| Hippocampal Lewy pathology and cholinergic dysfunction are associated with dementia in Parkinson’s disease H Hall, S Reyes, N Landeck, C Bye, G Leanza, K Double, L Thompson, ... Brain 137 (9), 2493-2508, 2014 | 301 | 2014 |
| Boosting chaperone-mediated autophagy in vivo mitigates α-synuclein-induced neurodegeneration M Xilouri, OR Brekk, N Landeck, PM Pitychoutis, T Papasilekas, ... Brain 136 (7), 2130-2146, 2013 | 209 | 2013 |
| LRRK2 mediates tubulation and vesicle sorting from lysosomes L Bonet-Ponce, A Beilina, CD Williamson, E Lindberg, JH Kluss, ... Science advances 6 (46), eabb2454, 2020 | 151 | 2020 |
| Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory-and oxidative stress-related pathways upon treatment with α-synuclein fibrils I Russo, A Kaganovich, J Ding, N Landeck, A Mamais, T Varanita, A Biosa, ... Neurobiology of disease 129, 67-78, 2019 | 64 | 2019 |
| Rapid, reproducible transduction of select forebrain regions by targeted recombinant virus injection into the neonatal mouse brain N Pilpel, N Landeck, M Klugmann, PH Seeburg, MK Schwarz Journal of neuroscience methods 182 (1), 55-63, 2009 | 63 | 2009 |
| Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis JO Johnson, R Chia, DE Miller, R Li, R Kumaran, Y Abramzon, ... JAMA neurology, 2021 | 55 | 2021 |
| Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia A Mamais, JH Kluss, L Bonet-Ponce, N Landeck, RG Langston, N Smith, ... PLoS biology 19 (12), e3001480, 2021 | 51 | 2021 |
| LAG3 is not expressed in human and murine neurons and does not modulate α‐synucleinopathies M Emmenegger, E De Cecco, M Hruska‐Plochan, T Eninger, ... EMBO Molecular Medicine 13 (9), e14745, 2021 | 49 | 2021 |
| A novel multiplex assay for simultaneous quantification of total and S129 phosphorylated human alpha-synuclein N Landeck, H Hall, MT Ardah, NK Majbour, OMA El-Agnaf, G Halliday, ... Molecular neurodegeneration 11 (1), 1-23, 2016 | 40 | 2016 |
| Extracellular clusterin limits the uptake of α‐synuclein fibrils by murine and human astrocytes A Filippini, V Mutti, G Faustini, F Longhena, I Ramazzina, F Rizzi, ... Glia 69 (3), 681-696, 2021 | 35 | 2021 |
| Characterization of cognitive deficits in rats overexpressing human alpha-synuclein in the ventral tegmental area and medial septum using recombinant adeno-associated viral vectors H Hall, M Jewett, N Landeck, N Nilsson, U Schagerlöf, G Leanza, D Kirik PLoS One 8 (5), e64844, 2013 | 32 | 2013 |
| Sequential screening nominates the Parkinson's disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosis GR Heaton, N Landeck, A Mamais, MA Nalls, J Nixon-Abell, R Kumaran, ... Neurobiology of disease 141, 104948, 2020 | 29 | 2020 |
| Toxic effects of human and rodent variants of alpha‐synuclein in vivo N Landeck, K Buck, D Kirik European Journal of Neuroscience 45 (4), 536-547, 2017 | 29 | 2017 |
| Ser129 phosphorylation of endogenous α-synuclein induced by overexpression of polo-like kinases 2 and 3 in nigral dopamine neurons is not detrimental to their survival and function K Buck, N Landeck, A Ulusoy, NK Majbour, OMA El-Agnaf, D Kirik Neurobiology of disease 78, 100-114, 2015 | 27 | 2015 |
| In vivo quantification of glial activation in minipigs overexpressing human α‐synuclein TP Lillethorup, AN Glud, N Landeck, AKO Alstrup, S Jakobsen, K Vang, ... Synapse 72 (12), e22060, 2018 | 16 | 2018 |
| Mutations in Auxilin cause parkinsonism via impaired clathrin-mediated trafficking at the Golgi apparatus and synapse DA Roosen, N Landeck, M Conti, N Smith, S Saez-Atienzar, J Ding, ... Biorxiv, 830802, 2019 | 13 | 2019 |
| Longitudinal monoaminergic PET imaging of chronic proteasome inhibition in minipigs TP Lillethorup, AN Glud, AKO Alstrup, O Noer, EHT Nielsen, AC Schacht, ... Scientific Reports 8 (1), 15715, 2018 | 13 | 2018 |
| Two C-terminal sequence variations determine differential neurotoxicity between human and mouse α-synuclein N Landeck, KE Strathearn, D Ysselstein, K Buck, S Dutta, S Banerjee, ... Molecular Neurodegeneration 15 (1), 1-23, 2020 | 8 | 2020 |
| Specific Detection of Physiological S129 Phosphorylated α-Synuclein in Tissue Using Proximity Ligation Assay R Arlinghaus, M Iba, E Masliah, MR Cookson, N Landeck Journal of Parkinson's Disease, 1-16, 2023 | 5 | 2023 |
| Pathogenic mutations in LRRK2 sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia A Mamais, N Landeck, RG Langston, L Bonet-Ponce, N Smith, A Beilina, ... | 5 | 2020 |
