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Jason M. Torres
Jason M. Torres
Nuffield Department of Population Health, University of Oxford
Dirección de correo verificada de ndph.ox.ac.uk - Página principal
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Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
A Mahajan, D Taliun, M Thurner, NR Robertson, JM Torres, NW Rayner, ...
Nature genetics 50 (11), 1505-1513, 2018
15522018
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics
AN Barbeira, SP Dickinson, R Bonazzola, J Zheng, HE Wheeler, ...
Nature communications 9 (1), 1825, 2018
8432018
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
A Mahajan, CN Spracklen, W Zhang, MCY Ng, LE Petty, H Kitajima, ...
Nature genetics 54 (5), 560-572, 2022
2822022
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls
J Flannick, JM Mercader, C Fuchsberger, MS Udler, A Mahajan, J Wessel, ...
Nature 570 (7759), 71-76, 2019
2802019
Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes
AR Majithia, J Flannick, P Shahinian, M Guo, MA Bray, P Fontanillas, ...
Proceedings of the National Academy of Sciences 111 (36), 13127-13132, 2014
1762014
Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity
P Akbari, A Gilani, O Sosina, JA Kosmicki, L Khrimian, YY Fang, ...
Science 373 (6550), eabf8683, 2021
1612021
Integration of human pancreatic islet genomic data refines regulatory mechanisms at type 2 diabetes susceptibility loci
M Thurner, M Van De Bunt, JM Torres, A Mahajan, V Nylander, ...
Elife 7, e31977, 2018
1232018
Cross-tissue and tissue-specific eQTLs: partitioning the heritability of a complex trait
JM Torres, ER Gamazon, EJ Parra, JE Below, A Valladares-Salgado, ...
The American Journal of Human Genetics 95 (5), 521-534, 2014
962014
Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects and tissue-specific enrichment of eQTLs
JE Below, EJ Parra, ER Gamazon, J Torres, S Krithika, S Candille, Y Lu, ...
Scientific reports 6 (1), 19429, 2016
852016
MetaXcan: summary statistics based gene-level association method infers accurate PrediXcan results
A Barbeira, KP Shah, JM Torres, HE Wheeler, ES Torstenson, T Edwards, ...
BioRxiv, 045260, 2016
702016
TIGER: The gene expression regulatory variation landscape of human pancreatic islets
L Alonso, A Piron, I Morán, M Guindo-Martínez, S Bonàs-Guarch, G Atla, ...
Cell reports 37 (2), 2021
512021
Integrating tissue specific mechanisms into GWAS summary results
AN Barbeira, SP Dickinson, JM Torres, ES Torstenson, J Zheng, ...
BioRxiv, 045260, 2017
412017
Developing a network view of type 2 diabetes risk pathways through integration of genetic, genomic and functional data
J Fernández-Tajes, KJ Gaulton, M van de Bunt, J Torres, M Thurner, ...
Genome Medicine 11, 1-14, 2019
402019
Genome wide association studies for diabetes: perspective on results and challenges.
JM Torres, NJ Cox, LH Philipson
Pediatric diabetes 14 (2), 2013
392013
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics. Nat Commun. 2018; 9 (1): 1825
AN Barbeira, SP Dickinson, R Bonazzola, J Zheng, HE Wheeler, ...
Epub 2018/05/10. https://doi. org/10.1038/s41467-018-03621-1 PMID: 29739930, 0
38
Deep learning models predict regulatory variants in pancreatic islets and refine type 2 diabetes association signals
A Wesolowska-Andersen, G Zhuo Yu, V Nylander, F Abaitua, M Thurner, ...
Elife 9, e51503, 2020
342020
A multi-tissue transcriptome analysis of human metabolites guides interpretability of associations based on multi-SNP models for gene expression
A Ndungu, A Payne, JM Torres, M van de Bunt, MI McCarthy
The American Journal of Human Genetics 106 (2), 188-201, 2020
332020
Inter-ethnic differences in lymphocyte sensitivity to glucocorticoids reflect variation in transcriptional response
JC Maranville, SS Baxter, JM Torres, A Di Rienzo
The pharmacogenomics journal 13 (2), 121-129, 2013
322013
Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
A Mahajan, CN Spracklen, W Zhang, MCY Ng, LE Petty, H Kitajima, ...
MedRxiv, 2020.09. 22.20198937, 2020
312020
Broad Genomics Platform; DiscovEHR Collaboration; CHARGE; LuCamp; ProDiGY; GoT2D; ESP; SIGMA-T2D; T2D-GENES
J Flannick, JM Mercader, C Fuchsberger, MS Udler, A Mahajan, J Wessel, ...
AMP-T2D-GENES. Exome sequencing of 20,791 cases of type 2 diabetes and 24 …, 2019
302019
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