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Jan K. Hennigs
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In pulmonary arterial hypertension, reduced BMPR2 promotes endothelial-to-mesenchymal transition via HMGA1 and its target slug
RK Hopper, JRAJ Moonen, I Diebold, A Cao, CJ Rhodes, NF Tojais, ...
Circulation 133 (18), 1783-1794, 2016
2142016
BMPR2 Preserves Mitochondrial Function and DNA during Reoxygenation to Promote Endothelial Cell Survival and Reverse Pulmonary Hypertension
I Diebold, JK Hennigs, K Miyagawa, CG Li, NP Nickel, M Kaschwich, ...
Cell Metabolism 21 (4), 596-608, 2015
2022015
Elafin reverses pulmonary hypertension via caveolin-1–dependent bone morphogenetic protein signaling
NP Nickel, E Spiekerkoetter, M Gu, CG Li, H Li, M Kaschwich, I Diebold, ...
American journal of respiratory and critical care medicine 191 (11), 1273-1286, 2015
1402015
Vascular Endothelial Cells: Heterogeneity and Targeting Approaches
JK Hennigs, C Matuszcak, M Trepel, J Körbelin
Cells 10 (10), 2712, 2021
1012021
Transcription Factor Runx2 Promotes Aortic Fibrosis and Stiffness in Type 2 Diabetes Mellitus
U Raaz, IN Schellinger, E Chernogubova, C Warnecke, Y Kayama, ...
Circulation research 117 (6), 513-524, 2015
942015
Multi tyrosine kinase inhibitor dasatinib as novel cause of severe pre-capillary pulmonary hypertension?
JK Hennigs, G Keller, HJ Baumann, F Honecker, S Kluge, C Bokemeyer, ...
BMC pulmonary medicine 11 (1), 30, 2011
942011
Smooth Muscle Contact Drives Endothelial Regeneration by BMPR2-Notch1–Mediated Metabolic and Epigenetic Changes
K Miyagawa, M Shi, PI Chen, JK Hennigs, Z Zhao, M Wang, CG Li, T Saito, ...
Circulation research 124 (2), 211-224, 2019
912019
RNA Sequencing Analysis Detection of a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension
CJ Rhodes, H Im, A Cao, JK Hennigs, L Wang, S Sa, PI Chen, NP Nickel, ...
American journal of respiratory and critical care medicine 192 (3), 356-366, 2015
892015
Amphetamines promote mitochondrial dysfunction and DNA damage in pulmonary hypertension
PI Chen, A Cao, K Miyagawa, NF Tojais, JK Hennigs, CG Li, NM Sweeney, ...
JCI insight 2 (2), 2017
832017
Fiber optic bronchoscopy in patients with acute hypoxemic respiratory failure requiring noninvasive ventilation-a feasibility study
HJ Baumann, H Klose, M Simon, T Ghadban, SA Braune, JK Hennigs, ...
Critical Care 15 (4), R179, 2011
712011
PPARγ Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis
CG Li, C Mahon, NM Sweeney, E Verschueren, V Kantamani, D Li, ...
Cell reports 26 (5), 1333-1343. e7, 2019
662019
Myeloperoxidase aggravates pulmonary arterial hypertension by activation of vascular Rho-kinase
A Klinke, E Berghausen, K Friedrichs, S Molz, D Lau, L Remane, M Berlin, ...
JCI insight 3 (11), 2018
582018
Upregulation of human endogenous retrovirus-K is linked to immunity and inflammation in pulmonary arterial hypertension
T Saito, K Miyagawa, SY Chen, R Tamosiuniene, L Wang, O Sharpe, ...
Circulation 136 (20), 1920-1935, 2017
542017
Low intensity, long-term outpatient rehabilitation in COPD: a randomised controlled trial
HJ Baumann, S Kluge, K Rummel, H Klose, JK Hennigs, T Schmoller, ...
Respiratory research 13 (1), 86, 2012
542012
Enhanced Caspase Activity Contributes to Aortic Wall Remodeling and Early Aneurysm Development in a Murine Model of Marfan Syndrome
FC Emrich, H Okamura, AR Dalal, K Penov, DR Merk, U Raaz, ...
Arteriosclerosis, thrombosis, and vascular biology 35 (1), 146-154, 2015
522015
The Endothelial ADMA/NO Pathway in Hypoxia-Related Chronic Respiratory Diseases
N Lüneburg, L Harbaum, J Hennigs
BioMed research international 2014, 2014
462014
Increased Pyruvate Dehydrogenase Kinase 4 Expression in Lung Pericytes Is Associated with Reduced Endothelial-Pericyte Interactions and Small Vessel Loss in Pulmonary Arterial …
K Yuan, NY Shao, JK Hennigs, M Discipulo, ME Orcholski, E Shamskhou, ...
The American Journal of Pathology 186 (9), 2500-2514, 2016
432016
PPARγ-p53-Mediated Vasculoregenerative Program to Reverse Pulmonary Hypertension
JK Hennigs, A Cao, CG Li, M Shi, J Mienert, K Miyagawa, J Körbelin, ...
Circulation Research 128 (3), 401-418, 2021
422021
Pathobiology, pathology and genetics of pulmonary hypertension: Update from the Cologne Consensus Conference 2018
A Olschewski, EM Berghausen, CA Eichstaedt, BK Fleischmann, E Grünig, ...
International journal of cardiology 272, 4-10, 2018
382018
Role of Toll-like receptors and interferon regulatory factors in different experimental heart failure models of diverse etiology: IRF7 as novel cardiovascular stress-inducible …
PM Becher, S Hinrichs, N Fluschnik, JK Hennigs, K Klingel, ...
PloS one 13 (3), e0193844, 2018
332018
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