Hunain Alam
Hunain Alam
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Novel function of keratins 5 and 14 in proliferation and differentiation of stratified epithelial cells
H Alam, L Sehgal, ST Kundu, SN Dalal, MM Vaidya
Molecular biology of the cell 22 (21), 4068-4078, 2011
2112011
KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling
KW Wagner, H Alam, SS Dhar, U Giri, N Li, Y Wei, D Giri, T Cascone, ...
The Journal of clinical investigation 123 (12), 5231-5246, 2013
1282013
Histone methylation modifiers in cellular signaling pathways
H Alam, B Gu, MG Lee
Cellular and molecular life sciences 72 (23), 4577-4592, 2015
742015
Fascin overexpression promotes neoplastic progression in oral squamous cell carcinoma
H Alam, AV Bhate, P Gangadaran, SS Sawant, S Salot, L Sehgal, ...
BMC cancer 12 (1), 1-15, 2012
722012
Plakophilin3 loss leads to an increase in PRL3 levels promoting K8 dephosphorylation, which is required for transformation and metastasis
N Khapare, ST Kundu, L Sehgal, M Sawant, R Priya, P Gosavi, N Gupta, ...
PloS one 7 (6), e38561, 2012
622012
Loss of keratins 8 and 18 leads to alterations in α6β4-integrin-mediated signalling and decreased neoplastic progression in an oral-tumour-derived cell line
H Alam, ST Kundu, SN Dalal, MM Vaidya
Journal of cell science 124 (12), 2096-2106, 2011
532011
MLL4 is required to maintain broad H3K4me3 peaks and super-enhancers at tumor suppressor genes
SS Dhar, D Zhao, T Lin, B Gu, K Pal, SJ Wu, H Alam, J Lv, K Yun, ...
Molecular cell 70 (5), 825-841. e6, 2018
522018
Understanding the role of keratins 8 and 18 in neoplastic potential of breast cancer derived cell lines
SV Iyer, PP Dange, H Alam, SS Sawant, AD Ingle, AM Borges, NV Shirsat, ...
PloS one 8 (1), e53532, 2013
512013
Transcriptional repression of histone deacetylase 3 by the histone demethylase KDM2A is coupled to tumorigenicity of lung cancer cells
SS Dhar, H Alam, N Li, KW Wagner, J Chung, YW Ahn, MG Lee
Journal of Biological Chemistry 289 (11), 7483-7496, 2014
422014
Clinical significance of aberrant vimentin expression in oral premalignant lesions and carcinomas
SS Sawant, MM Vaidya, DA Chaukar, H Alam, C Dmello, P Gangadaran, ...
Oral diseases 20 (5), 453-465, 2014
392014
Loss of keratin 8 phosphorylation leads to increased tumor progression and correlates with clinico-pathological parameters of OSCC patients
H Alam, P Gangadaran, AV Bhate, DA Chaukar, SS Sawant, R Tiwari, ...
PLoS One 6 (11), e27767, 2011
382011
HP1γ promotes lung adenocarcinoma by downregulating the transcription-repressive regulators NCOR2 and ZBTB7A
H Alam, N Li, SS Dhar, SJ Wu, J Lv, K Chen, ER Flores, L Baseler, ...
Cancer research 78 (14), 3834-3848, 2018
292018
Vimentin regulates differentiation switch via modulation of keratin 14 levels and their expression together correlates with poor prognosis in oral cancer patients
C Dmello, S Sawant, H Alam, P Gangadaran, S Mogre, R Tiwari, ...
PLoS One 12 (2), e0172559, 2017
232017
KMT2D deficiency impairs super-enhancers to confer a glycolytic vulnerability in lung cancer
H Alam, M Tang, M Maitituoheti, SS Dhar, M Kumar, CY Han, CR Ambati, ...
Cancer cell 37 (4), 599-617. e7, 2020
202020
Vimentin-mediated regulation of cell motility through modulation of beta4 integrin protein levels in oral tumor derived cells
C Dmello, S Sawant, H Alam, P Gangadaran, R Tiwari, H Dongre, N Rana, ...
The international journal of biochemistry & cell biology 70, 161-172, 2016
182016
14-3-3γ-Mediated transport of plakoglobin to the cell border is required for the initiation of desmosome assembly in vitro and in vivo
L Sehgal, A Mukhopadhyay, A Rajan, N Khapare, M Sawant, SS Vishal, ...
Journal of cell science 127 (10), 2174-2188, 2014
152014
Keratin 5/14‑mediated cell differentiation and transformation are regulated by TAp63 and Notch‑1 in oral squamous cell carcinoma‑derived cells
SS Srivastava, H Alam, SJ Patil, R Shrinivasan, S Raikundalia, ...
Oncology reports 39 (5), 2393-2401, 2018
82018
Enhancer reprogramming confers dependence on glycolysis and IGF signaling in KMT2D mutant melanoma
M Maitituoheti, EZ Keung, M Tang, L Yan, H Alam, G Han, AK Singh, ...
Cell reports 33 (3), 108293, 2020
32020
Identification of morphological and biochemical changes in keratin‐8/18 knock‐down cells using Raman spectroscopy
SP Singh, H Alam, C Dmello, H Mamgain, MM Vaidya, RR Dasari, ...
Journal of biophotonics 10 (10), 1377-1384, 2017
22017
Raman spectroscopic study of keratin 8 knockdown oral squamous cell carcinoma derived cells
SP Singh, H Alam, C Dmello, MM Vaidya, CM Krishna
Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues X …, 2012
22012
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