| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10685 | 2021 |
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| Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis C Zhu, KJ Kim, X Wang, A Bartolome, M Salomao, P Dongiovanni, ... Science translational medicine 10 (468), eaat0344, 2018 | 179 | 2018 |
| Pancreatic β-cell failure mediated by mTORC1 hyperactivity and autophagic impairment A Bartolomé, M Kimura-Koyanagi, SI Asahara, C Guillén, H Inoue, ... Diabetes 63 (9), 2996-3008, 2014 | 126 | 2014 |
| Autophagy plays a protective role in endoplasmic reticulum stress-mediated pancreatic β cell death A Bartolome, C Guillen, M Benito Autophagy 8 (12), 1757-1768, 2012 | 122 | 2012 |
| MTORC1 regulates both general autophagy and mitophagy induction after oxidative phosphorylation uncoupling A Bartolomé, A García-Aguilar, SI Asahara, Y Kido, C Guillén, UB Pajvani, ... Molecular and cellular biology 37 (23), e00441-17, 2017 | 113 | 2017 |
| Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosis J Yu, C Zhu, X Wang, KJ Kim, A Bartolome, P Dongiovanni, KP Yates, ... Science translational medicine 13 (599), eabe1692, 2021 | 62 | 2021 |
| Paternal allelic mutation at the Kcnq1 locus reduces pancreatic β-cell mass by epigenetic modification of Cdkn1c S Asahara, H Etoh, H Inoue, K Teruyama, Y Shibutani, Y Ihara, Y Kawada, ... Proceedings of the National Academy of Sciences 112 (27), 8332-8337, 2015 | 59 | 2015 |
| Evidence for a non-leptin system that defends against weight gain in overfeeding Y Ravussin, E Edwin, M Gallop, L Xu, A Bartolomé, MJ Kraakman, ... Cell metabolism 28 (2), 289-299. e5, 2018 | 57 | 2018 |
| DPP4 inhibitor vildagliptin preserves-cell mass through amelioration of endoplasmic reticulum stress in C/EBPB transgenic mice S Shimizu, T Hosooka, T Matsuda, S Asahara, M Koyanagi-Kimura, ... Journal of molecular endocrinology 49 (2), 125, 2012 | 54 | 2012 |
| Notch signaling dynamically regulates adult β cell proliferation and maturity A Bartolome, C Zhu, L Sussel, UB Pajvani The Journal of clinical investigation 129 (1), 268-280, 2019 | 50 | 2019 |
| Autophagy impairment aggravates the inhibitory effects of high glucose on osteoblast viability and function A Bartolome, A Lopez-Herradon, S Portal-Nunez, A Garcia-Aguilar, ... Biochemical Journal 455 (3), 329-337, 2013 | 46 | 2013 |
| Role of the TSC1-TSC2 complex in the integration of insulin and glucose signaling involved in pancreatic β-cell proliferation A Bartolomé, C Guillén, M Benito Endocrinology 151 (7), 3084-3094, 2010 | 46 | 2010 |
| Notch activity characterizes a common hepatocellular carcinoma subtype with unique molecular and clinicopathologic features C Zhu, YJ Ho, MA Salomao, DH Dapito, A Bartolome, RF Schwabe, ... Journal of hepatology 74 (3), 613-626, 2021 | 39 | 2021 |
| TSC2 N-terminal lysine acetylation status affects to its stability modulating mTORC1 signaling and autophagy A García-Aguilar, C Guillén, M Nellist, A Bartolomé, M Benito Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (11), 2658-2667, 2016 | 38 | 2016 |
| Role of the mammalian target of rapamycin (mTOR) complexes in pancreatic β-cell mass regulation A Bartolome, C Guillén Vitamins & Hormones 95, 425-469, 2014 | 32 | 2014 |
| Histone deacetylase regulates insulin signaling via two pathways in pancreatic β cells Y Kawada, S Asahara, Y Sugiura, A Sato, A Furubayashi, M Kawamura, ... PLoS One 12 (9), e0184435, 2017 | 24 | 2017 |
| Biphasic effect of insulin on beta cell apoptosis depending on glucose deprivation C Guillen, A Bartolomé, C Nevado, M Benito FEBS letters 582 (28), 3855-3860, 2008 | 23 | 2008 |
| Regulation of pancreatic β cell mass by cross-interaction between CCAAT enhancer binding protein β induced by endoplasmic reticulum stress and AMP-activated protein kinase activity T Matsuda, H Takahashi, Y Mieda, S Shimizu, T Kawamoto, Y Matsuura, ... PLoS One 10 (6), e0130757, 2015 | 22 | 2015 |
| GCN2 regulates pancreatic β cell mass by sensing intracellular amino acid levels A Kanno, S Asahara, A Furubayashi, K Masuda, R Yoshitomi, E Suzuki, ... JCI insight 5 (9), 2020 | 18 | 2020 |
