat shock proteins 27, 60 and 70 in the normal human adrenal and in adrenal tumors with suppressed ACTH production
D Pignatelli, J Ferreira, P Soares, M José Costa, M Conceição Magalhães
Microscopy research and technique 61 (3), 315-323, 2003
432003
A glucocorticoid-and diet-responsive pathway toggles adipocyte precursor cell activity in vivo
JC Wong, KC Krueger, MJ Costa, A Aggarwal, H Du, TL McLaughlin, ...
Science signaling 9 (451), ra103-ra103, 2016
352016
Sphingolipid-cholesterol domains (lipid rafts) in normal human and dog thyroid follicular cells are not involved in thyrotropin receptor signaling
MJ Costa, Y Song, P Macours, C Massart, MC Many, S Costagliola, ...
Endocrinology 145 (3), 1464-1472, 2004
322004
Kinetics of thyrotropin-stimulating hormone (TSH) and thyroid-stimulating antibody binding and action on the TSH receptor in intact TSH receptor-expressing CHO cells
J Van Sande, MJ Costa, C Massart, S Swillens, S Costagliola, J Orgiazzi, ...
The Journal of Clinical Endocrinology & Metabolism 88 (11), 5366-5374, 2003
212003
Notch4 is required for tumor onset and perfusion
MJ Costa, X Wu, H Cuervo, R Srinivasan, SK Bechis, E Cheang, ...
Vascular cell 5, 1-10, 2013
202013
Optimal design, anti-tumour efficacy and tolerability of anti-CXCR4 antibody drug conjugates
MJ Costa, J Kudaravalli, JT Ma, WH Ho, K Delaria, C Holz, A Stauffer, ...
Scientific Reports 9 (1), 2443, 2019
182019
A mouse model for evaluation of efficacy and concomitant toxicity of anti-human CXCR4 therapeutics
MJ Costa, J Kudaravalli, WH Liu, J Stock, S Kong, SH Liu
PLoS One 13 (3), e0194688, 2018
122018
Using SRM-MS to quantify nuclear protein abundance differences between adipose tissue depots of insulin-resistant mice
A Ota, KM Kovary, OH Wu, R Ahrends, WJ Shen, MJ Costa, BJ Feldman, ...
Journal of lipid research 56 (5), 1068-1078, 2015
122015
Reciprocal negative regulation between thyrotropin/3′, 5′-cyclic adenosine monophosphate-mediated proliferation and caveolin-1 expression in human and murine thyrocytes
MJ Costa, M Senou, F Van Rode, J Ruf, M Capello, D Dequanter, ...
Molecular endocrinology 21 (4), 921-932, 2007
112007
Mutated E-cadherin: genomic and functional characterization in thyroid cells from the KAT family
A Sofia Rocha, O De Wever, S Moreira, MJ Costa, J Vandekerckhove, ...
Thyroid 14 (11), 902-909, 2004
72004
IO-108, A fully human therapeutic antibody blocking the myeloid checkpoint LILRB2/ILT4, promotes innate and adaptive anti-cancer immunity in preclinical studies
JT Ma, X Liu, R Stafford, K McCutcheon, H Chen, T Huang, H Tian, ...
Cancer Res 82 (12_suppl), 601-601, 2022
32022
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