Robert Fagan

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Neil FairweatherImperial College LondonVerified email at imperial.ac.uk
Smith SGTrinity College DublinVerified email at tcd.ie
Trevor D LawleyWellcome Trust Sanger InstituteVerified email at sanger.ac.uk
Lars BarquistUniversity of Toronto; Helmholtz Institute for RNA-based Infection ResearchVerified email at helmholtz-hiri.de
Gordon DouganUniversity of CambridgeVerified email at cam.ac.uk
Vivienne MahonVerified email at tcd.ie
Per A BulloughSheffieldVerified email at sheffield.ac.uk
Helen Alexandra ShawResearch fellow, National Institute for Biological Standards and ControlsVerified email at nibsc.org
Oishik BanerjiPostdoctoral researcher, Institute of Structural and Molecular Biology (ISMB), Birkbeck, UniversityVerified email at mail.cryst.bbk.ac.uk
Brendan WrenProfessor of Pathogen Molecular BiologyVerified email at lshtm.ac.uk
Roy ChaudhuriLecturer in Bioinformatics, University of SheffieldVerified email at sheffield.ac.uk
Edward W. TateImperial College London & Francis Crick InstituteVerified email at imperial.ac.uk
Emeritus Professor Anne MoirDepartment of Molecular Biology & Biotechnology, The University of SheffieldVerified email at sheffield.ac.uk
sandra c stringerVerified email at ifr.ac.uk
Nic MullinUniversity of SheffieldVerified email at sheffield.ac.uk
Amy K. CainARC Future Research Fellow and Associate Professor, Macquarie University, Sydney, AustraliaVerified email at mq.edu.au
Christine J. BoinettWellcome Sanger InstituteVerified email at sanger.ac.uk
David Albesa-JovéInstituto Biofisika (UPV/EHU, CSIC)Verified email at ehu.eus
Stephane MesnageSenior lecturer, MBB department, University of SheffieldVerified email at sheffield.ac.uk
Wiep Klaas SmitsAssociate Professor/Principal Investigator, Leiden University Medical CenterVerified email at lumc.nl

Robert Fagan

Senior Lecturer, School of Biosciences, University of Sheffield

Verified email at sheffield.ac.uk - Homepage

Microbiology


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A molecular Swiss army knife: OmpA structure, function and expression SGJ Smith, V Mahon, MA Lambert, RP Fagan FEMS microbiology letters 273 (1), 1-11, 2007	486	2007
The Clostridium difficile spo0A Gene Is a Persistence and Transmission Factor LJ Deakin, S Clare, RP Fagan, LF Dawson, DJ Pickard, MR West, ... Infection and immunity 80 (8), 2704-2711, 2012	386	2012
Biogenesis and functions of bacterial S-layers RP Fagan, NF Fairweather Nature Reviews Microbiology 12 (3), 211-222, 2014	363	2014
Clostridium difficile has two parallel and essential Sec secretion systems RP Fagan, NF Fairweather Journal of Biological Chemistry 286 (31), 27483-27493, 2011	257	2011
High-Throughput Analysis of Gene Essentiality and Sporulation in Clostridium difficile M Dembek, L Barquist, CJ Boinett, AK Cain, M Mayho, TD Lawley, ... mBio 6 (2), e02383-14, 2015	171	2015
Structural insights into the molecular organization of the S‐layer from Clostridium difficile RP Fagan, D Albesa‐Jové, O Qazi, DI Svergun, KA Brown, ... Molecular microbiology 71 (5), 1308-1322, 2009	169	2009
Functional genomics reveals that Clostridium difficileSpo0A coordinates sporulation, virulence and metabolism LJ Pettit, HP Browne, L Yu, WK Smits, RP Fagan, L Barquist, MJ Martin, ... BMC genomics 15, 1-15, 2014	158	2014
The Clostridium difficile cell wall protein CwpV is antigenically variable between strains, but exhibits conserved aggregation-promoting function CB Reynolds, JE Emerson, L de la Riva, RP Fagan, NF Fairweather PLoS Pathog 7 (4), e1002024-e1002024, 2011	132	2011
A novel genetic switch controls phase variable expression of CwpV, a Clostridium difficile cell wall protein JE Emerson, CB Reynolds, RP Fagan, HA Shaw, D Goulding, ... Molecular microbiology 74 (3), 541-556, 2009	128	2009
A proposed nomenclature for cell wall proteins of Clostridium difficile RP Fagan, C Janoir, A Collignon, P Mastrantonio, IR Poxton, ... Journal of medical microbiology 60 (8), 1225-1228, 2011	76	2011
Chemical probes of surface layer biogenesis in Clostridium difficile THT Dang, L Riva, RP Fagan, EM Storck, WP Heal, C Janoir, ... ACS Chemical Biology 5 (3), 279-285, 2010	76	2010
New class of precision antimicrobials redefines role of Clostridium difficile S-layer in virulence and viability JA Kirk, D Gebhart, AM Buckley, S Lok, D Scholl, GR Douce, GR Govoni, ... Science Translational Medicine 9 (406), eaah6813, 2017	75	2017
Lighting Up Clostridium Difficile: Reporting Gene Expression Using Fluorescent Lov Domains AM Buckley, C Jukes, D Candlish, JJ Irvine, J Spencer, RP Fagan, AJ Roe, ... Scientific Reports 6, 23463, 2016	74	2016
Clostridium difficile surface proteins are anchored to the cell wall using CWB2 motifs that recognise the anionic polymer PSII SE Willing, T Candela, HA Shaw, Z Seager, S Mesnage, RP Fagan, ... Molecular microbiology 96 (3), 596-608, 2015	70	2015
Characteristics of the Clostridium difficile cell envelope and its importance in therapeutics JA Kirk, O Banerji, RP Fagan Microbial Biotechnology 10 (1), 76-90, 2017	68	2017
Heat shock increases conjugation efficiency in Clostridium difficile JA Kirk, RP Fagan Anaerobe 42, 1-5, 2016	66	2016
The hek outer membrane protein of Escherichia coli strain RS218 binds to proteoglycan and utilizes a single extracellular loop for adherence, invasion, and autoaggregation RP Fagan, MA Lambert, SGJ Smith Infection and immunity 76 (3), 1135-1142, 2008	52	2008
The Hek outer membrane protein of Escherichia coli is an auto‐aggregating adhesin and invasin RP Fagan, SGJ Smith FEMS microbiology letters 269 (2), 248-255, 2007	52	2007
An RNA-centric global view of Clostridioides difficile reveals broad activity of Hfq in a clinically important gram-positive bacterium M Fuchs, V Lamm-Schmidt, J Sulzer, F Ponath, L Jenniches, JA Kirk, ... Proceedings of the National Academy of Sciences 118 (25), e2103579118, 2021	36	2021
Pathogenicity and virulence of Clostridioides difficile JE Buddle, RP Fagan Virulence 14 (1), 2150452, 2023	30	2023

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