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Julio Santos Reboucas
Julio Santos Reboucas
Verified email at quimica.ufpb.br
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Year
Superoxide dismutase mimics: chemistry, pharmacology, and therapeutic potential
I Batinić-Haberle, JS Rebouças, I Spasojević
Antioxidants & redox signaling 13 (6), 877-918, 2010
5802010
Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two different models of oxidative stress …
I Batinić-Haberle, S Cuzzocrea, JS Rebouças, G Ferrer-Sueta, E Mazzon, ...
Free radical biology & medicine 46 (2), 192, 2009
1602009
Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics
I Batinic-Haberle, Z Rajic, A Tovmasyan, JS Reboucas, X Ye, KW Leong, ...
Free Radical Biology and Medicine 51 (5), 1035-1053, 2011
1542011
Early and late administration of MnTE-2-PyP5+ in mitigation and treatment of radiation-induced lung damage
B Gauter-Fleckenstein, K Fleckenstein, K Owzar, C Jiang, JS Rebouças, ...
Free Radical Biology and Medicine 48 (8), 1034-1043, 2010
1272010
Design and synthesis of manganese porphyrins with tailored lipophilicity: investigation of redox properties and superoxide dismutase activity
D Lahaye, K Muthukumaran, CH Hung, D Gryko, JS Rebouças, ...
Bioorganic & medicinal chemistry 15 (22), 7066-7086, 2007
1212007
Pure manganese (III) 5, 10, 15, 20-tetrakis (4-benzoic acid) porphyrin (MnTBAP) is not a superoxide dismutase mimic in aqueous systems: a case of structure–activity …
JS Rebouças, I Spasojević, I Batinić-Haberle
JBIC Journal of Biological Inorganic Chemistry 13, 289-302, 2008
1042008
Electrostatic Contribution in the Catalysis of O 2· _ Dismutation by Superoxide Dismutase Mimics: MnIIITE-2-PyP5+ VERSUSMnIIIBr8T-2-PyP+
I Spasojevic, I Batinic-Haberle, JS Rebouças, YM Idemori, I Fridovich
Journal of Biological Chemistry 278 (9), 6831-6837, 2003
912003
A comprehensive evaluation of catalase-like activity of different classes of redox-active therapeutics
A Tovmasyan, CGC Maia, T Weitner, S Carballal, RS Sampaio, D Lieb, ...
Free Radical Biology and Medicine 86, 308-321, 2015
882015
Pharmacokinetics of the potent redox-modulating manganese porphyrin, MnTE-2-PyP5+, in plasma and major organs of B6C3F1 mice
I Spasojević, Y Chen, TJ Noel, P Fan, L Zhang, JS Rebouças, DKS Clair, ...
Free Radical Biology and Medicine 45 (7), 943-949, 2008
792008
Lipophilicity of potent porphyrin-based antioxidants: comparison of ortho and meta isomers of Mn (III) N-alkylpyridylporphyrins
I Kos, JS Rebouças, G DeFreitas-Silva, D Salvemini, Z Vujaskovic, ...
Free Radical Biology and Medicine 47 (1), 72-78, 2009
772009
Partially and fully β-brominated Mn-porphyrins in P450 biomimetic systems: effects of the degree of bromination on electrochemical and catalytic properties
E Do Nascimento, GF Silva, FA Caetano, MAM Fernandes, DC da Silva, ...
Journal of inorganic biochemistry 99 (5), 1193-1204, 2005
772005
Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia–telangiectasia cells
JM Pollard, JS Reboucas, A Durazo, I Kos, F Fike, M Panni, EB Gralla, ...
Free Radical Biology and Medicine 47 (3), 250-260, 2009
752009
Anticancer therapeutic potential of Mn porphyrin/ascorbate system
A Tovmasyan, RS Sampaio, MK Boss, JC Bueno-Janice, BH Bader, ...
Free Radical Biology and Medicine 89, 1231-1247, 2015
742015
Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology
A Tovmasyan, T Weitner, H Sheng, MM Lu, Z Rajic, DS Warner, ...
Inorganic chemistry 52 (10), 5677-5691, 2013
742013
Impact of electrostatics in redox modulation of oxidative stress by Mn porphyrins: protection of SOD-deficient Escherichia coli via alternative mechanism where Mn porphyrin …
JS Rebouças, G DeFreitas-Silva, I Spasojević, YM Idemori, L Benov, ...
Free Radical Biology and Medicine 45 (2), 201-210, 2008
712008
Simple biological systems for assessing the activity of superoxide dismutase mimics
A Tovmasyan, JS Reboucas, L Benov
Antioxidants & Redox Signaling 20 (15), 2416-2436, 2014
672014
SOD-like activity of Mn (II) β-octabromo-meso-tetrakis (N-methylpyridinium-3-yl) porphyrin equals that of the enzyme itself
G DeFreitas-Silva, JS Rebouças, I Spasojević, L Benov, YM Idemori, ...
Archives of biochemistry and biophysics 477 (1), 105-112, 2008
632008
Comprehensive pharmacokinetic studies and oral bioavailability of two Mn porphyrin-based SOD mimics, MnTE-2-PyP5+ and MnTnHex-2-PyP5+
T Weitner, I Kos, H Sheng, A Tovmasyan, JS Reboucas, P Fan, ...
Free Radical Biology and Medicine 58, 73-80, 2013
612013
Spectral, electrochemical, and catalytic properties of a homologous series of manganese porphyrins as cytochrome P450 model: the effect of the degree of β-bromination
DC da Silva, G DeFreitas-Silva, E do Nascimento, JS Rebouças, ...
Journal of inorganic biochemistry 102 (10), 1932-1941, 2008
612008
Quality of potent Mn porphyrin-based SOD mimics and peroxynitrite scavengers for pre-clinical mechanistic/therapeutic purposes
JS Rebouças, I Spasojević, I Batinić-Haberle
Journal of pharmaceutical and biomedical analysis 48 (3), 1046-1049, 2008
602008
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