| Antibiotics and antibiotic resistance: a bitter fight against evolution A Rodríguez-Rojas, J Rodríguez-Beltrán, A Couce, J Blázquez International Journal of Medical Microbiology 303 (6-7), 293-297, 2013 | 233 | 2013 |
| Antimicrobials as promoters of genetic variation J Blázquez, A Couce, J Rodríguez-Beltrán, A Rodríguez-Rojas Current opinion in microbiology 15 (5), 561-569, 2012 | 155 | 2012 |
| Effect of recA inactivation on mutagenesis of Escherichia coli exposed to sublethal concentrations of antimicrobials TD Thi, E López, A Rodríguez-Rojas, J Rodríguez-Beltrán, A Couce, ... Journal of Antimicrobial Chemotherapy 66 (3), 531-538, 2011 | 119 | 2011 |
| Side effects of antibiotics on genetic variability A Couce, J Blázquez FEMS microbiology reviews 33 (3), 531-538, 2009 | 101 | 2009 |
| The rule of declining adaptability in microbial evolution experiments A Couce, OA Tenaillon Frontiers in genetics 6, 99, 2015 | 65 | 2015 |
| Mutator genomes decay, despite sustained fitness gains, in a long-term experiment with bacteria A Couce, LV Caudwell, C Feinauer, T Hindré, JP Feugeas, M Weigt, ... Proceedings of the National Academy of Sciences 114 (43), E9026-E9035, 2017 | 53 | 2017 |
| Assessing the emergence of resistance: the absence of biological cost in vivo may compromise fosfomycin treatments for P. aeruginosa infections A Rodríguez-Rojas, MD Maciá, A Couce, C Gómez, A Castañeda-García, ... PLoS One 5 (4), e10193, 2010 | 45 | 2010 |
| Genomewide overexpression screen for fosfomycin resistance in Escherichia coli: MurA confers clinical resistance at low fitness cost A Couce, A Briales, A Rodríguez-Rojas, C Costas, Á Pascual, J Blázquez Antimicrobial agents and chemotherapy 56 (5), 2767-2769, 2012 | 44 | 2012 |
| The Escherichia coli SOS gene dinF protects against oxidative stress and bile salts J Rodríguez-Beltrán, A Rodríguez-Rojas, JR Guelfo, A Couce, J Blázquez PloS one 7 (4), e34791, 2012 | 41 | 2012 |
| Bypass of genetic constraints during mutator evolution to antibiotic resistance A Couce, A Rodríguez-Rojas, J Blázquez Proceedings of the Royal Society B: Biological Sciences 282 (1804), 20142698, 2015 | 38 | 2015 |
| Mutational spectrum drives the rise of mutator bacteria A Couce, JR Guelfo, J Blázquez PLoS Genet 9 (1), e1003167, 2013 | 37 | 2013 |
| Frequency of spontaneous resistance to fosfomycin combined with different antibiotics in Pseudomonas aeruginosa A Rodríguez-Rojas, A Couce, J Blázquez Antimicrobial agents and chemotherapy 54 (11), 4948-4949, 2010 | 26 | 2010 |
| Intrapopulation variability in mutator prevalence among urinary tract infection isolates of Escherichia coli A Couce, N Alonso-Rodriguez, C Costas, A Oliver, J Blázquez Clinical Microbiology and Infection 22 (6), 566. e1-566. e7, 2016 | 14 | 2016 |
| Estimating mutation rates in low-replication experiments A Couce, J Blázquez Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 714 (1 …, 2011 | 13 | 2011 |
| Parallel evolution of high-level aminoglycoside resistance in Escherichia coli under low and high mutation supply rates C Ibacache-Quiroga, JC Oliveros, A Couce, J Blázquez Frontiers in microbiology 9, 427, 2018 | 12 | 2018 |
| Determinants of genetic diversity of spontaneous drug resistance in bacteria A Couce, A Rodríguez-Rojas, J Blázquez Genetics 203 (3), 1369-1380, 2016 | 7 | 2016 |
| Flux, toxicity, and expression costs generate complex genetic interactions in a metabolic pathway H Kemble, C Eisenhauer, A Couce, A Chapron, M Magnan, G Gautier, ... Science Advances 6 (23), eabb2236, 2020 | 5* | 2020 |
| Mutation bias and GC content shape antimutator invasions A Couce, O Tenaillon Nature communications 10 (1), 1-9, 2019 | 5* | 2019 |
| Bypass of genetic constraints during mutator evolution to antibiotic resistance (vol 282, 20142698, 2015) A Couce, A Rodriguez-Rojas, J Blazquez PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES 283 (1837), 2016 | | 2016 |
| Clonal expansion and mutational spectrum in the evolution of antibiotic resistance A Couce Biblos-e Archivo, 2012 | | 2012 |
Jesús BlazquezProfesor de investigación, Centro Nacional de BiotecnologíaVerified email at cnb.csic.es
