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Kelly R. Bales
Kelly R. Bales
Voyager Therapeutics
Verified email at vygr.com
Title
Cited by
Cited by
Year
Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease
RB DeMattos, KR Bales, DJ Cummins, JC Dodart, SM Paul, DM Holtzman
Proceedings of the National Academy of Sciences 98 (15), 8850-8855, 2001
17422001
Synaptic activity regulates interstitial fluid amyloid-β levels in vivo
JR Cirrito, KA Yamada, MB Finn, RS Sloviter, KR Bales, PC May, ...
Neuron 48 (6), 913-922, 2005
14092005
Human apoE isoforms differentially regulate brain amyloid-β peptide clearance
JM Castellano, J Kim, FR Stewart, H Jiang, RB DeMattos, BW Patterson, ...
Science translational medicine 3 (89), 89ra57-89ra57, 2011
13852011
Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model
JC Dodart, KR Bales, KS Gannon, SJ Greene, RB DeMattos, C Mathis, ...
Nature neuroscience 5 (5), 452-457, 2002
12362002
Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease
DM Holtzman, KR Bales, T Tenkova, AM Fagan, M Parsadanian, ...
Proceedings of the National Academy of Sciences 97 (6), 2892-2897, 2000
11352000
Lack of apolipoprotein E dramatically reduces amyloid β-peptide deposition
KR Bales, T Verina, RC Dodel, Y Du, L Altstiel, M Bender, P Hyslop, ...
Nature genetics 17 (3), 263-264, 1997
10801997
Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease
Y Du, Z Ma, S Lin, RC Dodel, F Gao, KR Bales, LC Triarhou, E Chernet, ...
Proceedings of the National Academy of Sciences 98 (25), 14669-14674, 2001
9582001
P-glycoprotein deficiency at the blood-brain barrier increases amyloid-β deposition in an Alzheimer disease mouse model
JR Cirrito, R Deane, AM Fagan, ML Spinner, M Parsadanian, MB Finn, ...
The Journal of clinical investigation 115 (11), 3285-3290, 2005
7632005
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein
OM Andersen, J Reiche, V Schmidt, M Gotthardt, R Spoelgen, J Behlke, ...
Proceedings of the National Academy of Sciences 102 (38), 13461-13466, 2005
7572005
Brain to plasma amyloid-β efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease
RB DeMattos, KR Bales, DJ Cummins, SM Paul, DM Holtzman
science 295 (5563), 2264-2267, 2002
7442002
Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-β peptides
M Koistinaho, S Lin, XIN Wu, M Esterman, D Koger, J Hanson, R Higgs, ...
Nature medicine 10 (7), 719-726, 2004
7002004
Apolipoprotein E is essential for amyloid deposition in the APPV717F transgenic mouse model of Alzheimer's disease
KR Bales, T Verina, DJ Cummins, Y Du, RC Dodel, J Saura, CE Fishman, ...
Proceedings of the National Academy of Sciences 96 (26), 15233-15238, 1999
6361999
In vivo assessment of brain interstitial fluid with microdialysis reveals plaque-associated changes in amyloid-β metabolism and half-life
JR Cirrito, PC May, MA O'Dell, JW Taylor, M Parsadanian, JW Cramer, ...
Journal of Neuroscience 23 (26), 8844-8853, 2003
5702003
ApoE and clusterin cooperatively suppress Aβ levels and deposition: evidence that ApoE regulates extracellular Aβ metabolism in vivo
RB DeMattos, JR Cirrito, M Parsadanian, PC May, MA O'Dell, JW Taylor, ...
Neuron 41 (2), 193-202, 2004
5482004
Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease
SE Wahrle, H Jiang, M Parsadanian, J Kim, A Li, A Knoten, S Jain, ...
The Journal of clinical investigation 118 (2), 671-682, 2008
4432008
Expression of human apolipoprotein E reduces amyloid-β deposition in a mouse model of Alzheimer's disease
DM Holtzman, KR Bales, S Wu, P Bhat, M Parsadanian, AM Fagan, ...
The Journal of clinical investigation 103 (6), R15-R21, 1999
4261999
Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of …
MM Racke, LI Boone, DL Hepburn, M Parsadainian, MT Bryan, DK Ness, ...
Journal of Neuroscience 25 (3), 629-636, 2005
4202005
Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model
DM Holtzman, AM Fagan, B Mackey, T Tenkova, L Sartorius, SM Paul, ...
Annals of Neurology: Official Journal of the American Neurological …, 2000
4012000
Deletion of Abca1 increases Aβ deposition in the PDAPP transgenic mouse model of Alzheimer disease
SE Wahrle, H Jiang, M Parsadanian, RE Hartman, KR Bales, SM Paul, ...
Journal of Biological Chemistry 280 (52), 43236-43242, 2005
3882005
Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease
RB DeMattos, MA O'dell, M Parsadanian, JW Taylor, JAK Harmony, ...
Proceedings of the National Academy of Sciences 99 (16), 10843-10848, 2002
3722002
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