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Binghui Shen
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Replication fork stability confers chemoresistance in BRCA-deficient cells
A Ray Chaudhuri, E Callen, X Ding, E Gogola, AA Duarte, JE Lee, ...
Nature 535 (7612), 382-387, 2016
8182016
Structural basis for FEN-1 substrate specificity and PCNA-mediated activation in DNA replication and repair
BR Chapados, DJ Hosfield, S Han, J Qiu, B Yelent, B Shen, JA Tainer
Cell 116 (1), 39-50, 2004
3402004
Human flap endonuclease structures, DNA double-base flipping, and a unified understanding of the FEN1 superfamily
SE Tsutakawa, S Classen, BR Chapados, AS Arvai, LD Finger, ...
Cell 145 (2), 198-211, 2011
3182011
Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity
DJ Hosfield, CD Mol, B Shen, JA Tainer
Cell 95 (1), 135-146, 1998
3121998
Fen1 mutations result in autoimmunity, chronic inflammation and cancers
L Zheng, H Dai, M Zhou, M Li, P Singh, J Qiu, W Tsark, Q Huang, ...
Nature medicine 13 (7), 812-819, 2007
2732007
Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates
L Zheng, M Zhou, Z Guo, H Lu, L Qian, H Dai, J Qiu, E Yakubovskaya, ...
Molecular cell 32 (3), 325-336, 2008
2682008
Removal of oxidative DNA damage via FEN1-dependent long-patch base excision repair in human cell mitochondria
P Liu, L Qian, JS Sung, NC de Souza-Pinto, L Zheng, DF Bogenhagen, ...
Molecular and cellular biology 28 (16), 4975-4987, 2008
2592008
PprI: a general switch responsible for extreme radioresistance of Deinococcus radiodurans
Y Hua, I Narumi, G Gao, B Tian, K Satoh, S Kitayama, B Shen
Biochemical and biophysical research communications 306 (2), 354-360, 2003
2422003
O-GlcNAcylation of G6PD promotes the pentose phosphate pathway and tumor growth
X Rao, X Duan, W Mao, X Li, Z Li, Q Li, Z Zheng, H Xu, M Chen, PG Wang, ...
Nature communications 6 (1), 8468, 2015
2272015
Functional regulation of FEN1 nuclease and its link to cancer
L Zheng, J Jia, LD Finger, Z Guo, C Zer, B Shen
Nucleic acids research 39 (3), 781-794, 2011
2222011
Okazaki fragment maturation: nucleases take centre stage
L Zheng, B Shen
Journal of molecular cell biology 3 (1), 23-30, 2011
2032011
Saccharomyces cerevisiae RNase H(35) Functions in RNA Primer Removal during Lagging-Strand DNA Synthesis, Most Efficiently in Cooperation with Rad27 …
J Qiu, Y Qian, P Frank, U Wintersberger, B Shen
Molecular and cellular biology 19 (12), 8361-8371, 1999
1881999
Novel function of the flap endonuclease 1 complex in processing stalled DNA replication forks
L Zheng, M Zhou, Q Chai, J Parrish, D Xue, SM Patrick, JJ Turchi, ...
EMBO reports 6 (1), 83-89, 2005
1832005
Mammalian DNA2 helicase/nuclease cleaves G‐quadruplex DNA and is required for telomere integrity
W Lin, S Sampathi, H Dai, C Liu, M Zhou, J Hu, Q Huang, J Campbell, ...
The EMBO journal 32 (10), 1425-1439, 2013
1772013
Multiple but dissectible functions of FEN‐1 nucleases in nucleic acid processing, genome stability and diseases
B Shen, P Singh, R Liu, J Qiu, L Zheng, LD Finger, S Alas
Bioessays 27 (7), 717-729, 2005
1762005
Reciprocal regulation of Akt and Oct4 promotes the self-renewal and survival of embryonal carcinoma cells
Y Lin, Y Yang, W Li, Q Chen, J Li, X Pan, L Zhou, C Liu, C Chen, J He, ...
Molecular cell 48 (4), 627-640, 2012
1752012
Overexpression and Hypomethylation of Flap Endonuclease 1 Gene in Breast and Other Cancers
P Singh, M Yang, H Dai, D Yu, Q Huang, W Tan, KH Kernstine, D Lin, ...
Molecular Cancer Research 6 (11), 1710-1717, 2008
1602008
Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding
Z Guo, L Zheng, H Xu, H Dai, M Zhou, MR Pascua, QM Chen, B Shen
Nature chemical biology 6 (10), 766-773, 2010
1522010
CtIP maintains stability at common fragile sites and inverted repeats by end resection-independent endonuclease activity
H Wang, Y Li, LN Truong, LZ Shi, PYH Hwang, J He, J Do, MJ Cho, H Li, ...
Molecular cell 54 (6), 1012-1021, 2014
1482014
Mutations in DNA2 link progressive myopathy to mitochondrial DNA instability
D Ronchi, A Di Fonzo, W Lin, A Bordoni, C Liu, E Fassone, S Pagliarani, ...
The American Journal of Human Genetics 92 (2), 293-300, 2013
1482013
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