| Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma JL Kopp, G von Figura, E Mayes, FF Liu, CL Dubois, JP Morris, FC Pan, ... Cancer cell 22 (6), 737-750, 2012 | 741 | 2012 |
| Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas JL Kopp, CL Dubois, AE Schaffer, E Hao, HP Shih, PA Seymour, J Ma, ... Development 138 (4), 653-665, 2011 | 534 | 2011 |
| Hybrid periportal hepatocytes regenerate the injured liver without giving rise to cancer J Font-Burgada, S Shalapour, S Ramaswamy, B Hsueh, D Rossell, ... Cell 162 (4), 766-779, 2015 | 465 | 2015 |
| Small increases in the level of Sox2 trigger the differentiation of mouse embryonic stem cells JL Kopp, BD Ormsbee, M Desler, A Rizzino Stem cells 26 (4), 903-911, 2008 | 443 | 2008 |
| Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells R Carpentier, RE Suñer, N Van Hul, JL Kopp, JB Beaudry, S Cordi, ... Gastroenterology 141 (4), 1432-1438. e4, 2011 | 290 | 2011 |
| Sox9 plays multiple roles in the lung epithelium during branching morphogenesis BE Rockich, SM Hrycaj, HP Shih, MS Nagy, MAH Ferguson, JL Kopp, ... Proceedings of the National Academy of Sciences 110 (47), E4456-E4464, 2013 | 273 | 2013 |
| Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice C Dorrell, L Erker, J Schug, JL Kopp, PS Canaday, AJ Fox, O Smirnova, ... Genes & development 25 (11), 1193-1203, 2011 | 270 | 2011 |
| A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation HP Shih, JL Kopp, M Sandhu, CL Dubois, PA Seymour, A Grapin-Botton, ... Development 139 (14), 2488-2499, 2012 | 268 | 2012 |
| Stem cells versus plasticity in liver and pancreas regeneration JL Kopp, M Grompe, M Sander Nature cell biology 18 (3), 238-245, 2016 | 186 | 2016 |
| Elevating the levels of Sox2 in embryonal carcinoma cells and embryonic stem cells inhibits the expression of Sox2: Oct-3/4 target genes B Boer, J Kopp, S Mallanna, M Desler, H Chakravarthy, PJ Wilder, ... Nucleic acids research 35 (6), 1773-1786, 2007 | 160 | 2007 |
| Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors MG De Vas, JL Kopp, C Heliot, M Sander, S Cereghini, C Haumaitre Development 142 (5), 871-882, 2015 | 149 | 2015 |
| Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma RG Fox, NK Lytle, DV Jaquish, FD Park, T Ito, J Bajaj, CS Koechlein, ... Nature 534 (7607), 407-411, 2016 | 140 | 2016 |
| Hyperinsulinemia in obesity, inflammation, and cancer AMY Zhang, EA Wellberg, JL Kopp, JD Johnson Diabetes & metabolism journal 45 (3), 285, 2021 | 136 | 2021 |
| Cell of origin affects tumour development and phenotype in pancreatic ductal adenocarcinoma AYL Lee, CL Dubois, K Sarai, S Zarei, DF Schaeffer, M Sander, JL Kopp Gut 68 (3), 487-498, 2019 | 122 | 2019 |
| Progenitor cell domains in the developing and adult pancreas JL Kopp, CL Dubois, E Hao, F Thorel, PL Herrera, M Sander Cell cycle 10 (12), 1921-1927, 2011 | 99 | 2011 |
| Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration FJ Barrionuevo, A Hurtado, GJ Kim, FM Real, M Bakkali, JL Kopp, ... Elife 5, e15635, 2016 | 85 | 2016 |
| Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell of origin E Espinet, Z Gu, CD Imbusch, NA Giese, M Büscher, M Safavi, ... Cancer discovery 11 (3), 638-659, 2021 | 79 | 2021 |
| Loss of Pten and activation of Kras synergistically induce formation of intraductal papillary mucinous neoplasia from pancreatic ductal cells in mice JL Kopp, CL Dubois, DF Schaeffer, A Samani, F Taghizadeh, RW Cowan, ... Gastroenterology 154 (5), 1509-1523. e5, 2018 | 70 | 2018 |
| Endogenous hyperinsulinemia contributes to pancreatic cancer development AMY Zhang, J Magrill, TJJ de Winter, X Hu, S Skovsø, DF Schaeffer, ... Cell metabolism 30 (3), 403-404, 2019 | 67 | 2019 |
| Unique and selective effects of five Ets family members, Elf3, Ets1, Ets2, PEA3, and PU. 1, on the promoter of the type II transforming growth factor-β receptor gene JL Kopp, PJ Wilder, M Desler, JH Kim, J Hou, T Nowling, A Rizzino Journal of Biological Chemistry 279 (19), 19407-19420, 2004 | 59 | 2004 |
Hung Ping ShihCity of HopeDirección de correo verificada de coh.org
