| The phosphatidylinositol 3-kinase–AKT pathway in human cancer I Vivanco, CL Sawyers Nature Reviews Cancer 2 (7), 489-501, 2002 | 7703 | 2002 |
| Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors IK Mellinghoff, MY Wang, I Vivanco, DA Haas-Kogan, S Zhu, EQ Dia, ... New England Journal of Medicine 353 (19), 2012-2024, 2005 | 1719 | 2005 |
| Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma R Beroukhim, G Getz, L Nghiemphu, J Barretina, T Hsueh, D Linhart, ... Proceedings of the National Academy of Sciences 104 (50), 20007-20012, 2007 | 1235 | 2007 |
| Dual targeting of EGFR can overcome a major drug resistance mutation in mouse models of EGFR mutant lung cancer L Regales, Y Gong, R Shen, E de Stanchina, I Vivanco, A Goel, ... The Journal of clinical investigation 119 (10), 3000-3010, 2009 | 473 | 2009 |
| STEAP: a prostate-specific cell-surface antigen highly expressed in human prostate tumors RS Hubert, I Vivanco, E Chen, S Rastegar, K Leong, SC Mitchell, ... Proceedings of the National Academy of Sciences 96 (25), 14523-14528, 1999 | 470 | 1999 |
| Somatic mutations of the Parkinson's disease–associated gene PARK2 in glioblastoma and other human malignancies S Veeriah, BS Taylor, S Meng, F Fang, E Yilmaz, I Vivanco, ... Nature genetics 42 (1), 77-82, 2010 | 414 | 2010 |
| Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain JC Lee, I Vivanco, R Beroukhim, JHY Huang, WL Feng, RM DeBiasi, ... PLoS medicine 3 (12), e485, 2006 | 410 | 2006 |
| HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability IK Mellinghoff, I Vivanco, A Kwon, C Tran, J Wongvipat, CL Sawyers Cancer cell 6 (5), 517-527, 2004 | 406 | 2004 |
| Differential sensitivity of glioma-versus lung cancer–specific EGFR mutations to EGFR kinase inhibitors I Vivanco, HI Robins, D Rohle, C Campos, C Grommes, PL Nghiemphu, ... Cancer discovery 2 (5), 458-471, 2012 | 365 | 2012 |
| The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers S Veeriah, C Brennan, S Meng, B Singh, JA Fagin, DB Solit, PB Paty, ... Proceedings of the National Academy of Sciences 106 (23), 9435-9440, 2009 | 312 | 2009 |
| Catalytic cleavage of the androgen-regulated TMPRSS2 protease results in its secretion by prostate and prostate cancer epithelia DEH Afar, I Vivanco, RS Hubert, J Kuo, E Chen, DC Saffran, AB Raitano, ... Cancer research 61 (4), 1686-1692, 2001 | 311 | 2001 |
| Mammalian target of rapamycin inhibition promotes response to epidermal growth factor receptor kinase inhibitors in PTEN-deficient and PTEN-intact glioblastoma cells MY Wang, KV Lu, S Zhu, EQ Dia, I Vivanco, GM Shackleford, ... Cancer research 66 (16), 7864-7869, 2006 | 299 | 2006 |
| Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN I Vivanco, N Palaskas, C Tran, SP Finn, G Getz, NJ Kennedy, J Jiao, ... Cancer cell 11 (6), 555-569, 2007 | 282 | 2007 |
| Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death NA Graham, M Tahmasian, B Kohli, E Komisopoulou, M Zhu, I Vivanco, ... Molecular systems biology 8 (1), 589, 2012 | 223 | 2012 |
| Murine cell lines derived from Pten null prostate cancer show the critical role of PTEN in hormone refractory prostate cancer development J Jiao, S Wang, R Qiao, I Vivanco, PA Watson, CL Sawyers, H Wu Cancer research 67 (13), 6083-6091, 2007 | 212 | 2007 |
| The phosphatase and tensin homolog regulates epidermal growth factor receptor (EGFR) inhibitor response by targeting EGFR for degradation I Vivanco, D Rohle, M Versele, A Iwanami, D Kuga, B Oldrini, K Tanaka, ... Proceedings of the National Academy of Sciences 107 (14), 6459-6464, 2010 | 135 | 2010 |
| A kinase-independent function of AKT promotes cancer cell survival I Vivanco, ZC Chen, B Tanos, B Oldrini, WY Hsieh, N Yannuzzi, ... Elife 3, e03751, 2014 | 87 | 2014 |
| Identification of an androgen-dependent enhancer within the prostate stem cell antigen gene A Jain, A Lam, I Vivanco, MF Carey, RE Reiter Molecular Endocrinology 16 (10), 2323-2337, 2002 | 73 | 2002 |
| Epidermal growth factor receptor inhibitors in oncology I Vivanco, IK Mellinghoff Current Opinion in Oncology 22 (6), 573-578, 2010 | 64 | 2010 |
| Targeting molecular addictions in cancer I Vivanco British journal of cancer 111 (11), 2033-2038, 2014 | 53 | 2014 |
