| Acyl sulfonamides as potent protease inhibitors of the hepatitis C virus full-Length NS3 (protease-helicase/NTPase): a comparative study of different C-terminals A Johansson, A Poliakov, E Åkerblom, K Wiklund, G Lindeberg, ... Bioorganic & medicinal chemistry 11 (12), 2551-2568, 2003 | 175 | 2003 |
| Ultralarge virtual screening identifies SARS-CoV-2 main protease inhibitors with broad-spectrum activity against coronaviruses A Luttens, H Gullberg, E Abdurakhmanov, DD Vo, D Akaberi, VO Talibov, ... Journal of the American Chemical Society 144 (7), 2905-2920, 2022 | 150 | 2022 |
| Vinyl Sulfide Cyclized Analogues of Angiotensin II with High Affinity and Full Agonist Activity at the AT1 Receptor P Johannesson, G Lindeberg, A Johansson, GV Nikiforovich, A Gogoll, ... Journal of medicinal chemistry 45 (9), 1767-1777, 2002 | 150 | 2002 |
| Exploration of acyl sulfonamides as carboxylic acid replacements in protease inhibitors of the hepatitis C virus full-length NS3 R Rönn, YA Sabnis, T Gossas, E Åkerblom, UH Danielson, A Hallberg, ... Bioorganic & medicinal chemistry 14 (2), 544-559, 2006 | 86 | 2006 |
| Synthesis of novel aryl and heteroaryl acyl sulfonimidamides via Pd-catalyzed carbonylation using a nongaseous precursor SR Borhade, A Sandstrom, PI Arvidsson Organic letters 15 (5), 1056-1059, 2013 | 74 | 2013 |
| Phenylglycine as a novel P2 scaffold in hepatitis C virus NS3 protease inhibitors P Örtqvist, SD Peterson, E Åkerblom, T Gossas, YA Sabnis, R Fransson, ... Bioorganic & medicinal chemistry 15 (3), 1448-1474, 2007 | 63 | 2007 |
| Evaluation of a diverse set of potential P1 carboxylic acid bioisosteres in hepatitis C virus NS3 protease inhibitors R Rönn, T Gossas, YA Sabnis, H Daoud, E Åkerblom, UH Danielson, ... Bioorganic & medicinal chemistry 15 (12), 4057-4068, 2007 | 59 | 2007 |
| Preclinical characterization of acyl sulfonimidamides: potential carboxylic acid bioisosteres with tunable properties SR Borhade, R Svensson, P Brandt, P Artursson, PI Arvidsson, ... ChemMedChem 10 (3), 455-460, 2015 | 54 | 2015 |
| Inhibition of hepatitis C virus NS3 protease activity by product-based peptides is dependent on helicase domain A Johansson, I Hubatsch, E Åkerblom, G Lindeberg, S Winiwarter, ... Bioorganic & medicinal chemistry letters 11 (2), 203-206, 2001 | 50 | 2001 |
| Tetrapeptides as potent protease inhibitors of hepatitis C virus full-length NS3 (protease-helicase/NTPase) A Johansson, A Poliakov, E Åkerblom, G Lindeberg, S Winiwarter, ... Bioorganic & medicinal chemistry 10 (12), 3915-3922, 2002 | 49 | 2002 |
| An improved procedure for N-to C-directed (Inverse) solid-phase peptide synthesis A Johansson, E Åkerblom, K Ersmark, G Lindeberg, A Hallberg Journal of combinatorial chemistry 2 (5), 496-507, 2000 | 48 | 2000 |
| Structure–activity relationships for the selectivity of hepatitis C virus NS3 protease inhibitors A Poliakov, A Johansson, E Åkerblom, K Oscarsson, B Samuelsson, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1672 (1), 51-59, 2004 | 46 | 2004 |
| New developments in the discovery of agents to treat hepatitis C R Ronn, A Sandstrom Current Topics in Medicinal Chemistry 8 (7), 533-562, 2008 | 44 | 2008 |
| Palladium-catalyzed aminocarbonylation in solid-phase peptide synthesis: a method for capping, cyclization, and isotope labeling A Skogh, SD Friis, T Skrydstrup, A Sandström Organic letters 19 (11), 2873-2876, 2017 | 38 | 2017 |
| A straightforward microwave method for rapid synthesis of N-1, C-6 functionalized 3, 5-dichloro-2 (1 H)-pyrazinones J Gising, P Örtqvist, A Sandström, M Larhed Organic & Biomolecular Chemistry 7 (13), 2809-2815, 2009 | 37 | 2009 |
| A straightforward microwave method for rapid synthesis of N-1, C-6 functionalized 3, 5-dichloro-2 (1 H)-pyrazinones J Gising, P Örtqvist, A Sandström, M Larhed Organic & Biomolecular Chemistry 7 (13), 2809-2815, 2009 | 37 | 2009 |
| Small peptides mimicking substance P (1–7) and encompassing a C-terminal amide functionality R Fransson, M Botros, F Nyberg, G Lindeberg, A Sandström, M Hallberg Neuropeptides 42 (1), 31-37, 2008 | 30 | 2008 |
| Effects on protease inhibition by modifying of helicase residues in hepatitis C virus nonstructural protein 3 G Dahl, A Sandström, E Åkerblom, UH Danielson The FEBS Journal 274 (22), 5979-5986, 2007 | 30 | 2007 |
| Resistance profiling of hepatitis C virus protease inhibitors using full-length NS3 G Dahl, A Sandström, E Åkerblom, UH Danielson Antiviral therapy 12 (5), 733-740, 2007 | 29 | 2007 |
| Achiral pyrazinone-based inhibitors of the hepatitis C virus NS3 protease and drug-resistant variants with elongated substituents directed toward the S2 pocket J Gising, AK Belfrage, H Alogheli, A Ehrenberg, E Åkerblom, R Svensson, ... Journal of Medicinal Chemistry 57 (5), 1790-1801, 2014 | 28 | 2014 |
