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Daniel Botelho Costa
Daniel Botelho Costa
Professor of Medicine | Harvard Medical School | Beth Israel Deaconess Medical Center
Dirección de correo verificada de bidmc.harvard.edu - Página principal
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Anaplastic lymphoma kinase inhibition in non–small-cell lung cancer
EL Kwak, YJ Bang, DR Camidge, AT Shaw, B Solomon, RG Maki, SHI Ou, ...
New England Journal of Medicine 363 (18), 1693-1703, 2010
55042010
Clinical Features and Outcome of Patients With Non–Small-Cell Lung Cancer Who Harbor EML4-ALK
AT Shaw, BY Yeap, M Mino-Kenudson, SR Digumarthy, DB Costa, ...
Journal of clinical oncology 27 (26), 4247-4253, 2009
24692009
Crizotinib in ROS1-Rearranged Non–Small-Cell Lung Cancer
AT Shaw, SHI Ou, YJ Bang, DR Camidge, BJ Solomon, R Salgia, GJ Riely, ...
New England Journal of Medicine 371 (21), 1963-1971, 2014
22242014
Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: updated results from a phase 1 study
DR Camidge, YJ Bang, EL Kwak, AJ Iafrate, M Varella-Garcia, SB Fox, ...
The lancet oncology 13 (10), 1011-1019, 2012
15602012
Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints
S Koyama, EA Akbay, YY Li, GS Herter-Sprie, KA Buczkowski, ...
Nature communications 7 (1), 10501, 2016
15102016
Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis
AT Shaw, BY Yeap, BJ Solomon, GJ Riely, J Gainor, JA Engelman, ...
The lancet oncology 12 (11), 1004-1012, 2011
11512011
Clinical Experience With Crizotinib in Patients With Advanced ALK-Rearranged Non–Small-Cell Lung Cancer and Brain Metastases
DB Costa, AT Shaw, SHI Ou, BJ Solomon, GJ Riely, MJ Ahn, C Zhou, ...
Journal of Clinical Oncology 33 (17), 1881-1888, 2015
6892015
Assessment of resistance mechanisms and clinical implications in patients with EGFR T790M–positive lung cancer and acquired resistance to osimertinib
GR Oxnard, Y Hu, KF Mileham, H Husain, DB Costa, P Tracy, N Feeney, ...
JAMA oncology 4 (11), 1527-1534, 2018
6742018
CSF concentration of the anaplastic lymphoma kinase inhibitor crizotinib
DB Costa, S Kobayashi, SS Pandya, WL Yeo, Z Shen, W Tan, KD Wilner
Journal of Clinical Oncology 29 (15), e443-e445, 2011
6682011
EGFR exon 20 insertion mutations in non-small-cell lung cancer: preclinical data and clinical implications
H Yasuda, S Kobayashi, DB Costa
The lancet oncology 13 (1), e23-e31, 2012
6382012
RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer
MJ Niederst, LV Sequist, JT Poirier, CH Mermel, EL Lockerman, ...
Nature communications 6 (1), 6377, 2015
6122015
Structural, biochemical, and clinical characterization of epidermal growth factor receptor (EGFR) exon 20 insertion mutations in lung cancer
H Yasuda, E Park, CH Yun, NJ Sng, AR Lucena-Araujo, WL Yeo, ...
Science translational medicine 5 (216), 216ra177-216ra177, 2013
5912013
BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations
DB Costa, B Halmos, A Kumar, ST Schumer, MS Huberman, TJ Boggon, ...
PLoS medicine 4 (10), e315, 2007
5822007
Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non–small-cell lung cancers dependent on the epidermal growth factor receptor pathway
KSH Nguyen, S Kobayashi, DB Costa
Clinical lung cancer 10 (4), 281-289, 2009
5772009
A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response
Z Chen, K Cheng, Z Walton, Y Wang, H Ebi, T Shimamura, Y Liu, ...
Nature 483 (7391), 613-617, 2012
5042012
Brain metastases in patients with EGFR-mutated or ALK-rearranged non-small-cell lung cancers
D Rangachari, N Yamaguchi, PA VanderLaan, E Folch, A Mahadevan, ...
Lung cancer 88 (1), 108-111, 2015
4972015
Randomized phase II study of erlotinib plus tivantinib versus erlotinib plus placebo in previously treated non–small-cell lung cancer
LV Sequist, J Von Pawel, EG Garmey, WL Akerley, W Brugger, D Ferrari, ...
Journal of Clinical Oncology 29 (24), 3307-3315, 2011
4682011
Development of Central Nervous System Metastases in Patients with Advanced Non–Small Cell Lung Cancer and Somatic EGFR Mutations Treated with Gefitinib …
S Heon, BY Yeap, GJ Britt, DB Costa, MS Rabin, DM Jackman, ...
Clinical cancer research 16 (23), 5873-5882, 2010
2722010
Intracranial Efficacy of Crizotinib Versus Chemotherapy in Patients With Advanced ALK-Positive Non–Small-Cell Lung Cancer: Results From PROFILE 1014
BJ Solomon, F Cappuzzo, E Felip, FH Blackhall, DB Costa, DW Kim, ...
Journal of Clinical Oncology 34 (24), 2858-2865, 2016
2672016
Durable clinical response to entrectinib in NTRK1-rearranged non-small cell lung cancer
AF Farago, LP Le, Z Zheng, A Muzikansky, A Drilon, M Patel, TM Bauer, ...
Journal of Thoracic Oncology 10 (12), 1670-1674, 2015
2332015
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