Knocking down barriers: advances in siRNA delivery KA Whitehead, R Langer, DG Anderson Nature reviews Drug discovery 8 (2), 129-138, 2009 | 3719 | 2009 |
Non-viral vectors for gene-based therapy H Yin, RL Kanasty, AA Eltoukhy, AJ Vegas, JR Dorkin, DG Anderson Nature reviews genetics 15 (8), 541-555, 2014 | 3435 | 2014 |
Physical and mechanical properties of PLA, and their functions in widespread applications—A comprehensive review S Farah, DG Anderson, R Langer Advanced drug delivery reviews 107, 367-392, 2016 | 3218 | 2016 |
Pembrolizumab alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-048): a randomised … B Burtness, KJ Harrington, R Greil, D Soulières, M Tahara, G de Castro, ... The Lancet 394 (10212), 1915-1928, 2019 | 2668 | 2019 |
CRISPR-Cas9 knockin mice for genome editing and cancer modeling RJ Platt, S Chen, Y Zhou, MJ Yim, L Swiech, HR Kempton, JE Dahlman, ... Cell 159 (2), 440-455, 2014 | 2119 | 2014 |
Delivery materials for siRNA therapeutics R Kanasty, JR Dorkin, A Vegas, D Anderson Nature materials 12 (11), 967-977, 2013 | 2091 | 2013 |
A combinatorial library of lipid-like materials for delivery of RNAi therapeutics A Akinc, A Zumbuehl, M Goldberg, ES Leshchiner, V Busini, N Hossain, ... Nature biotechnology 26 (5), 561-569, 2008 | 1469 | 2008 |
Treating metastatic cancer with nanotechnology A Schroeder, DA Heller, MM Winslow, JE Dahlman, GW Pratt, R Langer, ... Nature Reviews Cancer 12 (1), 39-50, 2012 | 1303 | 2012 |
Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery H Lee, AKR Lytton-Jean, Y Chen, KT Love, AI Park, ED Karagiannis, ... Nature nanotechnology 7 (6), 389-393, 2012 | 1247 | 2012 |
Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype H Yin, W Xue, S Chen, RL Bogorad, E Benedetti, M Grompe, ... Nature biotechnology 32 (6), 551-553, 2014 | 1232 | 2014 |
Lipid-like materials for low-dose, in vivo gene silencing KT Love, KP Mahon, CG Levins, KA Whitehead, W Querbes, JR Dorkin, ... Proceedings of the National Academy of Sciences 107 (5), 1864-1869, 2010 | 1120 | 2010 |
Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo H Yin, CQ Song, JR Dorkin, LJ Zhu, Y Li, Q Wu, A Park, J Yang, S Suresh, ... Nature biotechnology 34 (3), 328-333, 2016 | 987 | 2016 |
Delivering the messenger: advances in technologies for therapeutic mRNA delivery PS Kowalski, A Rudra, L Miao, DG Anderson Molecular Therapy 27 (4), 710-728, 2019 | 973 | 2019 |
CRISPR-mediated direct mutation of cancer genes in the mouse liver W Xue, S Chen, H Yin, T Tammela, T Papagiannakopoulos, NS Joshi, ... Nature 514 (7522), 380-384, 2014 | 911 | 2014 |
Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells DG Anderson, S Levenberg, R Langer Nature biotechnology 22 (7), 863-866, 2004 | 905 | 2004 |
Size-and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates O Veiseh, JC Doloff, M Ma, AJ Vegas, HH Tam, AR Bader, J Li, E Langan, ... Nature materials 14 (6), 643-651, 2015 | 901 | 2015 |
Therapeutic siRNA silencing in inflammatory monocytes in mice F Leuschner, P Dutta, R Gorbatov, TI Novobrantseva, JS Donahoe, ... Nature biotechnology 29 (11), 1005-1010, 2011 | 892 | 2011 |
Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling G Sahay, W Querbes, C Alabi, A Eltoukhy, S Sarkar, C Zurenko, ... Nature biotechnology 31 (7), 653-658, 2013 | 887 | 2013 |
Bio-inspired polymer composite actuator and generator driven by water gradients M Ma, L Guo, DG Anderson, R Langer Science 339 (6116), 186-189, 2013 | 865 | 2013 |
Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties CP Larsen, TC Pearson, AB Adams, P Tso, N Shirasugi, E Strobertb, ... American Journal of Transplantation 5 (3), 443-453, 2005 | 820 | 2005 |