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Paul H. Weinreb
Paul H. Weinreb
Dirección de correo verificada de biogen.com
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The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease
J Sevigny, P Chiao, T Bussière, PH Weinreb, L Williams, M Maier, ...
Nature 537 (7618), 50-56, 2016
28822016
NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded
PH Weinreb, W Zhen, AW Poon, KA Conway, PT Lansbury
Biochemistry 35 (43), 13709-13715, 1996
19281996
Characterization of Sfp, a Bacillus subtilis Phosphopantetheinyl Transferase for Peptidyl Carrier Protein Domains in Peptide Synthetases
LEN Quadri, PH Weinreb, M Lei, MM Nakano, P Zuber, CT Walsh
Biochemistry 37 (6), 1585-1595, 1998
8031998
Identification of a Mycobacterium tuberculosis gene cluster encoding the biosynthetic enzymes for assembly of the virulence-conferring siderophore mycobactin
LEN Quadri, J Sello, TA Keating, PH Weinreb, CT Walsh
Chemistry & biology 5 (11), 631-645, 1998
5471998
Partial inhibition of integrin αvβ6 prevents pulmonary fibrosis without exacerbating inflammation
GS Horan, S Wood, V Ona, DJ Li, ME Lukashev, PH Weinreb, KJ Simon, ...
American journal of respiratory and critical care medicine 177 (1), 56-65, 2008
4652008
The core Alzheimer's peptide NAC forms amyloid fibrils which seed and are seeded by β-amyloid: is NAC a common trigger or target in neurodegenerative disease?
H Han, PH Weinreb, PT Lansbury Jr
Chemistry & biology 2 (3), 163-169, 1995
4111995
The αvβ6 integrin receptor for Foot-and-mouth disease virus is expressed constitutively on the epithelial cells targeted in cattle
P Monaghan, S Gold, J Simpson, Z Zhang, PH Weinreb, SM Violette, ...
Journal of General Virology 86 (10), 2769-2780, 2005
4042005
Stromal features are predictive of disease mortality in oral cancer patients
D Marsh, K Suchak, KA Moutasim, S Vallath, C Hopper, W Jerjes, T Upile, ...
The Journal of pathology 223 (4), 470-481, 2011
3592011
Post-translational modification of polyketide and nonribosomal peptide synthases
CT Walsh, AM Gehring, PH Weinreb, LEN Quadri, RS Flugel
Current opinion in chemical biology 1 (3), 309-315, 1997
3181997
Inhibition of integrin αvβ6, an activator of latent transforming growth factor-β, prevents radiation-induced lung fibrosis
K Puthawala, N Hadjiangelis, SC Jacoby, E Bayongan, Z Zhao, Z Yang, ...
American journal of respiratory and critical care medicine 177 (1), 82-90, 2008
3072008
Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-β
JW Arndt, F Qian, BA Smith, C Quan, KP Kilambi, MW Bush, T Walz, ...
Scientific reports 8 (1), 6412, 2018
2522018
Interleukin-1β causes acute lung injury via αvβ5 and αvβ6 integrin–dependent mechanisms
MT Ganter, J Roux, B Miyazawa, M Howard, JA Frank, G Su, D Sheppard, ...
Circulation research 102 (7), 804-812, 2008
2492008
Mice that lack activity of αvβ6- and αvβ8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null mice
P Aluwihare, Z Mu, Z Zhao, D Yu, PH Weinreb, GS Horan, SM Violette, ...
Journal of cell science 122 (2), 227-232, 2009
2482009
Lysophosphatidic acid induces αvβ6 integrin-mediated TGF-β activation via the LPA2 receptor and the small G protein Gαq
MY Xu, J Porte, AJ Knox, PH Weinreb, TM Maher, SM Violette, ...
The American journal of pathology 174 (4), 1264-1279, 2009
2442009
αvβ6 integrin regulates renal fibrosis and inflammation in Alport mouse
K Hahm, ME Lukashev, Y Luo, WJ Yang, BM Dolinski, PH Weinreb, ...
The American journal of pathology 170 (1), 110-125, 2007
2342007
Constitutively activated Stat3 induces tumorigenesis and enhances cell motility of prostate epithelial cells through integrin β6
J Azare, K Leslie, H Al-Ahmadie, W Gerald, PH Weinreb, SM Violette, ...
Molecular and cellular biology 27 (12), 4444-4453, 2007
2092007
Obtustatin: A Potent Selective Inhibitor of α1β1 Integrin in Vitro and Angiogenesis in Vivo
C Marcinkiewicz, PH Weinreb, JJ Calvete, DG Kisiel, SA Mousa, ...
Cancer research 63 (9), 2020-2023, 2003
2092003
Overexpression of the αvβ6 integrin in cervical squamous cell carcinoma is a prognostic factor for decreased survival
S Hazelbag, GG Kenter, A Gorter, EJ Dreef, LA Koopman, SM Violette, ...
The Journal of Pathology: A Journal of the Pathological Society of Great …, 2007
2052007
Enhanced potency of human Sonic hedgehog by hydrophobic modification
FR Taylor, D Wen, EA Garber, AN Carmillo, DP Baker, RM Arduini, ...
Biochemistry 40 (14), 4359-4371, 2001
2022001
Fibronectin-guided migration of carcinoma collectives
S Gopal, L Veracini, D Grall, C Butori, S Schaub, S Audebert, L Camoin, ...
Nature communications 8 (1), 14105, 2017
1822017
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
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