Frank Otto Gombert
Frank Otto Gombert
GPRS Gombert Pharma Research Solutiuons, CH 4053 Basel, Switzerland
Correu electrònic verificat a - Pàgina d'inici
TítolCitada perAny
Peptidomimetic antibiotics target outer-membrane biogenesis in Pseudomonas aeruginosa
N Srinivas, P Jetter, BJ Ueberbacher, M Werneburg, K Zerbe, ...
Science 327 (5968), 1010-1013, 2010
The design, structures and therapeutic potential of protein epitope mimetics
JA Robinson, S DeMarco, F Gombert, K Moehle, D Obrecht
Drug discovery today 13 (21-22), 944-951, 2008
Discovery of novel, highly potent and selective β-hairpin mimetic CXCR4 inhibitors with excellent anti-HIV activity and pharmacokinetic profiles
SJ DeMarco, H Henze, A Lederer, K Moehle, R Mukherjee, B Romagnoli, ...
Bioorganic & medicinal chemistry 14 (24), 8396-8404, 2006
Rapid identification of phosphopeptide ligands for SH2 domains
K Müller, FO Gombert, U Manning, F Grossmüller, P Graff, H Zaegel, ...
J BioI Chern 271 (271), 16500-16505, 1996
Characterization of phosphopeptide motifs specific for the Src homology 2 domains of signal transducer and activator of transcription 1 (STAT1) and STAT3
M Wiederkehr-Adam, P Ernst, K Müller, E Bieck, FO Gombert, J Ottl, ...
Journal of Biological Chemistry 278 (18), 16117-16128, 2003
Immunological variation and immunohistochemical localization of HIV-1 Nef demonstrated with monoclonal antibodies.
V Ovod, A Lagerstedt, A Ranki, FO Gombert, R Spohn, M Tähtinen, ...
AIDS (London, England) 6 (1), 25-34, 1992
Anti-HIV activity and resistance profile of the CXC chemokine receptor 4 antagonist POL3026
G Moncunill, M Armand-Ugon, I Clotet-Codina, E Pauls, E Ballana, ...
Molecular pharmacology 73 (4), 1264-1273, 2008
Antigenic epitopes of NEF proteins from different HIV-1 strains as recognized by sera from patients with manifest and latent HIV infection
FO Gombert, W Blecha, M Tähtinen, A Ranki, S Pfeifer, W Tröger, R Braun, ...
Virology 176 (2), 458-466, 1990
Recent progress in the discovery of macrocyclic compounds as potential anti-infective therapeutics
D Obrecht, JA Robinson, F Bernardini, C Bisang, SJ DeMarco, K Moehle, ...
Current medicinal chemistry 16 (1), 42-65, 2009
Characterization of human monoclonal antibodies directed against the pp65-kD matrix antigen of human cytomegalovirus.
M Ohlin, VA Sundqvist, G Gilljam, U Rudén, FO Gombert, B Wahren, ...
Clinical and experimental immunology 84 (3), 508, 1991
Template-fixed beta-hairpin peptidomimetics with protease inhibitory activity
SJ DeMarco, K Moehle, H Henze, O Sellier, F Jung, F Gombert, D Obrecht, ...
US Patent 10,100,084, 2018
Template-fixed peptidomimetics
D Obrecht, F Gombert, SJ DeMarco, C Ludin, JW Vrijbloed, K Moehle, ...
US Patent 10,144,765, 2018
Template-fixed beta-hairpin peptidomimetics with CXCR4 antagonizing activity
J Zumbrunn, SJ Demarco, R Mukherjee, K Moehle, JA Robinson, ...
Synthetic peptide segments from the Escherichia coli porin OmpF constitute leukocyte activators.
HM Vordermeier, P Hoffmann, FO Gombert, G Jung, WG Bessler
Infection and immunity 58 (8), 2719-2724, 1990
Template-fixed beta-hairpin peptidomimetics with protease inhibitory activity
SJ DeMarco, K Moehle, H Henze, O Sellier, F Jung, F Gombert, D Obrecht, ...
US Patent 8,658,604, 2014
Alanine and D-amino acid scan of human parathyroid hormone
FO Gombert, R Gamse, JHM Feyen, F Cardinaux
Template-fixed peptidomimetics with CXCR7 modulating activity
FO Gombert, A Lederer, D Obrecht, B Romagnoli, C Bisang, C Ludin
US Patent 8,629,112, 2014
W Bauer, R Breckenridge, F Cardinaux, F Gombert, H Gram, P Ramage, ...
US Patent App. 10/848,279, 2005
Expression kinetics and cellular localization of HIV Tat and Nef proteins in relation to the expression of viral structural mRNA and viral particles
KJE Krohn, V Ovod, A Langerstedt, U Saarialho-Kere, A Ranki, ...
Vaccines 91, 97-101, 1991
Beta-hairpin peptidomimetics having CXCR4 antagonizing activity
D Obrecht, F Gombert, A Lederer, B Romagnoli, C Bisang
US Patent 8,865,656, 2014
En aquests moments el sistema no pot dur a terme l'operació. Torneu-ho a provar més tard.
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