The helicase aquarius/EMB-4 is required to overcome intronic barriers to allow nuclear RNAi pathways to heritably silence transcription A Akay, T Di Domenico, KM Suen, A Nabih, GE Parada, M Larance, ... Developmental cell 42 (3), 241-255. e6, 2017 | 68 | 2017 |
Targeting tumor phenotypic plasticity and metabolic remodeling in adaptive cross-drug tolerance A Goldman, S Khiste, E Freinkman, A Dhawan, B Majumder, J Mondal, ... Science signaling 12 (595), eaas8779, 2019 | 57 | 2019 |
Alternative splicing modulation by G-quadruplexes I Georgakopoulos-Soares, GE Parada, HY Wong, R Medhi, G Furlan, ... Nature communications 13 (1), 2404, 2022 | 51 | 2022 |
RNA uridyl transferases TUT4/7 differentially regulate miRNA variants depending on the cancer cell type R Medhi, J Price, G Furlan, B Gorges, A Sapetschnig, EA Miska Rna 28 (3), 353-370, 2022 | 13 | 2022 |
The Aquarius/EMB-4 helicase licenses co-transcriptional gene silencing A Akay, TD Domenico, KM Suen, A Nabih, GE Parada, M Larance, ... bioRxiv, 089763, 2016 | 3 | 2016 |
A novel autotaxin inhibitor, IOA-289, modulates tumor, immune and stromal cell function and has monotherapy activity in fibrotic cancer models MA Deken, K Niewola-Staszkowska, E Matas-Rico, A Fraser, R Medhi, ... Journal for ImmunoTherapy of Cancer 9, A967-A967, 2021 | 2 | 2021 |
Regulation of microRNA expression by the adaptor protein GRB2 AK Stainthorp, CC Lin, D Wang, R Medhi, Z Ahmed, KM Suen, EA Miska, ... Scientific reports 13 (1), 9784, 2023 | 1 | 2023 |
Targeting autotaxin to suppress stromal signaling in the tumor microenvironment to improve outcome to therapy in fibrotic tumor types Z Johnson, M Deken, R Medhi, L Maggs, A Carruthers, A Cheasty, ... Proceedings of the American Association for Cancer Research Annual Meeting …, 2022 | 1 | 2022 |
131P Translating a novel autotaxin inhibitor from preclinical proof of concept in pancreatic cancer to a biomarker response in human subjects S Milleri, M Deken, R Medhi, A Carruthers, A Tagliavini, A Nizzardo, ... Annals of Oncology 32, S1434, 2021 | 1 | 2021 |
Nanomaterials and Cardiovascular Toxicity A Paul, HA Kindi, R Medhi, V Manoharan, S Prakash, D Shum-Tim Heart and Toxins, 547–570, 2015 | 1 | 2015 |
Terminal uridyl transferases: TUT4/7-mediated RNA metabolism in cancer R Medhi | | 2021 |
Abstract A58: Temporal dynamics underpin metabolism-driven cancer therapy cross-resistance A Goldman, A Dhawan, R Medhi, M Kohandel, S Sengupta Molecular Cancer Research 14 (1_Supplement), A58-A58, 2016 | | 2016 |