| Hydroarylation of arenes via reductive radical-polar crossover AR Flynn, KA McDaniel, ME Hughes, DB Vogt, NT Jui Journal of the American Chemical Society 142 (20), 9163-9168, 2020 | 85 | 2020 |
| Development of the first low nanomolar Liver Receptor Homolog-1 agonist through structure-guided design SG Mays, AR Flynn, JL Cornelison, CD Okafor, H Wang, G Wang, ... Journal of Medicinal Chemistry 62 (24), 11022-11034, 2019 | 27 | 2019 |
| Crystal structures of the nuclear receptor, liver receptor homolog 1, bound to synthetic agonists SG Mays, CD Okafor, RJ Whitby, D Goswami, J Stec, AR Flynn, ... Journal of Biological Chemistry 291 (49), 25281-25291, 2016 | 27 | 2016 |
| Development of Hybrid Phospholipid Mimics as Effective Agonists for Liver Receptor Homologue-1 AR Flynn, SG Mays, EA Ortlund, NT Jui ACS medicinal chemistry letters 9 (10), 1051-1056, 2018 | 22 | 2018 |
| Development of a Versatile and Sensitive Direct Ligand Binding Assay for Human NR5A Nuclear Receptors EH D’Agostino, AR Flynn, JL Cornelison, SG Mays, A Patel, NT Jui, ... ACS Medicinal Chemistry Letters 11 (3), 365-370, 2019 | 12 | 2019 |
| A phospholipid mimetic targeting LRH-1 ameliorates colitis SG Mays, EH D’Agostino, AR Flynn, X Huang, G Wang, X Liu, EJ Millings, ... Cell Chemical Biology, 2022 | 8 | 2022 |
| Workflow for Biocatalytic Reaction Performance Prediction and Analysis H Clements, A Flynn, B Nicholls, D Grosheva, T Hyster, M Sigman | 2 | 2021 |
| Modulators of liver receptor homologue 1 (LRH-1) and uses E Ortlund, S Mays, N Jui, A Flynn, M Dugan US Patent 10,843,996, 2020 | 1 | 2020 |
| A novel phospholipid mimetic targeting LRH-1 ameliorates colitis SG Mays, EH D’Agostino, AR Flynn, X Huang, G Wang, X Liu, EJ Millings, ... | 1 | 2020 |
| Tapping into a phospholipid-LRH-1 axis yields a powerful anti-inflammatory agent with in vivo activity against colitis SG Mays, EH D'Agostino, AR Flynn, X Huang, G Wang, X Liu, EJ Millings, ... bioRxiv, 2020 | 1 | 2020 |
| Arene Dearomatization via Radical Hydroarylation A Flynn, K McDaniel, M Hughes, D Vogt, N Jui ChemRxiv, 2019 | 1 | 2019 |
| Structural and Data Science-Driven Analysis to Assess Substrate Specificity of Diketopiperazine Reverse Prenyltransferase NotF: Cascade Biocatalytic Synthesis of (–)-Eurotiumin A SP Kelly, VV Shende, AR Flynn, Q Dan, Y Ye, JL Smith, S Tsukamoto, ... | | 2021 |
| Modulators of Liver Receptor Homologue 1 (LRH-1) and Uses E Ortlund, S Mays, N Jui, A Flynn, M Dugan US Patent App. 17/071,382, 2021 | | 2021 |
| Development of picomolar liver receptor homolog‐1 agonist ML Cato, J Cornelison, A Flynn, E D’Agostino, N Jui, E Ortlund The FASEB Journal 34 (S1), 1-1, 2020 | | 2020 |
| Structure, Synthesis, and Reactivity: Intentional Design Approaches to Agonists for Liver Receptor Homolog-1 and Photochemical Arene Dearomatization AR Flynn | | 2020 |
| Synthesis and mechanistic investigation of phospholipid-mimicking small molecules as synthetic modulators for liver receptor homologue-1 A Flynn, N Jui ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |
| Development of a Robust Direct Binding Assay for Phospholipid‐Sensing NR5A Nuclear Receptors EH D'Agostino, J Cornelison, S Mays, A Flynn, N Jui, E Ortlund The FASEB Journal 33 (S1), 634.3-634.3, 2019 | | 2019 |
| Crystal Structures of the Nuclear Receptor, Liver Receptor Homolog 1, Bound to Synthetic Agonists Reveal a Novel Mechanism of Activation D Okafor, SG Mays, RJ Whitby, D Goswami, J Stec, AR Flynn, MC Dugan, ... The FASEB Journal 31, 923.4-923.4, 2017 | | 2017 |
| Targeting the Nuclear Receptor LRH-1 with Synthetic Agonists SG Mays, CD Okafor, R Whitby, D Goswami, J Stec, A Flynn, M Dugan, ... ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 73, A98-A98, 2017 | | 2017 |
| Suzanne G. Mays1, C. Denise Okafor1, Richard J. Whitby3, Devrishi Goswami4, Józef Stec3, Autumn R. Flynn2, Michael C. Dugan2, Nathan T. Jui2, Patrick R. Griffin4, and Eric A … AR Flynn, MC Dugan, NT Jui, PR Griffin, EA Ortlund | | 2016 |
