Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling P Sanchez, AM Hernández, B Stecca, AJ Kahler, AM DeGueme, A Barrett, ... Proceedings of the National Academy of Sciences 101 (34), 12561-12566, 2004 | 676 | 2004 |
Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways B Stecca, C Mas, V Clement, M Zbinden, R Correa, V Piguet, F Beermann, ... Proceedings of the National Academy of Sciences 104 (14), 5895-5900, 2007 | 657 | 2007 |
The Gli code: an information nexus regulating cell fate, stemness and cancer AR i Altaba, C Mas, B Stecca Trends in cell biology 17 (9), 438-447, 2007 | 411 | 2007 |
Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals B Stecca, A Ruiz i Altaba Journal of molecular cell biology 2 (2), 84-95, 2010 | 324 | 2010 |
Non-canonical hedgehog signaling pathway in cancer: activation of GLI transcription factors beyond smoothened S Pietrobono, S Gagliardi, B Stecca Frontiers in genetics 10, 556, 2019 | 314 | 2019 |
A GLI1‐p53 inhibitory loop controls neural stem cell and tumour cell numbers B Stecca, A Ruiz i Altaba The EMBO journal 28 (6), 663-676, 2009 | 290 | 2009 |
SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells R Santini, S Pietrobono, S Pandolfi, V Montagnani, M D'Amico, ... Oncogene 33 (38), 4697-4708, 2014 | 242 | 2014 |
Hedgehog-GLI signaling drives self-renewal and tumorigenicity of human melanoma-initiating cells R Santini, MC Vinci, S Pandolfi, JY Penachioni, V Montagnani, B Olivito, ... Stem cells 30 (9), 1808-1818, 2012 | 184 | 2012 |
Hedgehog–Gli signaling in brain tumors: stem cells and paradevelopmental programs in cancer AR i Altaba, B Stecca, P Sánchez Cancer letters 204 (2), 145-157, 2004 | 125 | 2004 |
The evolution of lipophilin genes from invertebrates to tetrapods: DM-20 cannot replace proteolipid protein in CNS myelin B Stecca, CM Southwood, A Gragerov, KA Kelley, VL Friedrich, A Gow Journal of Neuroscience 20 (11), 4002-4010, 2000 | 113 | 2000 |
KLF4 is regulated by RAS/RAF/MEK/ERK signaling through E2F1 and promotes melanoma cell growth M Riverso, V Montagnani, B Stecca Oncogene 36 (23), 3322-3333, 2017 | 111 | 2017 |
Impact of ERK5 on the Hallmarks of Cancer B Stecca, E Rovida International journal of molecular sciences 20 (6), 1426, 2019 | 103 | 2019 |
Aberrant dipeptidyl peptidase IV (DPP IV/CD26) expression in human hepatocellular carcinoma BA Stecca, B Nardo, P Chieco, A Mazziotti, L Bolondi, A Cavallari Journal of hepatology 27 (2), 337-345, 1997 | 103 | 1997 |
Cooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapy S Pandolfi, B Stecca Expert reviews in molecular medicine 17, e5, 2015 | 100 | 2015 |
Brain as a paradigm of organ growth: Hedgehog–Gli signaling in neural stem cells and brain tumors B Stecca, A Ruiz i Altaba Journal of neurobiology 64 (4), 476-490, 2005 | 100 | 2005 |
Aberrant sialylation in cancer: biomarker and potential target for therapeutic intervention? S Pietrobono, B Stecca Cancers 13 (9), 2014, 2021 | 92 | 2021 |
Mitogen-activated protein kinases and Hedgehog-GLI signaling in cancer: A crosstalk providing therapeutic opportunities? E Rovida, B Stecca Seminars in cancer biology 35, 154-167, 2015 | 83 | 2015 |
Cooperative requirement of the Gli proteins in neurogenesis V Nguyen, AL Chokas, B Stecca, AR Altaba Oxford University Press for The Company of Biologists Limited 132 (14), 3267 …, 2005 | 81 | 2005 |
The acidic tumor microenvironment drives a stem-like phenotype in melanoma cells E Andreucci, S Peppicelli, J Ruzzolini, F Bianchini, A Biagioni, L Papucci, ... Journal of Molecular Medicine 98, 1431-1446, 2020 | 76 | 2020 |
ERK5 is activated by oncogenic BRAF and promotes melanoma growth I Tusa, S Gagliardi, A Tubita, S Pandolfi, C Urso, L Borgognoni, J Wang, ... Oncogene 37 (19), 2601-2614, 2018 | 74 | 2018 |