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Thanh Nguyen Le
Thanh Nguyen Le
Head of department of Medicinal Chemistry, Institute of Marine Biochemistry, Vietnam
Dirección de correo verificada de imbc.vast.vn - Página principal
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A Versatile Total Synthesis of Benzo[c]phenanthridine and Protoberberine Alkaloids Using Lithiated Toluamide−Benzonitrile Cycloaddition
TN Le, SG Gang, WJ Cho
The Journal of Organic Chemistry 69 (8), 2768-2772, 2004
942004
Molecular modeling of 3-arylisoquinoline antitumor agents active against A-549. A comparative molecular field analysis study
WJ Cho, EK Kim, IY Park, EY Jeong, TS Kim, TN Le, DD Kim, ES Lee
Bioorganic & medicinal chemistry 10 (9), 2953-2961, 2002
692002
Synthesis of new 3-arylisoquinolinamines: effect on topoisomerase I inhibition and cytotoxicity
WJ Cho, SY Min, TN Le, TS Kim
Bioorganic & medicinal chemistry letters 13 (24), 4451-4454, 2003
632003
Artemisinin analogues as potent inhibitors of in vitro hepatitis C virus replication
S Obeid, J Alen, VH Nguyen, VC Pham, P Meuleman, C Pannecouque, ...
PLoS One 8 (12), e81783, 2013
622013
Phytochemical analysis of Vietnamese propolis produced by the stingless bee Lisotrigona cacciae
VB Kristina Georgieva, Milena Popova , Lyudmila Dimitrova, Boryana Trusheva ...
Plos One, 2019
572019
An efficient synthesis of chiral phosphinyl oxide pyrrolidines and their application to asymmetric direct aldol reactions
XW Liu, TN Le, Y Lu, Y Xiao, J Ma, X Li
Organic & Biomolecular Chemistry 6 (21), 3997-4003, 2008
562008
Ketorolac amide prodrugs for transdermal delivery: stability and in vitro rat skin permeation studies
BY Kim, HJ Doh, TN Le, WJ Cho, CS Yong, HG Choi, JS Kim, CH Lee, ...
International journal of pharmaceutics 293 (1-2), 193-202, 2005
542005
A facile synthesis of benzo [c] phenanthridine alkaloids: oxynitidine and oxysanguinarine using lithiated toluamide–benzonitrile cycloaddition
TN Le, SG Gang, WJ Cho
Tetrahedron letters 45 (13), 2763-2766, 2004
502004
Convenient synthesis of indeno [1, 2-c] isoquinolines as constrained forms of 3-arylisoquinolines and docking study of a topoisomerase I inhibitor into DNA–topoisomerase I complex
HTM Van, QM Le, KY Lee, ES Lee, Y Kwon, TS Kim, TN Le, SH Lee, ...
Bioorganic & medicinal chemistry letters 17 (21), 5763-5767, 2007
422007
Synthesis, in vitro and in vivo evaluation of 3-arylisoquinolinamines as potent antitumor agents
SH Yang, HTM Van, TN Le, DB Khadka, SH Cho, KT Lee, HJ Chung, ...
Bioorganic & medicinal chemistry letters 20 (17), 5277-5281, 2010
312010
Inhibitory effect on human platelet aggregation and coagulation and antioxidant activity of C. edulis Ker Gawl rhizome and its secondary metabolites
TMH Nguyen, HL Le, TT Ha, BH Bui, NT Le, TVA Nguyen
Journal of Ethnopharmacology 263, 113136, 2020
292020
Development of 3-aryl-1-isoquinolinamines as potent antitumor agents based on CoMFA
SH Yang, HTM Van, TN Le, DB Khadka, SH Cho, KT Lee, ES Lee, YB Lee, ...
European journal of medicinal chemistry 45 (11), 5493-5497, 2010
272010
Modification of 3-arylisoquinolines into 3, 4-diarylisoquinolines and assessment of their cytotoxicity and topoisomerase inhibition
DB Khadka, H Woo, SH Yang, C Zhao, Y Jin, TN Le, Y Kwon, WJ Cho
European Journal of Medicinal Chemistry 92, 583-607, 2015
262015
Phase‐Transfer‐Catalyzed Asymmetric Synthesis of 1, 1‐Disubstituted Tetrahydroisoquinolines
S Shirakawa, K Liu, H Ito, TN Le, K Maruoka
Advanced Synthesis & Catalysis 353 (14‐15), 2614-2618, 2011
252011
Total synthesis of oxyfagaronine, phenolic benzo [c] phenanthridine and general synthetic way of 2, 3, 7, 8-and 2, 3, 8, 9-tetrasubstituted benzo [c] phenanthridine alkaloids
TN Le, WJ Cho
Chemical and pharmaceutical bulletin 54 (4), 476-480, 2006
252006
Substituted 2-arylquinazolinones: Design, synthesis, and evaluation of cytotoxicity and inhibition of topoisomerases
WJC Daulat Bikram Khadka, Giap Huu Tran, Somin Shin, Hang Thi Minh Nguyen ...
European Journal of Medicinal Chemistry 103, 69-79, 2015
212015
New flavonoid and pentacyclic triterpene from Sesamum indicum leaves
LNT Nguyen Tien Dat, Nguyen Hai Dang
Natural Product Research 30 (3), 311-315, 2016
202016
Design and synthesis of 4-amino-2-phenylquinazolines as novel topoisomerase I inhibitors with molecular modeling
TN Le, SH Yang, DB Khadka, HTM Van, SH Cho, Y Kwon, ES Lee, ...
Bioorganic & medicinal chemistry 19 (14), 4399-4404, 2011
192011
Novel synthesis of the natural protoberberine alkaloids: Oxypalmatine and oxypseudopalmatine
TN Le, W Cho
BULLETIN-KOREAN CHEMICAL SOCIETY 28 (5), 763, 2007
192007
Synthesis of 11-aza-artemisinin derivatives using the Ugi reaction and an evaluation of their antimalarial activity
TN Le, WMD Borggraeve, P Grellier, VC Pham, W Dehaen, VH Nguyen
Tetrahedron Letters, 2014
182014
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Artículos 1–20