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Michael Karpusas
Michael Karpusas
Professor of Biophysics, Agricultural University of Athens
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Structural and functional differences between glycosylated and non-glycosylated forms of human interferon-β (IFN-β)
L Runkel, W Meier, RB Pepinsky, M Karpusas, A Whitty, K Kimball, ...
Pharmaceutical research 15, 641-649, 1998
4141998
2 Å crystal structure of an extracellular fragment of human CD40 ligand
M Karpusas, YM Hsu, J Wang, J Thompson, S Lederman, L Chess, ...
Structure 3 (10), 1031-1039, 1995
3311995
The crystal structure of human interferon β at 2.2-Å resolution
M Karpusas, M Nolte, CB Benton, W Meier, WN Lipscomb, S Goelz
Proceedings of the National Academy of Sciences 94 (22), 11813-11818, 1997
3291997
Hydrophobic packing in T4 Lysozyme probed by cavity-filling mutants
BWM M Karpusas, WA Baase, M Matsumura
Proceedings of the National Academy of Sciences, 1989
2171989
Crystal structure of extracellular human BAFF, a TNF family member that stimulates B lymphocytes
M Karpusas, TG Cachero, F Qian, A Boriack-Sjodin, C Mullen, K Strauch, ...
Journal of molecular biology 315 (5), 1145-1154, 2002
1762002
Proposed mechanism for the condensation reaction of citrate synthase: 1.9-. ANG. structure of the ternary complex with oxaloacetate and carboxymethyl coenzyme A
M Karpusas, B Branchaud, SJ Remington
Biochemistry 29 (9), 2213-2219, 1990
1651990
The structure of human interferon-β: implications for activity
M Karpusas, A Whitty, L Runkel, P Hochman
Cellular and Molecular Life Sciences CMLS 54, 1203-1216, 1998
1641998
The crystal structure of an N-terminal two-domain fragment of vascular cell adhesion molecule 1 (VCAM-1): a cyclic peptide based on the domain 1 CD loop can inhibit VCAM-1 …
JH Wang, RB Pepinsky, T Stehle, J Liu, M Karpusas, B Browning, ...
Proceedings of the National Academy of Sciences 92 (12), 5714-5718, 1995
1561995
Systematic mutational mapping of sites on human interferon-β-1a that are important for receptor binding and functional activity
L Runkel, C deDios, M Karpusas, M Betzenhauser, C Muldowney, ...
Biochemistry 39 (10), 2538-2551, 2000
1142000
The three-dimensional structure of a class I major histocompatibility complex molecule missing the alpha 3 domain of the heavy chain.
EJ Collins, DN Garboczi, MN Karpusas, DC Wiley
Proceedings of the National Academy of Sciences 92 (4), 1218-1221, 1995
1011995
The role of polar interactions in the molecular recognition of CD40L with its receptor CD40
J Singh, E Garber, HV Vlijmen, M Karpusas, YM Hsu, Z Zheng, D Thomas, ...
Protein science 7 (5), 1124-1135, 1998
971998
Crystal structure of the α1β1 integrin I-domain: insights into integrin I-domain function
M Nolte, RB Pepinsky, SY Venyaminov, V Koteliansky, PJ Gotwals, ...
FEBS letters 452 (3), 379-385, 1999
931999
Antibodies to VLA-1
PD Lyne, EA Garber, JW Saldanha, M Karpusas
US Patent 7,358,054, 2008
852008
Analysis of imatinib and sorafenib binding to p38α compared with c-Abl and b-Raf provides structural insights for understanding the selectivity of inhibitors targeting the DFG …
HV Namboodiri, M Bukhtiyarova, J Ramcharan, M Karpusas, Y Lee, ...
Biochemistry 49 (17), 3611-3618, 2010
822010
1.9-. ANG. Structures of ternary complexes of citrate synthase with D-and L-malate: mechanistic implications
M Karpusas, D Holland, SJ Remington
Biochemistry 30 (24), 6024-6031, 1991
801991
Structure of CD40 ligand in complex with the Fab fragment of a neutralizing humanized antibody
M Karpusas, J Lucci, J Ferrant, C Benjamin, FR Taylor, K Strauch, ...
Structure 9 (4), 321-329, 2001
692001
Prednisolone exerts late mitogenic and biphasic effects on resistant acute lymphoblastic leukemia cells: Relation to early gene expression
GI Lambrou, S Vlahopoulos, C Papathanasiou, M Papanikolaou, ...
Leukemia research 33 (12), 1684-1695, 2009
672009
Improved expression, purification, and crystallization of p38α MAP kinase
M Bukhtiyarova, K Northrop, X Chai, D Casper, M Karpusas, E Springman
Protein expression and purification 37 (1), 154-161, 2004
572004
Crystal structure of an open conformation of citrate synthase from chicken heart at 2.8-. ANG. resolution
DI Liao, M Karpusas, SJ Remington
Biochemistry 30 (24), 6031-6036, 1991
551991
Substitution of Ser for Arg-443 in the regulatory domain of human housekeeping (GLUD1) glutamate dehydrogenase virtually abolishes basal activity and markedly alters the …
I Zaganas, C Spanaki, M Karpusas, A Plaitakis
Journal of Biological Chemistry 277 (48), 46552-46558, 2002
492002
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Artículos 1–20