Paul Dobson
Paul Dobson
Scruffy Biotech Ltd
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Citado por
A community-driven global reconstruction of human metabolism
I Thiele, N Swainston, RMT Fleming, A Hoppe, S Sahoo, MK Aurich, ...
Nature biotechnology 31 (5), 419, 2013
A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology
MJ Herrgård, N Swainston, P Dobson, WB Dunn, KY Arga, M Arvas, ...
Nature biotechnology 26 (10), 1155, 2008
Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?
PD Dobson, DB Kell
Nature reviews Drug discovery 7 (3), 205, 2008
Distinguishing enzyme structures from non-enzymes without alignments
PD Dobson, AJ Doig
Journal of molecular biology 330 (4), 771-783, 2003
Mass spectrometry tools and metabolite-specific databases for molecular identification in metabolomics
M Brown, WB Dunn, P Dobson, Y Patel, CL Winder, S Francis-McIntyre, ...
Analyst 134 (7), 1322-1332, 2009
Recon 2.2: from reconstruction to model of human metabolism
N Swainston, K Smallbone, H Hefzi, PD Dobson, J Brewer, M Hanscho, ...
Metabolomics 12 (7), 109, 2016
Predicting enzyme class from protein structure without alignments
PD Dobson, AJ Doig
Journal of molecular biology 345 (1), 187-199, 2005
Pharmaceutical drug transport: the issues and the implications that it is essentially carrier-mediated only
DB Kell, PD Dobson, SG Oliver
Drug discovery today 16 (15-16), 704-714, 2011
The promiscuous binding of pharmaceutical drugs and their transporter-mediated uptake into cells: what we (need to) know and how we can do so
DB Kell, PD Dobson, E Bilsland, SG Oliver
Drug discovery today 18 (5-6), 218-239, 2013
‘Metabolite-likeness’ as a criterion in the design and selection of pharmaceutical drug libraries
PD Dobson, Y Patel, DB Kell
Drug Discovery Today 14 (1-2), 31-40, 2009
Further developments towards a genome-scale metabolic model of yeast
PD Dobson, K Smallbone, D Jameson, E Simeonidis, K Lanthaler, P Pir, ...
BMC Systems Biology 4 (1), 145, 2010
Integration of metabolic databases for the reconstruction of genome-scale metabolic networks
K Radrich, Y Tsuruoka, P Dobson, A Gevorgyan, N Swainston, G Baart, ...
BMC systems biology 4 (1), 114, 2010
Implications of the Dominant Role of Transporters in Drug Uptake by Cells (Supplementary Material)
PD Dobson, K Lanthaler, SG Oliver, DB Kell
Current topics in medicinal chemistry 9 (2), 163-181, 2009
Prediction of protein function in the absence of significant sequence similarity
PD Dobson, YD Cai, BJ Stapley, AJ Doig
Current medicinal chemistry 11 (16), 2135-2142, 2004
Genome-wide assessment of the carriers involved in the cellular uptake of drugs: a model system in yeast
K Lanthaler, E Bilsland, PD Dobson, HJ Moss, P Pir, DB Kell, SG Oliver
BMC biology 9 (1), 70, 2011
Mining metabolites: extracting the yeast metabolome from the literature
C Nobata, PD Dobson, SA Iqbal, P Mendes, J Tsujii, DB Kell, ...
Metabolomics 7 (1), 94-101, 2011
Length preferences and periodicity in β‐strands. Antiparallel edge β‐sheets are more likely to finish in non‐hydrogen bonded rings
S Penel, RG Morrison, PD Dobson, RJ Mortishire‐Smith, AJ Doig
Protein engineering 16 (12), 957-961, 2003
Text mining meets workflow: linking U-Compare with Taverna
Y Kano, P Dobson, M Nakanishi, J Tsujii, S Ananiadou
Bioinformatics 26 (19), 2486-2487, 2010
The cellular uptake of pharmaceutical drugs is mainly carrier-mediated and is thus an issue not so much of biophysics but of systems biology
DB Kell, PD Dobson
Proc Int Beilstein Symposium on Systems Chemistry, 2009
biochem4j: Integrated and extensible biochemical knowledge through graph databases
N Swainston, R Batista-Navarro, P Carbonell, PD Dobson, M Dunstan, ...
PLoS One 12 (7), e0179130, 2017
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