Modeling atrial fibrillation using human embryonic stem cell-derived atrial tissue Z Laksman, M Wauchop, E Lin, S Protze, J Lee, W Yang, F Izaddoustdar, ... Scientific reports 7 (1), 5268, 2017 | 86 | 2017 |
The zebrafish heart as a model of mammalian cardiac function CE Genge, E Lin, L Lee, XY Sheng, K Rayani, M Gunawan, CM Stevens, ... Reviews of Physiology, Biochemistry and Pharmacology, Vol. 171, 99-136, 2016 | 78 | 2016 |
Ibrutinib displays atrial-specific toxicity in human stem cell-derived cardiomyocytes S Shafaattalab, E Lin, E Christidi, H Huang, Y Nartiss, A Garcia, J Lee, ... Stem Cell Reports 12 (5), 996-1006, 2019 | 56 | 2019 |
Variation in RARG increases susceptibility to doxorubicin-induced cardiotoxicity in patient specific induced pluripotent stem cell-derived cardiomyocytes E Christidi, H Huang, S Shafaattalab, A Maillet, E Lin, K Huang, ... Scientific reports 10 (1), 10363, 2020 | 42 | 2020 |
Investigating the genetic causes of sudden unexpected death in children through targeted next-generation sequencing analysis LJ Dewar, M Alcaide, D Fornika, L D’Amato, S Shafaatalab, CM Stevens, ... Circulation: Cardiovascular Genetics 10 (4), e001738, 2017 | 39 | 2017 |
A carcinoembryonic antigen-specific cell therapy selectively targets tumor cells with HLA loss of heterozygosity in vitro and in vivo ML Sandberg, X Wang, AD Martin, DP Nampe, GB Gabrelow, CZ Li, ... Science Translational Medicine 14 (634), eabm0306, 2022 | 31 | 2022 |
Drug screening platform using human induced pluripotent stem cell-derived atrial cardiomyocytes and optical mapping MG Gunawan, SS Sangha, S Shafaattalab, E Lin, DA Heims-Waldron, ... Stem cells translational medicine 10 (1), 68-82, 2021 | 31 | 2021 |
Zebrafish as a model of mammalian cardiac function: optically mapping the interplay of temperature and rate on voltage and calcium dynamics K Rayani, E Lin, C Craig, M Lamothe, S Shafaattalab, M Gunawan, AY Li, ... Progress in biophysics and molecular biology 138, 69-90, 2018 | 23 | 2018 |
The hERG channel activator, RPR260243, enhances protective IKr current early in the refractory period reducing arrhythmogenicity in zebrafish hearts YP Shi, ZK Pang, R Venkateshappa, M Gunawan, J Kemp, E Truong, ... American Journal of Physiology-Heart and Circulatory Physiology 319 (2 …, 2020 | 22 | 2020 |
In vitro analyses of suspected arrhythmogenic thin filament variants as a cause of sudden cardiac death in infants S Shafaattalab, AY Li, E Lin, CM Stevens, LJ Dewar, FC Lynn, S Sanatani, ... Proceedings of the National Academy of Sciences 116 (14), 6969-6974, 2019 | 21 | 2019 |
Mechanisms of arrhythmogenicity of hypertrophic cardiomyopathy-associated troponin T (TNNT2) variant I79N S Shafaattalab, AY Li, MG Gunawan, BR Kim, F Jayousi, Y Maaref, ... Frontiers in cell and developmental biology 9, 787581, 2021 | 17 | 2021 |
Physiological phenotyping of the adult zebrafish heart E Lin, S Shafaattalab, J Gill, B Al-Zeer, C Craig, M Lamothe, K Rayani, ... Marine genomics 49, 100701, 2020 | 14 | 2020 |
Investigating the utility of adult zebrafish ex vivo whole hearts to pharmacologically screen hERG channel activator compounds CM Hull, CE Genge, Y Hobbs, K Rayani, E Lin, M Gunawan, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2019 | 14 | 2019 |
Atrial-specific hiPSC-derived cardiomyocytes in drug discovery and disease modeling M Gharanei, S Shafaattalab, S Sangha, M Gunawan, Z Laksman, ... Methods 203, 364-377, 2022 | 12 | 2022 |
RARG S427L attenuates the DNA repair response to doxorubicin in induced pluripotent stem cell-derived cardiomyocytes H Huang, E Christidi, S Shafaattalab, MK Davis, GF Tibbits, LR Brunham Stem Cell Reports 17 (4), 756-765, 2022 | 12 | 2022 |
Investigating inherited arrhythmias using hiPSC-derived cardiomyocytes A Arslanova, S Shafaattalab, E Lin, T Barszczewski, L Hove-Madsen, ... Methods 203, 542-557, 2022 | 9 | 2022 |
Using hiPSC‐CMs to Examine Mechanisms of Catecholaminergic Polymorphic Ventricular Tachycardia A Arslanova, S Shafaattalab, K Ye, P Asghari, L Lin, BR Kim, TM Roston, ... Current Protocols 1 (12), e320, 2021 | 6 | 2021 |
229 A2B530, an autologous CEA-directed Tmod T-cell therapy with an inhibitory receptor gated by HLA-A* 02 to target colorectal, pancreatic, and lung cancer JR Hecht, M Sandberg, X Wang, A Martin, D Nampe, G Gabrelow, C Li, ... Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022 | 4 | 2022 |
Targeted activation of human ether-à-go-go-related gene channels rescues electrical instability induced by the R56Q+/− long QT syndrome variant R Venkateshappa, DV Hunter, P Muralidharan, RS Nagalingam, G Huen, ... Cardiovascular Research 119 (15), 2522-2535, 2023 | 2 | 2023 |
A perspective on Notch signalling in progression and arrhythmogenesis in familial hypertrophic and dilated cardiomyopathies P Langa, S Shafaattalab, PH Goldspink, BM Wolska, AA Fernandes, ... Philosophical Transactions of the Royal Society B 378 (1879), 20220176, 2023 | 2 | 2023 |