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Pedro P. Rocha
Pedro P. Rocha
Tenure-track Investigator NIH / NICHD
Dirección de correo verificada de nih.gov - Página principal
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CTCF establishes discrete functional chromatin domains at the Hox clusters during differentiation
V Narendra, PP Rocha, D An, R Raviram, JA Skok, EO Mazzoni, ...
Science 347 (6225), 1017-1021, 2015
5962015
Capturing the onset of PRC2-mediated repressive domain formation
O Oksuz, V Narendra, CH Lee, N Descostes, G LeRoy, R Raviram, ...
Molecular cell 70 (6), 1149-1162. e5, 2018
2362018
Med12 is essential for early mouse development and for canonical Wnt and Wnt/PCP signaling
PP Rocha, M Scholze, W Bleiß, H Schrewe
Development 137 (16), 2723-2731, 2010
1712010
Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms
J Mullenders, B Aranda-Orgilles, P Lhoumaud, M Keller, J Pae, K Wang, ...
Journal of Experimental Medicine 212 (11), 1833-1850, 2015
1682015
CRISPR-dCas9 and sgRNA scaffolds enable dual-colour live imaging of satellite sequences and repeat-enriched individual loci
Y Fu, PP Rocha, VM Luo, R Raviram, Y Deng, EO Mazzoni, JA Skok
Nature communications 7 (1), 11707, 2016
1542016
MED12 regulates HSC-specific enhancers independently of mediator kinase activity to control hematopoiesis
B Aranda-Orgilles, R Saldaña-Meyer, E Wang, E Trompouki, A Fassl, ...
Cell stem cell 19 (6), 784-799, 2016
1132016
Low-grade astrocytoma mutations in IDH1, P53, and ATRX cooperate to block differentiation of human neural stem cells via repression of SOX2
AS Modrek, D Golub, T Khan, D Bready, J Prado, C Bowman, J Deng, ...
Cell reports 21 (5), 1267-1280, 2017
942017
4C-ker: A Method to Reproducibly Identify Genome-Wide Interactions Captured by 4C-Seq Experiments
JAS Ramya Raviram, Pedro P. Rocha, Christian L. Müller, Emily R. Miraldi ...
Plos Computational Biology, 2016
932016
Close proximity to Igh is a contributing factor to AID-mediated translocations
PP Rocha, M Micsinai, JHR Kim, SL Hewitt, PP Souza, T Trimarchi, ...
Molecular cell 47 (6), 873-885, 2012
702012
Lack of functional and expression homology between human and mouse aldo-keto reductase 1C enzymes: implications for modelling human cancers
P Veliça, NJ Davies, PP Rocha, H Schrewe, JP Ride, CM Bunce
Molecular cancer 8, 1-12, 2009
682009
Breaking TADs: insights into hierarchical genome organization
PP Rocha, R Raviram, R Bonneau, JA Skok
Epigenomics 7 (4), 523-526, 2015
612015
Enhancer–promoter interactions can bypass CTCF-mediated boundaries and contribute to phenotypic robustness
S Chakraborty, N Kopitchinski, Z Zuo, A Eraso, P Awasthi, R Chari, A Mitra, ...
Nature genetics 55 (2), 280-290, 2023
53*2023
Identification of multi-loci hubs from 4C-seq demonstrates the functional importance of simultaneous interactions
T Jiang, R Raviram, V Snetkova, PP Rocha, C Proudhon, S Badri, ...
Nucleic acids research 44 (18), 8714-8725, 2016
502016
Analysis of 3D genomic interactions identifies candidate host genes that transposable elements potentially regulate
R Raviram, PP Rocha, VM Luo, E Swanzey, ER Miraldi, EB Chuong, ...
Genome biology 19, 1-19, 2018
412018
Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination
AS Thomas-Claudepierre, I Robert, PP Rocha, R Raviram, E Schiavo, ...
Journal of Experimental Medicine 213 (3), 303-312, 2016
382016
Wolf-Hirschhorn syndrome candidate 1 is necessary for correct hematopoietic and B cell development
E Campos-Sanchez, N Deleyto-Seldas, V Dominguez, ...
Cell reports 19 (8), 1586-1601, 2017
352017
A damage-independent role for 53BP1 that impacts break order and Igh architecture during class switch recombination
PP Rocha, R Raviram, Y Fu, JH Kim, VM Luo, A Aljoufi, E Swanzey, ...
Cell reports 16 (1), 48-55, 2016
352016
GATA3-Controlled Nucleosome Eviction Drives MYC Enhancer Activity in T-cell Development and Leukemia
L Belver, AY Yang, R Albero, D Herranz, FG Brundu, SA Quinn, ...
Cancer discovery 9 (12), 1774-1791, 2019
322019
Alu insertion variants alter gene transcript levels
LM Payer, JP Steranka, MS Kryatova, G Grillo, M Lupien, PP Rocha, ...
Genome research 31 (12), 2236-2248, 2021
272021
Linkage-specific deubiquitylation by OTUD5 defines an embryonic pathway intolerant to genomic variation
DB Beck, MA Basar, AJ Asmar, JJ Thompson, H Oda, DT Uehara, K Saida, ...
Science advances 7 (4), eabe2116, 2021
262021
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