| The central role of initiator caspase-9 in apoptosis signal transduction and the regulation of its activation and activity on the apoptosome ML Würstle, MA Laussmann, M Rehm Experimental cell research 318 (11), 1213-1220, 2012 | 313 | 2012 |
| Epigenome-wide association study identifies cardiac gene patterning and a novel class of biomarkers for heart failure B Meder, J Haas, F Sedaghat-Hamedani, E Kayvanpour, K Frese, A Lai, ... Circulation 136 (16), 1528-1544, 2017 | 166 | 2017 |
| Proteasome inhibition can induce an autophagy-dependent apical activation of caspase-8 MA Laussmann, E Passante, H Düssmann, JA Rauen, ML Würstle, ... Cell Death & Differentiation 18 (10), 1584-1597, 2011 | 153 | 2011 |
| Single-cell quantification of Bax activation and mathematical modelling suggest pore formation on minimal mitochondrial Bax accumulation H Düssmann, M Rehm, CG Concannon, S Anguissola, M Würstle, ... Cell Death & Differentiation 17 (2), 278-290, 2010 | 113 | 2010 |
| Web-based NGS data analysis using miRMaster: a large-scale meta-analysis of human miRNAs T Fehlmann, C Backes, M Kahraman, J Haas, N Ludwig, AE Posch, ... Nucleic acids research 45 (15), 8731-8744, 2017 | 71 | 2017 |
| Validating Alzheimer's disease micro RNAs using next-generation sequencing A Keller, C Backes, J Haas, P Leidinger, W Maetzler, C Deuschle, D Berg, ... Alzheimer's & Dementia 12 (5), 565-576, 2016 | 62 | 2016 |
| Orchestrating osteogenic differentiation of mesenchymal stem cells—Identification of placental growth factor as a mechanosensitive gene with a pro-osteogenic role RJ McCoy, A Widaa, KM Watters, M Wuerstle, RL Stallings, GP Duffy, ... Stem cells 31 (11), 2420-2431, 2013 | 54 | 2013 |
| Genomic structural variations lead to dysregulation of important coding and non‐coding RNA species in dilated cardiomyopathy J Haas, S Mester, A Lai, KS Frese, F Sedaghat‐Hamedani, E Kayvanpour, ... EMBO molecular medicine 10 (1), 107-120, 2018 | 45 | 2018 |
| Systems analysis of apoptosis protein expression allows the case-specific prediction of cell death responsiveness of melanoma cells ML Würstle, E Passante, CT Hellwig, M Leverkus, M Rehm Cell Death & Differentiation 20 (11), 1521-1531, 2013 | 44 | 2013 |
| A systems biology analysis of apoptosome formation and apoptosis execution supports allosteric procaspase-9 activation ML Würstle, M Rehm Journal of Biological Chemistry 289 (38), 26277-26289, 2014 | 39 | 2014 |
| The caspase-8 dimerization/dissociation balance is a highly potent regulator of caspase-8,-3,-6 signaling ML Würstle, MA Laussmann, M Rehm Journal of Biological Chemistry 285 (43), 33209-33218, 2010 | 39 | 2010 |
| From computational modelling of the intrinsic apoptosis pathway to a systems-based analysis of chemotherapy resistance: achievements, perspectives and challenges in systems … ML Würstle, E Zink, JHM Prehn, M Rehm Cell death & disease 5 (5), e1258-e1258, 2014 | 30 | 2014 |
| A stepwise integrated approach to personalized risk predictions in stage III colorectal cancer M Salvucci, ML Würstle, C Morgan, S Curry, M Cremona, AU Lindner, ... Clinical Cancer Research 23 (5), 1200-1212, 2017 | 25 | 2017 |
| Influence of next-generation sequencing and storage conditions on miRNA patterns generated from PAXgene blood C Backes, P Leidinger, G Altmann, M Wuerstle, B Meder, V Galata, ... Analytical chemistry 87 (17), 8910-8916, 2015 | 22 | 2015 |
| Predicting the cell death responsiveness and sensitization of glioma cells to TRAIL and temozolomide BC Weyhenmeyer, J Noonan, ML Würstle, FA Lincoln, G Johnston, ... Oncotarget 7 (38), 61295, 2016 | 20 | 2016 |
| An analysis of the truncated Bid-and ROS-dependent spatial propagation of mitochondrial permeabilization waves during apoptosis SF Jacob, ML Würstle, ME Delgado, M Rehm Journal of Biological Chemistry 291 (9), 4603-4613, 2016 | 10 | 2016 |
| Microscopy control system and method H Huber, H Dussmann, P Perrine, J Wenus, D Kalamatianos, M Wuerstle US Patent App. 12/725,013, 2010 | 10 | 2010 |
| Personalized computer simulation of diastolic function in heart failure A Amr, E Kayvanpour, F Sedaghat-Hamedani, T Passerini, V Mihalef, ... Genomics, Proteomics and Bioinformatics 14 (4), 244-252, 2016 | 7 | 2016 |
| A machine learning platform to optimize the translation of personalized network models to the clinic M Salvucci, A Rahman, AJ Resler, GM Udupi, DA McNamara, EW Kay, ... JCO clinical cancer informatics 3, 1-17, 2019 | 6 | 2019 |
| Healthcare network O Frings, T Boettger, U Hartung, R Kartmann, R Dorothee, B Krueger, ... US Patent App. 17/024,796, 2021 | 3 | 2021 |
Prof Dr Markus Morrison (Rehm)Director, Institute of Cell Biology and Immunology, University of Stuttgart, GermanyCorreu electrònic verificat a izi.uni-stuttgart.de
