| Whole-genome sequence variation, population structure and demographic history of the Dutch population Nature genetics 46 (8), 818-825, 2014 | 708 | 2014 |
| The Genome of the Netherlands: design, and project goals DI Boomsma, C Wijmenga, EP Slagboom, MA Swertz, LC Karssen, ... European journal of human genetics 22 (2), 221-227, 2014 | 324 | 2014 |
| Integrator complex regulates NELF-mediated RNA polymerase II pause/release and processivity at coding genes Stadelmayer, Koval, Benkirane Nat Commun 5, 2014 | 159 | 2014 |
| Characteristics of de novo structural changes in the human genome WP Kloosterman, LC Francioli, V Koval, P Arp, LC Karssen, BP Coe, ... Genome research, gr. 185041.114, 2015 | 151 | 2015 |
| Improved imputation quality of low-frequency and rare variants in European samples using the ‘Genome of The Netherlands’ P Deelen, A Menelaou, EM Van Leeuwen, A Kanterakis, F Van Dijk, ... European Journal of Human Genetics 22 (11), 1321-1326, 2014 | 121 | 2014 |
| A high-quality human reference panel reveals the complexity and distribution of genomic structural variants JY Hehir-Kwa, T Marschall, WP Kloosterman, LC Francioli, JA Baaijens, ... Nature communications 7 (1), 1-10, 2016 | 104 | 2016 |
| Population-specific genotype imputations using minimac or IMPUTE2 EM Van Leeuwen, A Kanterakis, P Deelen, MV Kattenberg, PE Slagboom, ... Nature protocols 10 (9), 1285-1296, 2015 | 97 | 2015 |
| Deleterious alleles in the human genome are on average younger than neutral alleles of the same frequency A Kiezun, SL Pulit, LC Francioli, F van Dijk, M Swertz, DI Boomsma, ... PLoS genetics 9 (2), e1003301, 2013 | 72 | 2013 |
| Exploring the inflammatory metabolomic profile to predict response to TNF-α inhibitors in rheumatoid arthritis BVJ Cuppen, J Fu, HA Van Wietmarschen, AC Harms, S Koval, ... PloS one 11 (9), e0163087, 2016 | 56 | 2016 |
| Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels EM Van Leeuwen, LC Karssen, J Deelen, A Isaacs, C Medina-Gomez, ... Nature communications 6 (1), 6065, 2015 | 51 | 2015 |
| Integrated clinical and omics approach to rare diseases: novel genes and oligogenic inheritance in holoprosencephaly A Kim, C Savary, C Dubourg, W Carré, C Mouden, H Hamdi-Roze, ... Brain 142 (1), 35-49, 2019 | 47 | 2019 |
| Role of amino acids in rheumatoid arthritis studied by metabolomics M He, AC Harms, E van Wijk, M Wang, R Berger, S Koval, T Hankemeier, ... International journal of rheumatic diseases 22 (1), 38-46, 2019 | 33 | 2019 |
| Effects of growth altitude on chemical constituents and delayed luminescence properties in medicinal rhubarb M Sun, L Li, M Wang, E Van Wijk, M He, R Van Wijk, S Koval, ... Journal of Photochemistry and Photobiology B: Biology 162, 24-33, 2016 | 30 | 2016 |
| A framework for the detection of de novo mutations in family-based sequencing data LC Francioli, M Cretu-Stancu, KV Garimella, M Fromer, WP Kloosterman, ... European Journal of Human Genetics 25 (2), 227-233, 2017 | 29 | 2017 |
| Tracking biochemical changes correlated with ultra-weak photon emission using metabolomics RCR Burgos, K Červinková, T van der Laan, R Ramautar, EPA van Wijk, ... Journal of Photochemistry and Photobiology B: Biology 163, 237-245, 2016 | 25 | 2016 |
| Spontaneous ultra-weak photon emission in correlation to inflammatory metabolism and oxidative stress in a mouse model of collagen-induced arthritis M He, E van Wijk, H van Wietmarschen, M Wang, M Sun, S Koval, ... Journal of Photochemistry and photobiology B: Biology 168, 98-106, 2017 | 23 | 2017 |
| Measuring ultra-weak photon emission as a non-invasive diagnostic tool for detecting early-stage type 2 diabetes: a step toward personalized medicine M Sun, E Van Wijk, S Koval, R Van Wijk, M He, M Wang, T Hankemeier, ... Journal of Photochemistry and Photobiology B: Biology 166, 86-93, 2017 | 23 | 2017 |
| Long-range percolation on the hierarchical lattice V Koval, R Meester, P Trapman | 19 | 2012 |
| Differences between serum polar lipid profiles of male and female rheumatoid arthritis patients in response to glucocorticoid treatment J Fu, BVJ Cuppen, PMJ Welsing, H van Wietmarschen, AC Harms, ... Inflammopharmacology 24, 397-402, 2016 | 15 | 2016 |
| Traditional Chinese medicine-based subtyping of early-stage type 2 diabetes using plasma metabolomics combined with ultra-weak photon emission M He, M Sun, S Koval, R Van Wijk, T Hankemeier, J Van der Greef, ... Engineering 5 (5), 916-923, 2019 | 13 | 2019 |
Thomas HankemeierProfessor of Analytical Biosciences, Leiden UniversityCorreu electrònic verificat a lacdr.leidenuniv.nl
