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Noé Seija
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AID in antibody diversification: there and back again
Y Feng, N Seija, JM Di Noia, A Martin
Trends in immunology 41 (7), 586-600, 2020
1262020
S100-A9 protein in exosomes from chronic lymphocytic leukemia cells promotes NF-κB activity during disease progression
D Prieto, N Sotelo, N Seija, S Sernbo, C Abreu, R Durán, M Gil, E Sicco, ...
Blood, The Journal of the American Society of Hematology 130 (6), 777-788, 2017
942017
FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation
Y Feng, C Li, JA Stewart, P Barbulescu, N Seija Desivo, A Álvarez-Quilón, ...
Nature 600 (7888), 324-328, 2021
322021
Ibrutinib therapy downregulates AID enzyme and proliferative fractions in chronic lymphocytic leukemia
PE Morande, M Sivina, A Uriepero, N Seija, C Berca, P Fresia, AI Landoni, ...
Blood, The Journal of the American Society of Hematology 133 (19), 2056-2068, 2019
192019
AID overexpression leads to aggressive murine CLL and nonimmunoglobulin mutations that mirror human neoplasms
PE Morande, XJ Yan, J Sepulveda, N Seija, ME Marquez, N Sotelo, ...
Blood, The Journal of the American Society of Hematology 138 (3), 246-258, 2021
132021
LPL protein in chronic lymphocytic leukaemia have different origins in mutated and unmutated patients. Advances for a new prognostic marker in CLL
D Prieto, N Seija, A Uriepero, T Souto‐Padron, C Oliver, V Irigoin, ...
British journal of haematology 182 (4), 521-525, 2018
122018
AFF3, a susceptibility factor for autoimmune diseases, is a molecular facilitator of immunoglobulin class switch recombination
S Tsukumo, PG Subramani, N Seija, M Tabata, Y Maekawa, Y Mori, ...
Science Advances 8 (34), eabq0008, 2022
82022
Immunoregulatory effects of Lurbinectedin in chronic lymphocytic leukemia
D Risnik, A Colado, E Podaza, MB Almejún, EE Elías, RF Bezares, ...
Cancer Immunology, Immunotherapy 69, 813-824, 2020
72020
The Antigen Receptor as a Driver of B-Cell Lymphoma Development and Evolution
J Sepulveda, N Seija, P Oppezzo, MA Navarrete
Hematology- Latest Research and Clinical Advances, 2017
32017
Analyzing the mutational landscape of two CLL mouse models overexpressing AID identifies proliferative fraction-associated tumor genes involved in leukemic development and …
P Morande, J Yan, J Sepulveda, N Seija, M Crispo, N Rego, D Robbiani, ...
LEUKEMIA & LYMPHOMA 61, 133-134, 2020
12020
Implicancias de la enzima AID en la mutagénesis y evolución clonal durante la progresión de la Leucemia Linfoide Crónica
N Seija
Udelar. FC., 2018
12018
B-cell intrinsic regulation of antibody mediated immunity by histone H2A deubiquitinase BAP1
Y Liang, HC Wang, N Seija, YH Lin, LT Tung, JM Di Noia, D Langlais, ...
Frontiers in Immunology 15, 1353138, 2024
2024
DOT1L limits RNAPII promoter-proximal pause release thus enabling Activation Induced Deaminase activity genome-wide
PG Subramani, N Seija, J Ridani, J Boulais, P Donnelly, M Provencher, ...
2023
Ibrutinib therapy downregulates AID enzyme and proliferative fractions in chronic lymphocytic leukemia
P Morande, M Sivina, A Uriepero, N Seija, C Berca, P Fresia, AI Landoni, ...
LEUKEMIA & LYMPHOMA 61, 130-132, 2020
2020
Desenmarañando la progresión de la LLC en pacientes no mutados:: relación entre la expresión funcional de la citidina deaminasa inducida por activación con la evolución de la …
N Seija, J Sepulveda, D Prieto, P Morande, A Uriepero, M Navarrete, ...
Revista Hematología 22 (2), 33-35, 2018
2018
Unraveling CLL progression in unmutated patients: linking functional AID expression with disease evolution
P Oppezzo, N Seija, D Prieto, J Sepulveda, P Morande, A Uriepero, ...
LEUKEMIA & LYMPHOMA 58, 207-208, 2017
2017
AID and LPL mRNA expression identify patients with different clinical outcomes within UM CLLs
P Oppezzo, A Ines Landoni, V Irigoin, C Oliver, V Remedi, G Borelli, ...
LEUKEMIA & LYMPHOMA 58, 202-203, 2017
2017
GIMAP5 protein is over expressed in CLL proliferative subsets and linked with cell death inhibition
P Oppezzo, C Abreu, D Prieto, C Ortega, F Palacios, N Seija, G Greif, ...
LEUKEMIA & LYMPHOMA 58, 98-99, 2017
2017
Proteomic characterization of CLL plasma exosomes during disease evolution identify S100-A9 protein as a key molecule in the activation of the canonical NF-kB pathway
P Oppezzo, D Prieto, N Seija, N Sotelo, C Abreu, C Ortega, R Duran, ...
LEUKEMIA & LYMPHOMA 58, 90-90, 2017
2017
Constitutive aid expression in CLL mouse model leads to disease progression, tumor proliferation and diminished survival
P Morande, XJ Yan, N Sotelo, D Prieto, N Seija, M Crispo, N Chiorazzi, ...
LEUKEMIA & LYMPHOMA 56, 74-74, 2015
2015
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