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Xiakun Chu
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Multiscaled exploration of coupled folding and binding of an intrinsically disordered molecular recognition element in measles virus nucleoprotein
Y Wang, X Chu, S Longhi, P Roche, W Han, E Wang, J Wang
Proceedings of the National Academy of Sciences 110 (40), E3743-E3752, 2013
1132013
Importance of electrostatic interactions in the association of intrinsically disordered histone chaperone Chz1 and histone H2A. Z-H2B
X Chu, Y Wang, L Gan, Y Bai, W Han, E Wang, J Wang
PLoS computational biology 8 (7), e1002608, 2012
892012
Multi-scaled explorations of binding-induced folding of intrinsically disordered protein inhibitor IA3 to its target enzyme
J Wang, Y Wang, X Chu, SJ Hagen, W Han, E Wang
PLoS computational biology 7 (4), e1001118, 2011
832011
Topography of funneled landscapes determines the thermodynamics and kinetics of protein folding
J Wang, RJ Oliveira, X Chu, PC Whitford, J Chahine, W Han, E Wang, ...
Proceedings of the National Academy of Sciences 109 (39), 15763-15768, 2012
672012
Quantifying the topography of the intrinsic energy landscape of flexible biomolecular recognition
X Chu, L Gan, E Wang, J Wang
Proceedings of the National Academy of Sciences 110 (26), E2342-E2351, 2013
662013
Dynamic conformational change regulates the protein-DNA recognition: an investigation on binding of a Y-family polymerase to its target DNA
X Chu, F Liu, BA Maxwell, Y Wang, Z Suo, H Wang, W Han, J Wang
PLoS computational biology 10 (9), e1003804, 2014
562014
Molecular mechanism of multispecific recognition of Calmodulin through conformational changes
F Liu, X Chu, HP Lu, J Wang
Proceedings of the National Academy of Sciences 114 (20), E3927-E3934, 2017
462017
Multidomain protein solves the folding problem by multifunnel combined landscape: Theoretical investigation of a Y-family DNA polymerase
Y Wang, X Chu, Z Suo, E Wang, J Wang
Journal of the American Chemical Society 134 (33), 13755-13764, 2012
422012
Specificity and affinity quantification of flexible recognition from underlying energy landscape topography
X Chu, J Wang
PLoS computational biology 10 (8), e1003782, 2014
352014
Roles of conformational disorder and downhill folding in modulating protein–DNA recognition
X Chu, V Muņoz
Physical Chemistry Chemical Physics 19, 28527-28539, 2017
242017
Binding mechanism and dynamic conformational change of C subunit of PKA with different pathways
WT Chu, X Chu, J Wang
Proceedings of the National Academy of Sciences 114 (38), E7959-E7968, 2017
222017
Conformational state switching and pathways of chromosome dynamics in cell cycle
X Chu, J Wang
Applied Physics Reviews 7 (3), 2020
192020
Microscopic Chromosomal Structural and Dynamical Origin of Cell Differentiation and Reprogramming
X Chu, J Wang
Advanced Science 7 (20), 2001572, 2020
182020
Investigations of the underlying mechanisms of HIF-1α and CITED2 binding to TAZ1
WT Chu, X Chu, J Wang
Proceedings of the National Academy of Sciences 117 (11), 5595-5603, 2020
162020
Position-, disorder-, and salt-dependent diffusion in binding-coupled-folding of intrinsically disordered proteins
X Chu, J Wang
Physical Chemistry Chemical Physics 21 (10), 5634-5645, 2019
162019
Confinement and Crowding Effects on Folding of a Multidomain Y-Family DNA Polymerase
X Chu, Z Suo, J Wang
Journal of Chemical Theory and Computation 16 (2), 1319-1332, 2020
152020
Deciphering the molecular mechanism of the cancer formation by chromosome structural dynamics
X Chu, J Wang
PLoS computational biology 17 (11), e1009596, 2021
112021
Uncovering the underlying physical mechanisms of biological systems via quantification of landscape and flux
L Xu, X Chu, Z Yan, X Zheng, K Zhang, F Zhang, H Yan, W Wu, J Wang
Chinese Physics B 25 (1), 016401, 2015
102015
Investigating the trade-off between folding and function in a multidomain Y-family DNA polymerase
X Chu, Z Suo, J Wang
eLife 9, e60434, 2020
82020
Quantifying Chromosome Structural Reorganizations During Differentiation, Reprogramming, and Transdifferentiation
X Chu, J Wang
Physical Review Letters 129 (6), 068102, 2022
72022
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Articles 1–20