| Malignant astrocytic glioma: genetics, biology, and paths to treatment FB Furnari, T Fenton, RM Bachoo, A Mukasa, JM Stommel, A Stegh, ... Genes & development 21 (21), 2683-2710, 2007 | 2874 | 2007 |
| Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies JM Stommel, AC Kimmelman, H Ying, R Nabioullin, AH Ponugoti, ... Science 318 (5848), 287-290, 2007 | 1114 | 2007 |
| Spherical nucleic acid nanoparticle conjugates as an RNAi-based therapy for glioblastoma SA Jensen, ES Day, CH Ko, LA Hurley, JP Luciano, FM Kouri, TJ Merkel, ... Science translational medicine 5 (209), 209ra152-209ra152, 2013 | 586 | 2013 |
| SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression Z Ding, CJ Wu, GC Chu, Y Xiao, D Ho, J Zhang, SR Perry, ES Labrot, ... Nature 470 (7333), 269-273, 2011 | 546 | 2011 |
| Targeting the p53 signaling pathway in cancer therapy–the promises, challenges and perils AH Stegh Expert opinion on therapeutic targets 16 (1), 67-83, 2012 | 231 | 2012 |
| miR-182 integrates apoptosis, growth, and differentiation programs in glioblastoma FM Kouri, LA Hurley, WL Daniel, ES Day, Y Hua, L Hao, CY Peng, ... Genes & development 29 (7), 732-745, 2015 | 224 | 2015 |
| Cancer-associated IDH1 promotes growth and resistance to targeted therapies in the absence of mutation AE Calvert, A Chalastanis, Y Wu, LA Hurley, FM Kouri, Y Bi, M Kachman, ... Cell reports 19 (9), 1858-1873, 2017 | 203 | 2017 |
| Bcl2L12 inhibits post-mitochondrial apoptosis signaling in glioblastoma AH Stegh, H Kim, RM Bachoo, KL Forloney, J Zhang, H Schulze, K Park, ... Genes & development 21 (1), 98-111, 2007 | 184 | 2007 |
| Identification of the cytolinker plectin as a major early in vivo substrate for caspase 8 during CD95-and tumor necrosis factor receptor-mediated apoptosis AH Stegh, H Herrmann, S Lampel, D Weisenberger, K Andrä, M Seper, ... Molecular and Cellular Biology, 2000 | 177 | 2000 |
| Bcl2L12-mediated inhibition of effector caspase-3 and caspase-7 via distinct mechanisms in glioblastoma AH Stegh, S Kesari, JE Mahoney, HT Jenq, KL Forloney, A Protopopov, ... Proceedings of the National Academy of Sciences 105 (31), 10703-10708, 2008 | 169 | 2008 |
| A first-in-human phase 0 clinical study of RNA interference–based spherical nucleic acids in patients with recurrent glioblastoma P Kumthekar, CH Ko, T Paunesku, K Dixit, AM Sonabend, O Bloch, M Tate, ... Science translational medicine 13 (584), eabb3945, 2021 | 156 | 2021 |
| DEDD, a novel death effector domain-containing protein, targeted to the nucleolus AH Stegh, O Schickling, A Ehret, C Scaffidi, C Peterhänsel, TG Hofmann, ... The EMBO journal 17 (20), 5974-5986, 1998 | 154 | 1998 |
| Inactivation of caspase-8 on mitochondria of Bcl-xL-expressing MCF7-Fas cells: role for the bifunctional apoptosis regulator protein AH Stegh, BC Barnhart, J Volkland, A Algeciras-Schimnich, N Ke, ... Journal of Biological Chemistry 277 (6), 4351-4360, 2002 | 136 | 2002 |
| Cancer-associated mutation and beyond: The emerging biology of isocitrate dehydrogenases in human disease S Tommasini-Ghelfi, K Murnan, FM Kouri, AS Mahajan, JL May, AH Stegh Science advances 5 (5), eaaw4543, 2019 | 131 | 2019 |
| Bcl2L13 is a ceramide synthase inhibitor in glioblastoma SA Jensen, AE Calvert, G Volpert, FM Kouri, LA Hurley, JP Luciano, Y Wu, ... Proceedings of the National Academy of Sciences 111 (15), 5682-5687, 2014 | 126 | 2014 |
| Inhibition of DNA damage repair by the CDK4/6 inhibitor palbociclib delays irradiated intracranial atypical teratoid rhabdoid tumor and glioblastoma xenograft regrowth R Hashizume, A Zhang, S Mueller, MD Prados, RR Lulla, S Goldman, ... Neuro-oncology 18 (11), 1519-1528, 2016 | 118 | 2016 |
| Glioma oncoprotein Bcl2L12 inhibits the p53 tumor suppressor AH Stegh, C Brennan, JA Mahoney, KL Forloney, HT Jenq, JP Luciano, ... Genes & development 24 (19), 2194-2204, 2010 | 105 | 2010 |
| Nanotechnology-based precision tools for the detection and treatment of cancer CA Mirkin, TJ Meade, SH Petrosko, AH Stegh Springer, 2015 | 99 | 2015 |
| DEDD regulates degradation of intermediate filaments during apoptosis JC Lee, O Schickling, AH Stegh, RG Oshima, D Dinsdale, GM Cohen, ... The Journal of cell biology 158 (6), 1051-1066, 2002 | 99 | 2002 |
| Beyond effector caspase inhibition: Bcl2L12 neutralizes p53 signaling in glioblastoma AH Stegh, RA DePinho Cell cycle 10 (1), 33-38, 2011 | 88 | 2011 |
Ronald A. DePinhoMD AndersonDirección de correo verificada de mdanderson.org
