| Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis TRM Lannagan, YK Lee, T Wang, J Roper, ML Bettington, L Fennell, ... Gut 68 (4), 684-692, 2019 | 105 | 2019 |
| Oncogenic BRAF mutation induces DNA methylation changes in a murine model for human serrated colorectal neoplasia CE Bond, C Liu, F Kawamata, DM McKeone, W Fernando, S Jamieson, ... Epigenetics 13 (1), 40-48, 2018 | 66 | 2018 |
| The role of APC in WNT pathway activation in serrated neoplasia J Borowsky, T Dumenil, M Bettington, SA Pearson, C Bond, L Fennell, ... Modern pathology 31 (3), 495-504, 2018 | 61 | 2018 |
| Integrative genome-scale DNA methylation analysis of a large and unselected cohort reveals 5 distinct subtypes of colorectal adenocarcinomas L Fennell, T Dumenil, L Wockner, G Hartel, K Nones, C Bond, J Borowsky, ... Cellular and molecular gastroenterology and hepatology 8 (2), 269-290, 2019 | 52 | 2019 |
| APC Mutation Marks an Aggressive Subtype of BRAF Mutant Colorectal Cancers LJ Fennell, A Kane, C Liu, D McKeone, W Fernando, C Su, C Bond, ... Cancers 12 (5), 1171, 2020 | 33 | 2020 |
| DNA methylation changes that precede onset of dysplasia in advanced sessile serrated adenomas C Liu, LJ Fennell, ML Bettington, NI Walker, J Dwine, BA Leggett, ... Clinical Epigenetics 11, 1-13, 2019 | 26 | 2019 |
| MLH1–93 G/a polymorphism is associated with MLH1 promoter methylation and protein loss in dysplastic sessile serrated adenomas with BRAFV600E mutation LJ Fennell, S Jamieson, D McKeone, T Corish, M Rohdmann, T Furner, ... BMC cancer 18, 1-7, 2018 | 21 | 2018 |
| Copy number profiles of paired primary and metastatic colorectal cancers F Kawamata, AM Patch, K Nones, C Bond, D McKeone, SA Pearson, ... Oncotarget 9 (3), 3394, 2018 | 18 | 2018 |
| Alterations in signaling pathways that accompany spontaneous transition to malignancy in a mouse model of BRAF mutant microsatellite stable colorectal cancer AM Kane, LJ Fennell, C Liu, J Borowsky, DM McKeone, CE Bond, ... Neoplasia 22 (2), 120-128, 2020 | 17 | 2020 |
| RNF43 is mutated less frequently in Lynch Syndrome compared with sporadic microsatellite unstable colorectal cancers LJ Fennell, M Clendenning, DM McKeone, SH Jamieson, S Balachandran, ... Familial cancer 17, 63-69, 2018 | 17 | 2018 |
| Braf mutation induces rapid neoplastic transformation in the aged and aberrantly methylated intestinal epithelium L Fennell, A Kane, C Liu, D McKeone, C Su, G Hartel, C Bond, ... Gut, 2021 | 12 | 2021 |
| Epithelial de-differentiation triggered by co-ordinate epigenetic inactivation of the EHF and CDX1 transcription factors drives colorectal cancer progression IY Luk, LJ Jenkins, KL Schoffer, I Ng, JWT Tse, D Mouradov, ... Cell Death & Differentiation 29 (11), 2288-2302, 2022 | 8 | 2022 |
| Aspirin reduces the incidence of metastasis in a pre-clinical study of Braf mutant serrated colorectal neoplasia AM Kane, C Liu, LJ Fennell, DM McKeone, CE Bond, PM Pollock, ... British Journal of Cancer 124 (11), 1820-1827, 2021 | 4 | 2021 |
| Comparative analysis of Illumina Mouse Methylation BeadChip and reduced-representation bisulfite sequencing for routine DNA methylation analysis LJ Fennell, G Hartel, DM McKeone, CE Bond, A Kane, BA Leggett, ... Cell Reports Methods 2 (11), 2022 | 3 | 2022 |
| Global methylome scores correlate with histological subtypes of colorectal carcinoma and show different associations with common clinical and molecular features MC Turpín-Sevilla, F Pérez-Sanz, J García-Solano, P Sebastián-León, ... Cancers 13 (20), 5165, 2021 | 1 | 2021 |
| Oncogenic BRAF mutation induces widespread DNA hypermethylation in a murine model for human serrated colorectal neoplasia V Whitehall, C Bond, C Liu, F Kawamata, D McKeone, S Jamieson, ... Cancer Research 77 (13_Supplement), 5375-5375, 2017 | 1 | 2017 |
| KRAS mutant bowel cancers segregate into two distinct subgroups J Borowsky, C Su, L Fennell, M Burge, J Liu, AD Costa, S Ogino, ... Journal of Gastroenterology and Hepatology 38, 28-29, 2023 | | 2023 |
| Determining if osteopontin is an immune checkpoint of KRAS mutant colorectal cancer B Nowlan, J Borowsky, T Dumenil, S Tria, J Wright, L Fennell, C Bond, ... Journal of Gastroenterology and Hepatology 38, 24-24, 2023 | | 2023 |
| Attenuation of the CpG Island Methylator Phenotype and lack of WNT signaling activation restrains Kras mutant intestinal neoplasia LJ Fennell, S Tria, C Liu, A Kane, D McKeone, J Borowsky, L Chai, ... bioRxiv, 2023.12. 21.572936, 2023 | | 2023 |
| Aspirin Synergizes with Regorafenib to Reduce Growth of Colorectal Cancer C Su, LJ Fennell, CE Bond, AM Kane, G Kerr, T Jardé, D Micati, RM Engel, ... bioRxiv, 2022.02. 11.480021, 2022 | | 2022 |
