Design, synthesis, and pharmacokinetic evaluation of phosphate and amino acid ester prodrugs for improving the oral bioavailability of the HIV-1 protease inhibitor atazanavir M AM Subbaiah, S Mandlekar, S Desikan, T Ramar, L Subramani, ... Journal of Medicinal Chemistry 62 (7), 3553-3574, 2019 | 26 | 2019 |
Absorption and cleavage of enalapril, a carboxyl ester prodrug, in the rat intestine: in vitro, in situ intestinal perfusion and portal vein cannulation models VK Holenarsipur, N Gaud, J Sinha, S Sivaprasad, P Bhutani, ... Biopharmaceutics & drug disposition 36 (6), 385-397, 2015 | 24 | 2015 |
Characterizing pharmacokinetics in children with obesity—physiological, drug, patient, and methodological considerations JG Gerhart, S Balevic, J Sinha, EM Perrin, J Wang, AN Edginton, ... Frontiers in Pharmacology 13, 818726, 2022 | 22 | 2022 |
Choosing the allometric exponent in covariate model building J Sinha, HS Al-Sallami, SB Duffull Clinical Pharmacokinetics 58, 89-100, 2019 | 21 | 2019 |
A Review of the Methods and Associated Mathematical Models Used in the Measurement of Fat-Free Mass J Sinha, SB Duffull, HS Al-Sallami Clinical Pharmacokinetics, 2018 | 20 | 2018 |
Methyl cellulose based sustained release thermosensitive in situ fast gelling ocular delivery of ketorolac tromethamine M Bhowmik, S Das, J Sinha, S Bag, D Chattopadhyay, LK Ghosh Asian Journal of Chemistry 22 (3), 2147, 2010 | 17 | 2010 |
Pediatric drug‐drug interaction evaluation: drug, patient population, and methodological considerations D Gonzalez, J Sinha The Journal of Clinical Pharmacology 61, S175-S187, 2021 | 16 | 2021 |
Development and evaluation of a virtual population of children with obesity for physiologically based pharmacokinetic modeling JG Gerhart, FO Carreño, AN Edginton, J Sinha, EM Perrin, KR Kumar, ... Clinical pharmacokinetics, 1-14, 2022 | 15 | 2022 |
Evaluating the relationship between lean liver volume and fat-free mass J Sinha, SB Duffull, B Green, HS Al-Sallami Clinical Pharmacokinetics 59, 475-483, 2020 | 12 | 2020 |
Use of real‐world data and physiologically‐based pharmacokinetic modeling to characterize enoxaparin disposition in children with obesity JG Gerhart, FO Carreño, MS Loop, CR Lee, AN Edginton, J Sinha, ... Clinical Pharmacology & Therapeutics 112 (2), 391-403, 2022 | 11 | 2022 |
Physiologically‐based pharmacokinetic modeling of oxcarbazepine and levetiracetam during adjunctive antiepileptic therapy in children and adolescents J Sinha, E Karatza, D Gonzalez CPT: Pharmacometrics & Systems Pharmacology 11 (2), 225-239, 2022 | 9 | 2022 |
An extension of Janmahasatian’s fat-free mass model for universal application across populations of different ethnicities J Sinha, HS Al-Sallami, SB Duffull Clinical Pharmacokinetics 59 (9), 1161-1170, 2020 | 7 | 2020 |
Evaluating lean liver volume as a potential scaler for in vitro-in vivo extrapolation of drug clearance in obesity using the model drug antipyrine J Sinha, SB Duffull, B Green, HS Al-Sallami Current Drug Metabolism 21 (10), 746-750, 2020 | 2 | 2020 |
Population Pharmacokinetics of Posaconazole in Immune-Compromised Children and Assessment of Target Attainment in Invasive Fungal Disease S McCann, J Sinha, WS Wilson, CJ McKinzie, LM Garner, D Gonzalez Clinical Pharmacokinetics 62 (7), 997-1009, 2023 | 1 | 2023 |
USE OF POPULATION MODELING TO CHARACTERIZE THE PHARMACOKINETICS OF OXCARBAZEPINE AND ITS METABOLITE IN CHILDREN AND ADOLESCENTS WITH OBESITY. J Sinha, K Zimmerman, S Balevic, W Muller, C Hornik, M Rathore, ... CLINICAL PHARMACOLOGY & THERAPEUTICS 111, S48-S48, 2022 | 1 | 2022 |
Advanced approaches in pediatric clinical pharmacology H Al-Sallami, A Diniz, J Sinha, E Karatza, K Allegaert Frontiers in Pharmacology 15, 1372290, 2024 | | 2024 |
Thanks to our Reviewers of 2022! L Aarons, F Agbo, K Allegaert, TM Atanackovic, R Baillie, P Bloomingdale, ... Journal of Pharmacokinetics and Pharmacodynamics 50, 75, 2023 | | 2023 |
Corrigendum: Abstracts of papers, 2022 Annual Meeting J Sinha, K Zimmerman, S Balevic, W Muller, C Hornik, M Rathore, ... Clinical Pharmacology & Therapeutics 112 (2), 412, 2022 | | 2022 |
# 3 Assessment of drug-drug interaction in pediatric drug development: Application of physiology-based pharmacokinetic modeling J Sinha Journal of Pharmaceutical Chemistry 8 (Supplement), 2022 | | 2022 |
Abstracts of papers, 2022 Annual Meeting (vol 111, pg S5, 2022) J Sinha, K Zimmerman, S Balevic, W Muller, C Hornik, M Rathore, ... CLINICAL PHARMACOLOGY & THERAPEUTICS, 2022 | | 2022 |