Enzyme evolution: innovation is easy, optimization is complicated MS Newton, VL Arcus, ML Gerth, WM Patrick Current opinion in structural biology 48, 110-116, 2018 | 52 | 2018 |
Rapid bursts and slow declines: on the possible evolutionary trajectories of enzymes MS Newton, VL Arcus, WM Patrick Journal of The Royal Society Interface 12 (107), 20150036, 2015 | 25 | 2015 |
Structural and functional innovations in the real-time evolution of new (βα) 8 barrel enzymes MS Newton, X Guo, A Söderholm, J Näsvall, P Lundström, DI Andersson, ... Proceedings of the National Academy of Sciences 114 (18), 4727-4732, 2017 | 18 | 2017 |
Two-step ligand binding in a (βα) 8 barrel enzyme-substrate-bound structures shed new light on the catalytic cycle of HisA A Söderholm, X Guo, MS Newton, GB Evans, J Näsvall, WM Patrick, ... Journal of Biological Chemistry, jbc. M115. 678086, 2015 | 11 | 2015 |
In Vitro Selection of Peptides and Proteins—Advantages of mRNA Display MS Newton, Y Cabezas-Perusse, CL Tong, B Seelig ACS Synthetic Biology 9 (2), 181-190, 2019 | 8 | 2019 |
Genetic Code Evolution Investigated through the Synthesis and Characterisation of Proteins from Reduced‐Alphabet Libraries MS Newton, DJ Morrone, KH Lee, B Seelig ChemBioChem 20 (6), 846-856, 2019 | 8 | 2019 |
On the Evolution of Catalysis: The changing kinetics of core metabolic enzymes MS Newton University of Otago, 2015 | 3 | 2015 |
Structure and kinetics of indole-3-glycerol phosphate synthase from Pseudomonas aeruginosa: Decarboxylation is not essential for indole formation A Söderholm, MS Newton, WM Patrick, M Selmer Journal of Biological Chemistry 295 (47), 15948-15956, 2020 | | 2020 |