| Total Synthesis and Biological Evaluation of Amaryllidaceae Alkaloids: Narciclasine, e nt-7-Deoxypancratistatin, Regioisomer of 7-Deoxypancratistatin, 10b-e pi … T Hudlicky, U Rinner, D Gonzalez, H Akgun, S Schilling, P Siengalewicz, ... The Journal of Organic Chemistry 67 (25), 8726-8743, 2002 | 228 | 2002 |
| A short chemoenzymatic synthesis of (+)-narciclasine D Gonzalez, T Martinot, T Hudlicky Tetrahedron letters 40 (16), 3077-3080, 1999 | 126 | 1999 |
| Synthesis, Structure, and Biological Evaluation of Novel N- and O-Linked Diinositols BJ Paul, J Willis, TA Martinot, I Ghiviriga, KA Abboud, T Hudlicky Journal of the American Chemical Society 124 (35), 10416-10426, 2002 | 72 | 2002 |
| Artificial genetic systems: exploiting the “aromaticity” formalism to improve the tautomeric ratio for isoguanosine derivatives TA Martinot, SA Benner The Journal of Organic Chemistry 69 (11), 3972-3975, 2004 | 53 | 2004 |
| Discovery of amino-cyclobutarene-derived indoleamine-2, 3-dioxygenase 1 (IDO1) inhibitors for cancer immunotherapy H Zhang, K Liu, Q Pu, A Achab, MJ Ardolino, M Cheng, Y Deng, AC Doty, ... ACS medicinal chemistry letters 10 (11), 1530-1536, 2019 | 40 | 2019 |
| Data-rich experimentation enables palladium-catalyzed couplings of piperidines and five-membered (hetero) aromatic electrophiles AC Sather, TA Martinot Organic Process Research & Development 23 (8), 1725-1739, 2019 | 33 | 2019 |
| Synthesis of the Bis-tetrahydropyran Core of Amphidinol 3 MT Crimmins, TJ Martin, TA Martinot Organic letters 12 (17), 3890-3893, 2010 | 31 | 2010 |
| Discovery and optimization of rationally designed bicyclic inhibitors of human arginase to enhance cancer immunotherapy MJ Mitcheltree, D Li, A Achab, A Beard, K Chakravarthy, M Cheng, H Cho, ... ACS Medicinal Chemistry Letters 11 (4), 582-588, 2020 | 23 | 2020 |
| Novel O-and N-linked inositol oligomers: A new class of unnatural saccharide mimics BJ Paul, TA Martinot, J Willis, T Hudlicky Synthesis 2001 (06), 0952-0956, 2001 | 22 | 2001 |
| Development of a manufacturing process for an HCV protease inhibitor candidate molecule BJ Littler, M Aizenberg, NB Ambhaikar, TA Blythe, TT Curran, ... Organic Process Research & Development 19 (1), 270-283, 2015 | 17 | 2015 |
| Carbamate and N-Pyrimidine Mitigate Amide Hydrolysis: Structure-Based Drug Design of Tetrahydroquinoline IDO1 Inhibitors D Li, Y Deng, A Achab, I Bharathan, BA Hopkins, W Yu, H Zhang, ... ACS medicinal chemistry letters 12 (3), 389-396, 2021 | 16 | 2021 |
| A design of experiments approach to a robust final deprotection and reactive crystallization of IPI-926, a novel hedgehog pathway inhibitor TA Martinot, BC Austad, A Côté, KM Depew, D Genov, L Grenier, J Helble, ... Organic Process Research & Development 19 (11), 1693-1702, 2015 | 13 | 2015 |
| Oxetane promise delivered: discovery of long-acting IDO1 inhibitors suitable for Q3W oral or parenteral dosing D Li, DL Sloman, A Achab, H Zhou, MA McGowan, C White, C Gibeau, ... Journal of Medicinal Chemistry 65 (8), 6001-6016, 2022 | 10 | 2022 |
| Scalable Synthesis of Amaryllidaceae Isocarbostyril Alkaloids from Enantiomerically Pure 7-Azabicyclo [2.2. 1] heptanone Scaffold: Total Synthesis of (+)-7-Deoxypancratistatin G Pandey, R Fernandes, D Dey Synlett 29 (06), 805-809, 2018 | 9 | 2018 |
| Comprehensive strategies to bicyclic prolines: applications in the synthesis of potent arginase inhibitors D Li, H Zhang, TW Lyons, M Lu, A Achab, Q Pu, M Childers, ... ACS Medicinal Chemistry Letters 12 (11), 1678-1688, 2021 | 8 | 2021 |
| Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1H-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson’s Disease DA Candito, V Simov, A Gulati, S Kattar, RW Chau, BT Lapointe, ... Journal of Medicinal Chemistry 65 (24), 16801-16817, 2022 | 7 | 2022 |
| Palladium-Catalyzed Regioselective Heck–Suzuki–Miyaura Cascade Cyclization for the Synthesis of Trisubstituted Arylideneisoquinolinones MS Asgari, R Mirzazadeh, B Larijani, PR Ranjbar, R Rahimi, M Mahdavi Synlett 30 (09), 1073-1076, 2019 | 7 | 2019 |
| Utilization of metabolite identification and structural data to guide design of low-dose IDO1 inhibitors B Hopkins, H Zhang, I Bharathan, D Li, Q Pu, H Zhou, TA Martinot, ... ACS Medicinal Chemistry Letters 12 (9), 1435-1440, 2021 | 6 | 2021 |
| Development of a Zinc-Mediated Approach to a 2,3-cis-Pyrrolidine Arginase Inhibitor TW Lyons, TA Martinot, CQ He, J Qi, G Shao Organic Process Research & Development 24 (8), 1457-1466, 2020 | 6 | 2020 |
| A Ghiviriga I Abboud K A Hudlicky T J BJWJ Paul, T Martinot Am. Chem. Soc 124, 10416, 2002 | 6 | 2002 |
