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Jaydeep Sinha
Jaydeep Sinha
University of North Carolina Eshelman School of Pharmacy
Dirección de correo verificada de unc.edu
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Design, synthesis, and pharmacokinetic evaluation of phosphate and amino acid ester prodrugs for improving the oral bioavailability of the HIV-1 protease inhibitor atazanavir
M AM Subbaiah, S Mandlekar, S Desikan, T Ramar, L Subramani, ...
Journal of Medicinal Chemistry 62 (7), 3553-3574, 2019
262019
Absorption and cleavage of enalapril, a carboxyl ester prodrug, in the rat intestine: in vitro, in situ intestinal perfusion and portal vein cannulation models
VK Holenarsipur, N Gaud, J Sinha, S Sivaprasad, P Bhutani, ...
Biopharmaceutics & drug disposition 36 (6), 385-397, 2015
242015
Characterizing pharmacokinetics in children with obesity—physiological, drug, patient, and methodological considerations
JG Gerhart, S Balevic, J Sinha, EM Perrin, J Wang, AN Edginton, ...
Frontiers in Pharmacology 13, 818726, 2022
222022
Choosing the allometric exponent in covariate model building
J Sinha, HS Al-Sallami, SB Duffull
Clinical Pharmacokinetics 58, 89-100, 2019
212019
A Review of the Methods and Associated Mathematical Models Used in the Measurement of Fat-Free Mass
J Sinha, SB Duffull, HS Al-Sallami
Clinical Pharmacokinetics, 2018
202018
Methyl cellulose based sustained release thermosensitive in situ fast gelling ocular delivery of ketorolac tromethamine
M Bhowmik, S Das, J Sinha, S Bag, D Chattopadhyay, LK Ghosh
Asian Journal of Chemistry 22 (3), 2147, 2010
172010
Pediatric drug‐drug interaction evaluation: drug, patient population, and methodological considerations
D Gonzalez, J Sinha
The Journal of Clinical Pharmacology 61, S175-S187, 2021
162021
Development and evaluation of a virtual population of children with obesity for physiologically based pharmacokinetic modeling
JG Gerhart, FO Carreño, AN Edginton, J Sinha, EM Perrin, KR Kumar, ...
Clinical pharmacokinetics, 1-14, 2022
152022
Evaluating the relationship between lean liver volume and fat-free mass
J Sinha, SB Duffull, B Green, HS Al-Sallami
Clinical Pharmacokinetics 59, 475-483, 2020
122020
Use of real‐world data and physiologically‐based pharmacokinetic modeling to characterize enoxaparin disposition in children with obesity
JG Gerhart, FO Carreño, MS Loop, CR Lee, AN Edginton, J Sinha, ...
Clinical Pharmacology & Therapeutics 112 (2), 391-403, 2022
112022
Physiologically‐based pharmacokinetic modeling of oxcarbazepine and levetiracetam during adjunctive antiepileptic therapy in children and adolescents
J Sinha, E Karatza, D Gonzalez
CPT: Pharmacometrics & Systems Pharmacology 11 (2), 225-239, 2022
92022
An extension of Janmahasatian’s fat-free mass model for universal application across populations of different ethnicities
J Sinha, HS Al-Sallami, SB Duffull
Clinical Pharmacokinetics 59 (9), 1161-1170, 2020
72020
Evaluating lean liver volume as a potential scaler for in vitro-in vivo extrapolation of drug clearance in obesity using the model drug antipyrine
J Sinha, SB Duffull, B Green, HS Al-Sallami
Current Drug Metabolism 21 (10), 746-750, 2020
22020
Population Pharmacokinetics of Posaconazole in Immune-Compromised Children and Assessment of Target Attainment in Invasive Fungal Disease
S McCann, J Sinha, WS Wilson, CJ McKinzie, LM Garner, D Gonzalez
Clinical Pharmacokinetics 62 (7), 997-1009, 2023
12023
USE OF POPULATION MODELING TO CHARACTERIZE THE PHARMACOKINETICS OF OXCARBAZEPINE AND ITS METABOLITE IN CHILDREN AND ADOLESCENTS WITH OBESITY.
J Sinha, K Zimmerman, S Balevic, W Muller, C Hornik, M Rathore, ...
CLINICAL PHARMACOLOGY & THERAPEUTICS 111, S48-S48, 2022
12022
Advanced approaches in pediatric clinical pharmacology
H Al-Sallami, A Diniz, J Sinha, E Karatza, K Allegaert
Frontiers in Pharmacology 15, 1372290, 2024
2024
Thanks to our Reviewers of 2022!
L Aarons, F Agbo, K Allegaert, TM Atanackovic, R Baillie, P Bloomingdale, ...
Journal of Pharmacokinetics and Pharmacodynamics 50, 75, 2023
2023
Corrigendum: Abstracts of papers, 2022 Annual Meeting
J Sinha, K Zimmerman, S Balevic, W Muller, C Hornik, M Rathore, ...
Clinical Pharmacology & Therapeutics 112 (2), 412, 2022
2022
# 3 Assessment of drug-drug interaction in pediatric drug development: Application of physiology-based pharmacokinetic modeling
J Sinha
Journal of Pharmaceutical Chemistry 8 (Supplement), 2022
2022
Abstracts of papers, 2022 Annual Meeting (vol 111, pg S5, 2022)
J Sinha, K Zimmerman, S Balevic, W Muller, C Hornik, M Rathore, ...
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2022
2022
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