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Gavin Barnard
Gavin Barnard
Senior Director, Genentech
Verified email at gene.com
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Year
The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL
PJ Emmerson, F Wang, Y Du, Q Liu, RT Pickard, MD Gonciarz, T Coskun, ...
Nature medicine 23 (10), 1215-1219, 2017
4972017
High-throughput screening and selection of yeast cell lines expressing monoclonal antibodies
GC Barnard, AR Kull, NS Sharkey, SS Shaikh, AM Rittenhour, I Burnina, ...
Journal of Industrial Microbiology and Biotechnology 37 (9), 961-971, 2010
882010
Integrated Recombinant Protein Expression and Purification Platform Based on Ralstonia eutropha
GC Barnard, JD McCool, DW Wood, TU Gerngross
Applied and environmental microbiology 71 (10), 5735-5742, 2005
842005
High level recombinant protein expression in Ralstonia eutropha using T7 RNA polymerase based amplification
GC Barnard, GE Henderson, S Srinivasan, TU Gerngross
Protein expression and purification 38 (2), 264-271, 2004
762004
A high cell density transient transfection system for therapeutic protein expression based on a CHO GS‐knockout cell line: process development and product quality assessment
Y Rajendra, MD Hougland, R Alam, TA Morehead, GC Barnard
Biotechnology and bioengineering 112 (5), 977-986, 2015
662015
A Novel High-Cell-Density Protein Expression System Based on Ralstonia eutropha
S Srinivasan, GC Barnard, TU Gerngross
Applied and Environmental Microbiology 68 (12), 5925-5932, 2002
572002
Optimization of erythropoietin production with controlled glycosylation-PEGylated erythropoietin produced in glycoengineered Pichia pastoris
JH Nett, S Gomathinayagam, SR Hamilton, B Gong, RC Davidson, M Du, ...
Journal of biotechnology 157 (1), 198-206, 2012
472012
Production of recombinant proteins using multiple‐copy gene integration in high‐cell‐density fermentations of Ralstonia eutropha
S Srinivasan, GC Barnard, TU Gerngross
Biotechnology and bioengineering 84 (1), 114-120, 2003
422003
Generation of stable Chinese hamster ovary pools yielding antibody titers of up to 7.6 g/L using the piggyBac transposon system
Y Rajendra, RB Peery, GC Barnard
Biotechnology progress 32 (5), 1301-1307, 2016
332016
High‐throughput mAb expression and purification platform based on transient CHO
GC Barnard, MD Hougland, Y Rajendra
Biotechnology progress 31 (1), 239-247, 2015
312015
Evaluation of piggyBac‐mediated CHO pools to enable material generation to support GLP toxicology studies
Y Rajendra, S Balasubramanian, NA McCracken, DL Norris, Z Lian, ...
Biotechnology Progress 33 (6), 1436-1448, 2017
262017
Generation of high expressing Chinese hamster ovary cell pools using the Leap‐In transposon system
S Balasubramanian, RB Peery, J Minshull, M Lee, R White, RM Kelly, ...
Biotechnology Journal 13 (10), 1700748, 2018
242018
Bioreactor scale up and protein product quality characterization of piggyBac transposon derived CHO pools
Y Rajendra, S Balasubramanian, RB Peery, JR Swartling, NA McCracken, ...
Biotechnology Progress 33 (2), 534-540, 2017
242017
Transient and stable CHO expression, purification and characterization of novel hetero‐dimeric bispecific I g G antibodies
Y Rajendra, RB Peery, MD Hougland, GC Barnard, X Wu, JR Fitchett, ...
Biotechnology Progress 33 (2), 469-477, 2017
192017
Transcriptional and post-transcriptional targeting for enhanced transient gene expression in CHO cells
Y Rajendra, MD Hougland, MG Schmitt, GC Barnard
Biotechnology letters 37, 2379-2386, 2015
182015
Production and purification of self-assembling peptides in Ralstonia eutropha
DC Reed, GC Barnard, EB Anderson, LT Klein, TU Gerngross
Protein expression and purification 46 (2), 179-188, 2006
172006
Development of a high cell density transient CHO platform yielding mAb titers greater than 2 g/L in only 7 days
MG Schmitt, RN White, GC Barnard
Biotechnology progress 36 (6), e3047, 2020
142020
Polymer‐mediated flocculation of transient CHO cultures as a simple, high throughput method to facilitate antibody discovery
MG Schmitt, Y Rajendra, MD Hougland, JS Boyles, GC Barnard
Biotechnology Progress 33 (5), 1393-1400, 2017
62017
Expressing antigen binding fragments with high titers in a targeted integration CHO host by optimizing expression vector gene copy numbers and position: A case study
D Tang, J Gunson, E Tran, C Lam, A Shen, B Snedecor, G Barnard, ...
Biotechnology Progress 38 (6), e3290, 2022
22022
High titer transient gene expression platform based on GS CHO cell line–rapid protein expression tool for preclinical drug development
Y Rajendra, G Barnard
12016
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