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David Castillo-Azofeifa
David Castillo-Azofeifa
Senior Scientist at Genentech
Dirección de correo verificada de gene.com
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Lgr5+ telocytes are a signaling source at the intestinal villus tip
K Bahar Halpern, H Massalha, RK Zwick, AE Moor, D Castillo-Azofeifa, ...
Nature communications 11 (1), 1936, 2020
1142020
Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia
KL McKinley, N Stuurman, LA Royer, C Schartner, D Castillo-Azofeifa, ...
Elife 7, e36739, 2018
802018
Induction of ectopic taste buds by SHH reveals the competency and plasticity of adult lingual epithelium
D Castillo, K Seidel, E Salcedo, C Ahn, FJ de Sauvage, OD Klein, ...
Development 141 (15), 2993-3002, 2014
802014
Stress-induced phosphorylation of PACT reduces its interaction with TRBP and leads to PKR activation
M Singh, D Castillo, CV Patel, RC Patel
Biochemistry 50 (21), 4550-4560, 2011
782011
A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage
A Sharir, P Marangoni, R Zilionis, M Wan, T Wald, JK Hu, K Kawaguchi, ...
Nature cell biology 21 (9), 1102-1112, 2019
772019
Sonic hedgehog from both nerves and epithelium is a key trophic factor for taste bud maintenance
D Castillo-Azofeifa, JT Losacco, E Salcedo, EJ Golden, TE Finger, ...
Development 144 (17), 3054-3065, 2017
672017
Atoh1+ secretory progenitors possess renewal capacity independent of Lgr5+ cells during colonic regeneration
D Castillo‐Azofeifa, EN Fazio, R Nattiv, HJ Good, T Wald, MA Pest, ...
The EMBO journal 38 (4), e99984, 2019
652019
Epithelial WNT ligands are essential drivers of intestinal stem cell activation
WY Zou, SE Blutt, XL Zeng, MS Chen, YH Lo, D Castillo-Azofeifa, ...
Cell reports 22 (4), 1003-1015, 2018
592018
SOX2 regulation by hedgehog signaling controls adult lingual epithelium homeostasis
D Castillo-Azofeifa, K Seidel, L Gross, EJ Golden, B Jacquez, OD Klein, ...
Development 145 (14), dev164889, 2018
272018
Tools and concepts for interrogating and defining cellular identity
KL McKinley, D Castillo-Azofeifa, OD Klein
Cell Stem Cell 26 (5), 632-656, 2020
242020
Cellular shape reinforces niche to stem cell signaling in the small intestine
N Pentinmikko, R Lozano, S Scharaw, S Andersson, JI Englund, ...
Science advances 8 (41), eabm1847, 2022
142022
Contribution of the two dsRBM motifs to the double‐stranded RNA binding and protein interactions of PACT
E Chukwurah, V Willingham, M Singh, D Castillo‐Azofeifa, RC Patel
Journal of cellular biochemistry 119 (4), 3598-3607, 2018
112018
Lgr5+ telocytes are a signaling hub at the intestinal villus tip
KB Halpern, H Massalha, RK Zwick, AE Moor, D Castillo-Azofeifa, ...
bioRxiv, 850909, 2019
62019
Intracellular pH dynamics regulates intestinal stem cell lineage specification
Y Liu, E Reyes, D Castillo-Azofeifa, OD Klein, T Nystul, DL Barber
Nature communications 14 (1), 3745, 2023
52023
Epithelial TNF controls cell differentiation and CFTR activity to maintain intestinal mucin homeostasis
EA Reyes, D Castillo-Azofeifa, J Rispal, T Wald, RK Zwick, B Palikuqi, ...
The Journal of clinical investigation 133 (20), 2023
42023
A DLG1-ARHGAP31-CDC42 axis is essential for the intestinal stem cell response to fluctuating niche Wnt signaling
D Castillo-Azofeifa, T Wald, EA Reyes, A Gallagher, J Schanin, S Vlachos, ...
Cell Stem Cell 30 (2), 188-206. e6, 2023
42023
430-Epithelial-Secreted WNT Ligands are Essential Drivers of Intestinal Stem Cell Response to Virus-Induced Villus Damage
WY Zou, SE Blutt, XL Zeng, MS Chen, YH Lo, D Castillo-Azofeifa, OD Kein, ...
Gastroenterology 154 (6), S-96, 2018
22018
CHRONIC IFNΓ-DRIVEN INFLAMMATION IMPAIRS INTESTINAL TOLERANCE AND REGENERATION IN AGING
D Castillo-Azofeifa
Innovation in Aging 7 (Suppl 1), 260, 2023
2023
Molecular Genetic Lineage Tracing of Taste Bud Cells in Adult Mice.
L Gross, JK Scott, DC Azofeifa, D Gaillard, LA Barlow
CHEMICAL SENSES 43 (4), E58-E58, 2018
2018
A136 THE ROLE OF KERATIN-19 POSITIVE STEM CELLS IN COLONIC REGENERATION POST COLITIS
E Fazio, R Nattiv, D Castillo-Azofeifa, Y Nusse, J SCHANIN, O Klein, ...
Journal of the Canadian Association of Gastroenterology 1 (suppl_1), 236-236, 2018
2018
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20