Karelle Leroy
Karelle Leroy
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Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits
K Schindowski, A Bretteville, K Leroy, S Bégard, JP Brion, M Hamdane, ...
The American journal of pathology 169 (2), 599-616, 2006
Increased level of active GSK‐3β in Alzheimer’s disease and accumulation in argyrophilic grains and in neurones at different stages of neurofibrillary degeneration
K Leroy, Z Yilmaz, JP Brion
Neuropathology and applied neurobiology 33 (1), 43-55, 2007
Developmental expression and localization of glycogen synthase kinase-3β in rat brain
K Leroy, JP Brion
Journal of chemical neuroanatomy 16 (4), 279-293, 1999
Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation
R Dayanandan, M Van Slegtenhorst, TGA Mack, L Ko, SH Yen, K Leroy, ...
FEBS letters 446 (2-3), 228-232, 1999
Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt–PCP–JNK pathway
R Killick, EM Ribe, R Al-Shawi, B Malik, C Hooper, C Fernandes, ...
Molecular psychiatry 19 (1), 88-98, 2014
The active form of glycogen synthase kinase-3β is associated with granulovacuolar degeneration in neurons in Alzheimer's disease
K Leroy, A Boutajangout, M Authelet, JR Woodgett, BH Anderton, JP Brion
Acta neuropathologica 103 (2), 91-99, 2002
Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase
P Derkinderen, TME Scales, DP Hanger, KY Leung, HL Byers, MA Ward, ...
Journal of Neuroscience 25 (28), 6584-6593, 2005
Hallmarks of Alzheimer’s disease in stem-cell-derived human neurons transplanted into mouse brain
I Espuny-Camacho, AM Arranz, M Fiers, A Snellinx, K Ando, S Munck, ...
Neuron 93 (5), 1066-1081. e8, 2017
Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice
K Leroy, A Bretteville, K Schindowski, E Gilissen, M Authelet, R De Decker, ...
The American journal of pathology 171 (3), 976-992, 2007
Neurofibrillary tangles and tau phosphorylation
C O'Neill, B Anderton, JP Brion, BH Anderton, M Authelet, R Dayanandan, ...
Biochemical Society Symposia 67, 81-88, 2001
Lack of tau proteins rescues neuronal cell death and decreases amyloidogenic processing of APP in APP/PS1 mice
K Leroy, K Ando, V Laporte, R Dedecker, V Suain, M Authelet, C Héraud, ...
The American journal of pathology 181 (6), 1928-1940, 2012
Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice
R Killick, G Scales, K Leroy, M Causevic, C Hooper, EE Irvine, ...
Biochemical and biophysical research communications 386 (1), 257-262, 2009
Sites of phosphorylation in tau and factors affecting their regulation
C O'Neill, B Anderton, BH Anderton, J Betts, WP Blackstock, JP Brion, ...
Biochemical Society Symposia 67, 73-80, 2001
Lithium treatment arrests the development of neurofibrillary tangles in mutant tau transgenic mice with advanced neurofibrillary pathology
K Leroy, K Ando, C Héraud, Z Yilmaz, M Authelet, JM Boeynaems, L Buée, ...
Journal of Alzheimer's Disease 19 (2), 705-719, 2010
Mint2/X11‐like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease
DM McLoughlin, NG Irving, J Brownlees, JP Brion, K Leroy, CCJ Miller
European journal of neuroscience 11 (6), 1988-1994, 1999
Phrenic motor neuron degeneration compromises phrenic axonal circuitry and diaphragm activity in a unilateral cervical contusion model of spinal cord injury
C Nicaise, TJ Hala, DM Frank, JL Parker, M Authelet, K Leroy, JP Brion, ...
Experimental neurology 235 (2), 539-552, 2012
Expression of tau mRNA and soluble tau isoforms in affected and non‐affected brain areas in Alzheimer's disease
A Boutajangout, A Boom, K Leroy, JP Brion
FEBS letters 576 (1-2), 183-189, 2004
Degeneration of phrenic motor neurons induces long-term diaphragm deficits following mid-cervical spinal contusion in mice
C Nicaise, R Putatunda, TJ Hala, KA Regan, DM Frank, JP Brion, K Leroy, ...
Journal of neurotrauma 29 (18), 2748-2760, 2012
Accelerated human mutant tau aggregation by knocking out murine tau in a transgenic mouse model
K Ando, K Leroy, C Héraud, Z Yilmaz, M Authelet, V Suain, R De Decker, ...
The American journal of pathology 178 (2), 803-816, 2011
Amyloid-β pathology enhances pathological fibrillary tau seeding induced by Alzheimer PHF in vivo
C Vergara, S Houben, V Suain, Z Yilmaz, R De Decker, V Vanden Dries, ...
Acta neuropathologica 137 (3), 397-412, 2019
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