Gavin Barnard
Gavin Barnard
Group Leader, Eli Lilly
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The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL
PJ Emmerson, F Wang, Y Du, Q Liu, RT Pickard, MD Gonciarz, T Coskun, ...
Nature medicine 23 (10), 1215, 2017
Integrated recombinant protein expression and purification platform based on Ralstonia eutropha
GC Barnard, JD McCool, DW Wood, TU Gerngross
Applied and environmental microbiology 71 (10), 5735-5742, 2005
High level recombinant protein expression in Ralstonia eutropha using T7 RNA polymerase based amplification
GC Barnard, GE Henderson, S Srinivasan, TU Gerngross
Protein expression and purification 38 (2), 264-271, 2004
High-throughput screening and selection of yeast cell lines expressing monoclonal antibodies
GC Barnard, AR Kull, NS Sharkey, SS Shaikh, AM Rittenhour, I Burnina, ...
Journal of industrial microbiology & biotechnology 37 (9), 961-971, 2010
A novel high-cell-density protein expression system based on Ralstonia eutropha
S Srinivasan, GC Barnard, TU Gerngross
Applied and Environmental Microbiology 68 (12), 5925-5932, 2002
Optimization of erythropoietin production with controlled glycosylation-PEGylated erythropoietin produced in glycoengineered Pichia pastoris
JH Nett, S Gomathinayagam, SR Hamilton, B Gong, RC Davidson, M Du, ...
Journal of biotechnology 157 (1), 198-206, 2012
A high cell density transient transfection system for therapeutic protein expression based on a CHO GS‐knockout cell line: process development and product quality assessment
Y Rajendra, MD Hougland, R Alam, TA Morehead, GC Barnard
Biotechnology and Bioengineering 112 (5), 977-986, 2015
Production of recombinant proteins using multiple‐copy gene integration in high‐cell‐density fermentations of Ralstonia eutropha
S Srinivasan, GC Barnard, TU Gerngross
Biotechnology and bioengineering 84 (1), 114-120, 2003
Generation of stable Chinese hamster ovary pools yielding antibody titers of up to 7.6 g/L using the piggyBac transposon system
Y Rajendra, RB Peery, GC Barnard
Biotechnology progress 32 (5), 1301-1307, 2016
High‐throughput mAb expression and purification platform based on transient CHO
GC Barnard, MD Hougland, Y Rajendra
Biotechnology progress 31 (1), 239-247, 2015
Production and purification of self-assembling peptides in Ralstonia eutropha
DC Reed, GC Barnard, EB Anderson, LT Klein, TU Gerngross
Protein expression and purification 46 (2), 179-188, 2006
Evaluation of piggyBac‐mediated CHO pools to enable material generation to support GLP toxicology studies
Y Rajendra, S Balasubramanian, NA McCracken, DL Norris, Z Lian, ...
Biotechnology progress 33 (6), 1436-1448, 2017
Bioreactor scale up and protein product quality characterization of piggyBac transposon derived CHO pools
Y Rajendra, S Balasubramanian, RB Peery, JR Swartling, NA McCracken, ...
Biotechnology Progress 33 (2), 534-540, 2017
Generation of High Expressing Chinese Hamster Ovary Cell Pools Using the Leap‐In Transposon System
S Balasubramanian, RB Peery, J Minshull, M Lee, R White, RM Kelly, ...
Biotechnology journal 13 (10), 1700748, 2018
Transient and stable CHO expression, purification and characterization of novel hetero‐dimeric bispecific I g G antibodies
Y Rajendra, RB Peery, MD Hougland, GC Barnard, X Wu, JR Fitchett, ...
Biotechnology Progress 33 (2), 469-477, 2017
Transcriptional and post-transcriptional targeting for enhanced transient gene expression in CHO cells
Y Rajendra, MD Hougland, MG Schmitt, GC Barnard
Biotechnology letters 37 (12), 2379-2386, 2015
Polymer‐mediated flocculation of transient CHO cultures as a simple, high throughput method to facilitate antibody discovery
MG Schmitt, Y Rajendra, MD Hougland, JS Boyles, GC Barnard
Biotechnology Progress 33 (5), 1393-1400, 2017
High titer transient gene expression platform based on GS CHO cell line–rapid protein expression tool for preclinical drug development
Y Rajendra, G Barnard
Development of a high cell density transient CHO platform yielding mAb titers greater than 2 g/L in only 7 days
MG Schmitt, RN White, GC Barnard
Biotechnology Progress, e3047, 2020
Transposon-Mediated Gene Integration – The Future Of Stable CHO Cell Line Development?
G Barnard
25th ESACT Meeting (2017), 2017
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