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Rubén Corpas, PhD
Rubén Corpas, PhD
ORYZON GENOMICS. Preclinical Scientist, Drug Development Department.
Dirección de correo verificada de oryzon.com - Página principal
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The pleiotropic neuroprotective effects of resveratrol in cognitive decline and Alzheimer’s disease pathology: From antioxidant to epigenetic therapy
C Grinan-Ferre, A Bellver-Sanchis, V Izquierdo, R Corpas, J Roig-Soriano, ...
Ageing research reviews 67, 101271, 2021
1472021
Oxidative stress is a central target for physical exercise neuroprotection against pathological brain aging
Y García-Mesa, S Colie, R Corpas, R Cristòfol, F Comellas, AR Nebreda, ...
Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2016
1412016
Long-term exercise training improves memory in middle-aged men and modulates peripheral levels of BDNF and Cathepsin B
A De la Rosa, E Solana, R Corpas, D Bartrés-Faz, M Pallàs, J Vina, ...
Scientific reports 9 (1), 3337, 2019
1312019
Resveratrol induces brain resilience against Alzheimer neurodegeneration through proteostasis enhancement
R Corpas, C Griñán-Ferré, E Rodríguez-Farré, M Pallàs, C Sanfeliu
Molecular Neurobiology 56, 1502-1516, 2019
1312019
Neurons from senescence‐accelerated SAMP8 mice are protected against frailty by the sirtuin 1 promoting agents melatonin and resveratrol
R Cristofol, D Porquet, R Corpas, A Coto‐Montes, J Serret, A Camins, ...
Journal of pineal research 52 (3), 271-281, 2012
1102012
Monomeric C-reactive protein-a key molecule driving development of Alzheimer’s disease associated with brain ischaemia?
M Slevin, S Matou, Y Zeinolabediny, R Corpas, R Weston, D Liu, E Boras, ...
Scientific reports 5 (1), 1-21, 2015
1082015
SIRT1 overexpression in mouse hippocampus induces cognitive enhancement through proteostatic and neurotrophic mechanisms
R Corpas, S Revilla, S Ursulet, M Castro-Freire, P Kaliman, V Petegnief, ...
Molecular neurobiology 54, 5604-5619, 2017
1072017
Neuron–astrocyte signaling is preserved in the aging brain
M Gómez‐Gonzalo, M Martin‐Fernandez, R Martínez‐Murillo, S Mederos, ...
Glia 65 (4), 569-580, 2017
1072017
Environmental enrichment improves cognitive deficits, AD hallmarks and epigenetic alterations presented in 5xFAD mouse model
C Griñán-Ferré, V Izquierdo, E Otero, D Puigoriol-Illamola, R Corpas, ...
Frontiers in Cellular Neuroscience 12, 224, 2018
902018
Understanding Epigenetics in the Neurodegeneration of Alzheimer’s Disease: SAMP8 Mouse Model
C Griñán-Ferré, R Corpas, D Puigoriol-Illamola, V Palomera-Ávalos, ...
Journal of Alzheimer's Disease 62 (3), 943-963, 2018
742018
Melatonin induces mechanisms of brain resilience against neurodegeneration
R Corpas, C Griñán‐Ferré, V Palomera‐Ávalos, D Porquet, ...
Journal of Pineal Research 65 (4), e12515, 2018
702018
Pharmacological inhibition of soluble epoxide hydrolase as a new therapy for Alzheimer’s disease
C Griñán-Ferré, S Codony, E Pujol, J Yang, R Leiva, C Escolano, ...
Neurotherapeutics 17, 1825-1835, 2020
652020
Neuronal p38α mediates synaptic and cognitive dysfunction in an Alzheimer’s mouse model by controlling β-amyloid production
S Colié, S Sarroca, R Palenzuela, I Garcia, A Matheu, R Corpas, CG Dotti, ...
Scientific reports 7 (1), 45306, 2017
452017
HIV-1 matrix protein p17 misfolding forms toxic amyloidogenic assemblies that induce neurocognitive disorders
Y Zeinolabediny, F Caccuri, L Colombo, F Morelli, M Romeo, A Rossi, ...
Scientific reports 7 (1), 10313, 2017
402017
Resveratrol confers neuroprotection against high-fat diet in a mouse model of Alzheimer's disease via modulation of proteolytic mechanisms
S Sarroca, A Gatius, E Rodríguez-Farré, D Vilchez, M Pallàs, ...
The Journal of nutritional biochemistry 89, 108569, 2021
352021
In vitro caloric restriction induces protective genes and functional rejuvenation in senescent SAMP8 astrocytes
S García‐Matas, RK Paul, P Molina‐Martínez, H Palacios, VM Gutierrez, ...
Aging Cell 14 (3), 334-344, 2015
262015
Monomeric C-reactive protein localized in the cerebral tissue of damaged vascular brain regions is associated with neuro-inflammation and neurodegeneration-an …
RS Al-Baradie, S Pu, D Liu, Y Zeinolabediny, G Ferris, C Sanfeli, ...
Frontiers in Immunology 12, 644213, 2021
212021
From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis
S Codony, C Calvó-Tusell, E Valverde, S Osuna, C Morisseau, MI Loza, ...
Journal of medicinal chemistry 64 (9), 5429-5446, 2021
192021
Antibody protection against long-term memory loss induced by monomeric c-reactive protein in a mouse model of dementia
E García-Lara, S Aguirre, N Clotet, X Sawkulycz, C Bartra, ...
Biomedicines 9 (7), 828, 2021
162021
Peripheral maintenance of the axis SIRT1-SIRT3 at youth level may contribute to brain resilience in middle-aged amateur rugby players
R Corpas, E Solana, A De la Rosa, S Sarroca, C Griñán-Ferré, M Oriol, ...
Frontiers in Aging Neuroscience 11, 457801, 2019
142019
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