Smarcal1-mediated fork reversal triggers Mre11-dependent degradation of nascent DNA in the absence of Brca2 and stable Rad51 nucleofilaments AM Kolinjivadi, V Sannino, A De Antoni, K Zadorozhny, M Kilkenny, ... Molecular cell 67 (5), 867-881. e7, 2017 | 340 | 2017 |
A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome AC Simon, JC Zhou, RL Perera, F van Deursen, C Evrin, ME Ivanova, ... Nature 510 (7504), 293-297, 2014 | 225 | 2014 |
Crystal structure of the rad9-rad1-hus1 DNA damage checkpoint complex—implications for clamp loading and regulation AS Doré, ML Kilkenny, NJ Rzechorzek, LH Pearl Molecular cell 34 (6), 735-745, 2009 | 150 | 2009 |
Ctf4 is a hub in the eukaryotic replisome that links multiple CIP-box proteins to the CMG helicase F Villa, AC Simon, MAO Bazan, ML Kilkenny, D Wirthensohn, M Wightman, ... Molecular cell 63 (3), 385-396, 2016 | 127 | 2016 |
Mechanism for priming DNA synthesis by yeast DNA polymerase α RL Perera, R Torella, S Klinge, ML Kilkenny, JD Maman, L Pellegrini Elife 2, e00482, 2013 | 117 | 2013 |
Structure of an archaeal PCNA1–PCNA2–FEN1 complex: elucidating PCNA subunit and client enzyme specificity AS Dore, ML Kilkenny, SA Jones, AW Oliver, SM Roe, SD Bell, LH Pearl Nucleic Acids Research 34 (16), 4515-4526, 2006 | 87 | 2006 |
Structural and functional analysis of the Crb2–BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repair ML Kilkenny, AS Doré, SM Roe, K Nestoras, JCY Ho, FZ Watts, LH Pearl Genes & development 22 (15), 2034-2047, 2008 | 82 | 2008 |
Structural constraints on protein self‐processing in l‐aspartate‐α‐decarboxylase F Schmitzberger, ML Kilkenny, CMC Lobley, ME Webb, M Vinkovic, ... The EMBO journal, 2003 | 81 | 2003 |
Flexible tethering of primase and DNA Pol α in the eukaryotic primosome R Núñez-Ramírez, S Klinge, L Sauguet, R Melero, MA Recuero-Checa, ... Nucleic acids research 39 (18), 8187-8199, 2011 | 77 | 2011 |
Structures of human primase reveal design of nucleotide elongation site and mode of Pol α tethering ML Kilkenny, MA Longo, RL Perera, L Pellegrini Proceedings of the National Academy of Sciences 110 (40), 15961-15966, 2013 | 74 | 2013 |
Timeless couples G‐quadruplex detection with processing by DDX 11 helicase during DNA replication LK Lerner, S Holzer, ML Kilkenny, S Šviković, P Murat, D Schiavone, ... The EMBO journal 39 (18), e104185, 2020 | 60 | 2020 |
The proteasome controls ESCRT-III–mediated cell division in an archaeon G Tarrason Risa, F Hurtig, S Bray, AE Hafner, L Harker-Kirschneck, ... Science 369 (6504), eaaz2532, 2020 | 56 | 2020 |
The human CTF4-orthologue AND-1 interacts with DNA polymerase α/primase via its unique C-terminal HMG box ML Kilkenny, AC Simon, J Mainwaring, D Wirthensohn, S Holzer, ... Open Biology 7 (11), 170217, 2017 | 50 | 2017 |
A conserved motif in the C-terminal tail of DNA polymerase α tethers primase to the eukaryotic replisome ML Kilkenny, G De Piccoli, RL Perera, K Labib, L Pellegrini Journal of Biological Chemistry 287 (28), 23740-23747, 2012 | 47 | 2012 |
Involvement of a eukaryotic-like ubiquitin-related modifier in the proteasome pathway of the archaeon Sulfolobus acidocaldarius RS Anjum, SM Bray, JK Blackwood, ML Kilkenny, MA Coelho, BM Foster, ... Nature communications 6 (1), 8163, 2015 | 36 | 2015 |
One-and two-dimensional coordination polymers of zinc (II) with pyrazine. Solid state reactions and decomposition kinetics of the interconversion reactions SA Bourne, M Kilkenny, LR Nassimbeni Journal of the Chemical Society, Dalton Transactions, 1176-1179, 2001 | 35 | 2001 |
Metallacycloalkanes–Synthesis, Structure and Reactivity of Medium to Large Ring Compounds B Blom, H Clayton, M Kilkenny, JR Moss Advances in Organometallic Chemistry 54, 149-205, 2006 | 31 | 2006 |
Primer synthesis by a eukaryotic-like archaeal primase is independent of its Fe-S cluster S Holzer, J Yan, ML Kilkenny, SD Bell, L Pellegrini Nature Communications 8 (1), 1718, 2017 | 27 | 2017 |
Structural basis for the interaction of SARS‐CoV‐2 virulence factor nsp1 with DNA polymerase α–primase ML Kilkenny, CE Veale, A Guppy, SW Hardwick, DY Chirgadze, ... Protein Science 31 (2), 333-344, 2022 | 25 | 2022 |
Structural basis for inhibition of human primase by arabinofuranosyl nucleoside analogues fludarabine and vidarabine S Holzer, NJ Rzechorzek, IR Short, M Jenkyn-Bedford, L Pellegrini, ... ACS Chemical Biology 14 (9), 1904-1912, 2019 | 24 | 2019 |