Core circadian clock genes regulate leukemia stem cells in AML RV Puram, MS Kowalczyk, CG de Boer, RK Schneider, PG Miller, ... Cell 165 (2), 303-316, 2016 | 240 | 2016 |
A molecular hypothesis to explain direct and inverse co-morbidities between Alzheimer’s Disease, Glioblastoma and Lung cancer J Sánchez-Valle, H Tejero, K Ibáñez, JL Portero, M Krallinger, ... Scientific reports 7 (1), 1-12, 2017 | 101 | 2017 |
Treatment of pancreatic cancer patient–derived xenograft panel with metabolic inhibitors reveals efficacy of phenformin NV Rajeshkumar, S Yabuuchi, SG Pai, E De Oliveira, JJ Kamphorst, ... Clinical Cancer Research 23 (18), 5639-5647, 2017 | 96 | 2017 |
Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state D Cerezo-Wallis, M Contreras-Alcalde, K Troulé, X Catena, C Mucientes, ... Nature medicine 26 (12), 1865-1877, 2020 | 90 | 2020 |
PanDrugs: a novel method to prioritize anticancer drug treatments according to individual genomic data E Piñeiro-Yáñez, M Reboiro-Jato, G Gómez-López, J Perales-Patón, ... Genome medicine 10, 1-11, 2018 | 81 | 2018 |
Extinction of hepatitis C virus by ribavirin in hepatoma cells involves lethal mutagenesis AM Ortega-Prieto, J Sheldon, A Grande-Pérez, H Tejero, J Gregori, J Quer, ... PloS one 8 (8), e71039, 2013 | 81 | 2013 |
Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections C Perales, R Agudo, H Tejero, SC Manrubia, E Domingo PLoS pathogens 5 (11), e1000658, 2009 | 81 | 2009 |
Transcriptomic metaanalyses of autistic brains reveals shared gene expression and biological pathway abnormalities with cancer J Forés-Martos, F Catalá-López, J Sánchez-Valle, K Ibáñez, H Tejero, ... Molecular autism 10, 1-16, 2019 | 46 | 2019 |
Interpreting molecular similarity between patients as a determinant of disease comorbidity relationships J Sánchez-Valle, H Tejero, JM Fernández, D Juan, B Urda-García, ... Nature Communications 11 (1), 2854, 2020 | 41 | 2020 |
Theories of lethal mutagenesis: from error catastrophe to lethal defection H Tejero, F Montero, JC Nuño Quasispecies: From Theory to Experimental Systems, 161-179, 2016 | 40 | 2016 |
The relationship between the error catastrophe, survival of the flattest, and natural selection H Tejero, A Marín, F Montero BMC evolutionary biology 11, 1-12, 2011 | 38 | 2011 |
Mutagenesis-mediated virus extinction: virus-dependent effect of viral load on sensitivity to lethal defection H Moreno, H Tejero, JC De la Torre, E Domingo, V Martin PloS one 7 (3), e32550, 2012 | 31 | 2012 |
Effect of lethality on the extinction and on the error threshold of quasispecies H Tejero, A Marín, F Montero Journal of theoretical biology 262 (4), 733-741, 2010 | 30 | 2010 |
Whole exome sequencing identifies PLEC, EXO5 and DNAH7 as novel susceptibility genes in testicular cancer B Paumard‐Hernández, O Calvete, L Inglada Pérez, H Tejero, ... International journal of cancer 143 (8), 1954-1962, 2018 | 27 | 2018 |
Targeted Sequencing Reveals Low-Frequency Variants in EPHA Genes as Markers of Paclitaxel-Induced Peripheral Neuropathy M Apellániz-Ruiz, H Tejero, L Inglada-Pérez, L Sánchez-Barroso, ... Clinical Cancer Research 23 (5), 1227-1235, 2017 | 20 | 2017 |
Activation of the integrated stress response is a vulnerability for multidrug‐resistant FBXW7‐deficient cells L Sanchez‐Burgos, B Navarro‐González, S García‐Martín, O Sirozh, ... EMBO Molecular Medicine 14 (9), e15855, 2022 | 19 | 2022 |
Fatty acids homeostasis during fasting predicts protection from chemotherapy toxicity M Barradas, A Plaza, G Colmenarejo, I Lázaro, LF Costa-Machado, ... Nature Communications 13 (1), 5677, 2022 | 16 | 2022 |
Pancreas cancer precision treatment using avatar mice from a bioinformatics perspective J Perales-Patón, E Piñeiro-Yañez, H Tejero, PP López-Casas, M Hidalgo, ... Public health genomics 20 (2), 81-91, 2017 | 13 | 2017 |
Nanobodies targeting ABCC3 for immunotargeted applications in glioblastoma E Ruiz-López, I Jovčevska, R González-Gómez, H Tejero, F Al-Shahrour, ... Scientific Reports 12 (1), 22581, 2022 | 11 | 2022 |
vulcanSpot: a tool to prioritize therapeutic vulnerabilities in cancer J Perales-Patón, T Di Domenico, C Fustero-Torre, E Piñeiro-Yáñez, ... Bioinformatics 35 (22), 4846-4848, 2019 | 10 | 2019 |