Continuous flow α-trifluoromethylation of ketones by metal-free visible light photoredox catalysis D Cantillo, O de Frutos, JA Rincon, C Mateos, CO Kappe Organic letters 16 (3), 896-899, 2014 | 165 | 2014 |
Metallaphotoredox-Catalyzed Cross-Electrophile Csp3–Csp3 Coupling of Aliphatic Bromides RT Smith, X Zhang, JA Rincón, J Agejas, C Mateos, M Barberis, ... Journal of the American Chemical Society 140 (50), 17433-17438, 2018 | 157 | 2018 |
Automated platforms for reaction self-optimization in flow C Mateos, MJ Nieves-Remacha, JA Rincón Reaction Chemistry & Engineering 4 (9), 1536-1544, 2019 | 122 | 2019 |
Straightforward strategies for the preparation of NH-sulfoximines: a serendipitous story JA Bull, L Degennaro, R Luisi Synlett 28 (19), 2525-2538, 2017 | 122 | 2017 |
A scalable procedure for light-induced benzylic brominations in continuous flow D Cantillo, O de Frutos, JA Rincon, C Mateos, CO Kappe The Journal of Organic Chemistry 79 (1), 223-229, 2014 | 118 | 2014 |
A continuous-flow protocol for light-induced benzylic fluorinations D Cantillo, O de Frutos, JA Rincon, C Mateos, CO Kappe The Journal of Organic Chemistry 79 (17), 8486-8490, 2014 | 105 | 2014 |
Preparation, Use, and Safety of O-Mesitylenesulfonylhydroxylamine J Mendiola, JA Rincón, C Mateos, JF Soriano, Ó de Frutos, JK Niemeier, ... Organic process research & development 13 (2), 263-267, 2009 | 105 | 2009 |
Regioselective palladium-catalyzed arylation of 4-chloropyrazoles C Mateos, J Mendiola, M Carpintero, JM Mínguez Organic Letters 12 (21), 4924-4927, 2010 | 68 | 2010 |
Finding the perfect match: a combined computational and experimental study toward efficient and scalable photosensitized [2+ 2] cycloadditions in flow JD Williams, M Nakano, R Gérardy, JA Rincón, O De Frutos, C Mateos, ... Organic Process Research & Development 23 (1), 78-87, 2018 | 67 | 2018 |
Decatungstate‐Mediated C(sp3)–H Heteroarylation via Radical‐Polar Crossover in Batch and Flow T Wan, L Capaldo, G Laudadio, AV Nyuchev, JA Rincón, ... Angewandte Chemie International Edition 60 (33), 17893-17897, 2021 | 63 | 2021 |
Discovery of a Novel Series of Orally Active Nociceptin/Orphanin FQ (NOP) Receptor Antagonists Based on a Dihydrospiro(piperidine-4,7′-thieno[2,3-c]pyran … MA Toledo, C Pedregal, C Lafuente, N Diaz, MA Martinez-Grau, ... Journal of medicinal chemistry 57 (8), 3418-3429, 2014 | 59 | 2014 |
Electrochemical Deprotection of para-Methoxybenzyl Ethers in a Flow Electrolysis Cell RA Green, KE Jolley, AAM Al-Hadedi, D Pletcher, DC Harrowven, ... Organic letters 19 (8), 2050-2053, 2017 | 57 | 2017 |
Rapid optimization of photoredox reactions for continuous-flow systems using microscale batch technology M González-Esguevillas, DF Fernández, JA Rincón, M Barberis, ... ACS Central Science 7 (7), 1126-1134, 2021 | 56 | 2021 |
Light‐Induced C H Arylation of (Hetero) arenes by In Situ Generated Diazo Anhydrides D Cantillo, C Mateos, JA Rincon, O de Frutos, CO Kappe Chemistry–A European Journal 21 (37), 12894-12898, 2015 | 56 | 2015 |
Continuous photochemical benzylic bromination using in situ generated Br 2: process intensification towards optimal PMI and throughput A Steiner, JD Williams, O De Frutos, JA Rincón, C Mateos, CO Kappe Green chemistry 22 (2), 448-454, 2020 | 54 | 2020 |
A Concise and Convergent Route to 5, 8-Disubstituted Indolizidine and 1, 4-Disubstituted Quinolizidine Ring Cores by Diastereoselective Aza-Diels− Alder Reaction J Barluenga, C Mateos, F Aznar, C Valdés Organic Letters 4 (11), 1971-1974, 2002 | 45 | 2002 |
Accelerated and Scalable C(sp3)–H Amination via Decatungstate Photocatalysis Using a Flow Photoreactor Equipped with High-Intensity LEDs T Wan, Z Wen, G Laudadio, L Capaldo, R Lammers, JA Rincón, ... ACS Central Science 8 (1), 51-56, 2021 | 42 | 2021 |
Green and scalable procedure for extremely fast ligandless Suzuki–Miyaura cross-coupling reactions in aqueous IPA using solid-supported Pd in continuous flow C Mateos, JA Rincón, B Martín-Hidalgo, J Villanueva Tetrahedron letters 55 (27), 3701-3705, 2014 | 40 | 2014 |
Fast continuous alcohol amination employing a hydrogen borrowing protocol R Labes, C Mateos, C Battilocchio, Y Chen, P Dingwall, GR Cumming, ... Green chemistry 21 (1), 59-63, 2019 | 38 | 2019 |
Synthesis of enantiopure unnatural amino acids by metallaphotoredox catalysis TM Faraggi, C Rouget-Virbel, JA Rincón, M Barberis, C Mateos, ... Organic process research & development 25 (8), 1966-1973, 2021 | 34 | 2021 |