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José Luis Pérez Gracia
José Luis Pérez Gracia
Medical Oncologist. Professor of Medicine. Clinica Universidad de Navarra
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Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial
RS Herbst, P Baas, DW Kim, E Felip, JL Pérez-Gracia, JY Han, J Molina, ...
The Lancet 387 (10027), 1540-1550, 2016
65562016
Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm …
JE Rosenberg, J Hoffman-Censits, T Powles, MS Van Der Heijden, ...
The Lancet 387 (10031), 1909-1920, 2016
36592016
Atezolizumab as first-line treatment in cisplatin-ineligible patients with locally advanced and metastatic urothelial carcinoma: a single-arm, multicentre, phase 2 trial
AV Balar, MD Galsky, JE Rosenberg, T Powles, DP Petrylak, J Bellmunt, ...
The Lancet 389 (10064), 67-76, 2017
20582017
A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C
B Sangro, C Gomez-Martin, M de la Mata, M Iñarrairaegui, E Garralda, ...
Journal of hepatology 59 (1), 81-88, 2013
10212013
Cytokines in clinical cancer immunotherapy
P Berraondo, MF Sanmamed, MC Ochoa, I Etxeberria, MA Aznar, ...
British journal of cancer 120 (1), 6-15, 2019
9362019
Evolving synergistic combinations of targeted immunotherapies to combat cancer
I Melero, DM Berman, MA Aznar, AJ Korman, JL Perez-Gracia, J Haanen
Nature Reviews Cancer 15 (8), 457-472, 2015
7072015
Direct effects of type I interferons on cells of the immune system
S Hervas-Stubbs, JL Perez-Gracia, A Rouzaut, MF Sanmamed, A Le Bon, ...
Clinical Cancer Research 17 (9), 2619-2627, 2011
6232011
Neoadjuvant nivolumab modifies the tumor immune microenvironment in resectable glioblastoma
KA Schalper, ME Rodriguez-Ruiz, R Diez-Valle, A López-Janeiro, ...
Nature medicine 25 (3), 470-476, 2019
5262019
CXCR1 and CXCR2 chemokine receptor agonists produced by tumors induce neutrophil extracellular traps that interfere with immune cytotoxicity
Á Teijeira, S Garasa, M Gato, C Alfaro, I Migueliz, A Cirella, C de Andrea, ...
Immunity 52 (5), 856-871. e8, 2020
4632020
Changes in serum interleukin-8 (IL-8) levels reflect and predict response to anti-PD-1 treatment in melanoma and non-small-cell lung cancer patients
MF Sanmamed, JL Perez-Gracia, KA Schalper, JP Fusco, A Gonzalez, ...
Annals of Oncology 28 (8), 1988-1995, 2017
3882017
Tumor-produced interleukin-8 attracts human myeloid-derived suppressor cells and elicits extrusion of neutrophil extracellular traps (NETs)
C Alfaro, A Teijeira, C Oñate, G Perez, MF Sanmamed, MP Andueza, ...
Clinical Cancer Research 22 (15), 3924-3936, 2016
3612016
Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy
E Perez-Ruiz, L Minute, I Otano, M Alvarez, MC Ochoa, V Belsue, ...
Nature 569 (7756), 428-432, 2019
3552019
Elevated serum interleukin-8 is associated with enhanced intratumor neutrophils and reduced clinical benefit of immune-checkpoint inhibitors
KA Schalper, M Carleton, M Zhou, T Chen, Y Feng, SP Huang, AM Walsh, ...
Nature medicine 26 (5), 688-692, 2020
3362020
Interleukin-8 in cancer pathogenesis, treatment and follow-up
C Alfaro, MF Sanmamed, ME Rodríguez-Ruiz, Á Teijeira, C Oñate, ...
Cancer treatment reviews 60, 24-31, 2017
3142017
Immunomodulatory activity of nivolumab in metastatic renal cell carcinoma
TK Choueiri, MN Fishman, B Escudier, DF McDermott, CG Drake, ...
Clinical Cancer Research 22 (22), 5461-5471, 2016
2772016
Quantitative Cell-Free Circulating BRAFV600E Mutation Analysis by Use of Droplet Digital PCR in the Follow-up of Patients with Melanoma Being Treated with …
MF Sanmamed, S Fernández-Landázuri, C Rodríguez, R Zárate, ...
Clinical chemistry 61 (1), 297-304, 2015
2732015
Antigen cross-presentation and T-cell cross-priming in cancer immunology and immunotherapy
AR Sánchez-Paulete, A Teijeira, FJ Cueto, S Garasa, JL Pérez-Gracia, ...
Annals of Oncology 28, xii44-xii55, 2017
2562017
Agonists of co-stimulation in cancer immunotherapy directed against CD137, OX40, GITR, CD27, CD28, and ICOS
MF Sanmamed, F Pastor, A Rodriguez, JL Perez-Gracia, ...
Seminars in oncology 42 (4), 640-655, 2015
2552015
Expression analysis and significance of PD-1, LAG-3, and TIM-3 in human non–small cell lung cancer using spatially resolved and multiparametric single-cell analysis
I Datar, MF Sanmamed, J Wang, BS Henick, J Choi, T Badri, W Dong, ...
Clinical Cancer Research 25 (15), 4663-4673, 2019
2522019
Serum interleukin-8 reflects tumor burden and treatment response across malignancies of multiple tissue origins
MF Sanmamed, O Carranza-Rua, C Alfaro, C Onate, S Martín-Algarra, ...
Clinical Cancer Research 20 (22), 5697-5707, 2014
2382014
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