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Consuelo Gajate
Consuelo Gajate
Científica, CIB, Consejo Superior de Investigaciones Científicas, Madrid, Spain
Verified email at cib.csic.es
Title
Cited by
Cited by
Year
Microtubules, microtubule-interfering agents and apoptosis
F Mollinedo, C Gajate
Apoptosis 8 (5), 413-450, 2003
6412003
Lipid rafts as major platforms for signaling regulation in cancer
F Mollinedo, C Gajate
Advances in biological regulation 57, 130-146, 2015
3242015
The antitumor ether lipid ET-18-OCH3 induces apoptosis through translocation and capping of Fas/CD95 into membrane rafts in human leukemic cells
C Gajate, F Mollinedo
Blood, The Journal of the American Society of Hematology 98 (13), 3860-3863, 2001
3222001
Edelfosine and perifosine induce selective apoptosis in multiple myeloma by recruitment of death receptors and downstream signaling molecules into lipid rafts
C Gajate, F Mollinedo
Blood 109 (2), 711-719, 2007
3012007
Selective Induction of Apoptosis in Cancer Cells by the Ether Lipid ET-18-OCH3 (Edelfosine): Molecular Structure Requirements, Cellular Uptake, and Protection by Bcl-2 and …
F Mollinedo, JL Fernández-Luna, C Gajate, B Martín-Martín, A Benito, ...
Cancer research 57 (7), 1320-1328, 1997
2821997
Intracellular triggering of Fas aggregation and recruitment of apoptotic molecules into Fas-enriched rafts in selective tumor cell apoptosis
C Gajate, E del Canto-Jañez, AU Acuña, F Amat-Guerri, E Geijo, ...
The Journal of experimental medicine 200 (3), 353-365, 2004
2502004
Cytoskeleton-mediated death receptor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy
C Gajate, F Mollinedo
Journal of Biological Chemistry 280 (12), 11641-11647, 2005
2292005
Biological activities, mechanisms of action and biomedical prospect of the antitumor ether phospholipid ET-18-OCH3 (edelfosine), a proapoptotic agent in tumor cells
C Gajate, F Mollinedo
Current drug metabolism 3 (5), 491-525, 2002
2202002
Fas/CD95 death receptor and lipid rafts: new targets for apoptosis-directed cancer therapy
F Mollinedo, C Gajate
Drug resistance updates 9 (1-2), 51-73, 2006
1962006
Selective induction of apoptosis by capsaicin in transformed cells: the role of reactive oxygen species and calcium
A Macho, MA Calzado, J Muñoz-Blanco, C Gómez-Díaz, C Gajate, ...
Cell Death & Differentiation 6 (2), 155-165, 1999
1761999
Intracellular triggering of Fas, independently of FasL, as a new mechanism of antitumor ether lipid‐induced apoptosis
C Gajate, RI Fonteriz, C Cabaner, G Alvarez‐Noves, Y Alvarez‐Rodriguez, ...
International journal of cancer 85 (5), 674-682, 2000
1732000
Lipid rafts as signaling hubs in cancer cell survival/death and invasion: implications in tumor progression and therapy: thematic review series: biology of lipid rafts
F Mollinedo, C Gajate
Journal of lipid research 61 (5), 611-635, 2020
1692020
Major co-localization of the extracellular-matrix degradative enzymes heparanase and gelatinase in tertiary granules of human neutrophils
F MOLLINEDO, M NAKAJIMA, A LLORENS, E BARBOSA, S CALLEJO, ...
Biochemical Journal 327 (3), 917-923, 1997
1661997
ET-18-OCH3 (edelfosine): a selective antitumour lipid targeting apoptosis through intracellular activation of Fas/CD95 death receptor
F Mollinedo, C Gajate, S Martín-Santamaría, F Gago
Current medicinal chemistry 11 (24), 3163-3184, 2004
1632004
Combinatorial SNARE complexes modulate the secretion of cytoplasmic granules in human neutrophils
F Mollinedo, J Calafat, H Janssen, B Martín-Martín, J Canchado, ...
The Journal of Immunology 177 (5), 2831-2841, 2006
1452006
Involvement of mitochondria and caspase‐3 in ET‐18‐OCH3‐induced apoptosis of human leukemic cells
C Gajate, AM Santos‐Beneit, A Macho, MC Lazaro, ...
International journal of cancer 86 (2), 208-218, 2000
1442000
Lipid raft-targeted therapy in multiple myeloma
F Mollinedo, J De la Iglesia-Vicente, C Gajate, ...
Oncogene 29 (26), 3748-3757, 2010
1392010
Involvement of raft aggregates enriched in Fas/CD95 death-inducing signaling complex in the antileukemic action of edelfosine in Jurkat cells
C Gajate, F Gonzalez-Camacho, F Mollinedo
PLoS One 4 (4), e5044, 2009
1362009
Further naphthylcombretastatins. An investigation on the role of the naphthalene moiety
ABS Maya, C Pérez-Melero, C Mateo, D Alonso, JL Fernández, C Gajate, ...
Journal of medicinal chemistry 48 (2), 556-568, 2005
1362005
In vitro and In vivo Selective Antitumor Activity of Edelfosine against Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia Involving Lipid Rafts
F Mollinedo, J de la Iglesia-Vicente, C Gajate, AEH de Mendoza, ...
Clinical Cancer Research 16 (7), 2046-2054, 2010
1222010
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