| The chemotherapeutic agent DMXAA potently and specifically activates the TBK1–IRF-3 signaling axis ZJ Roberts, N Goutagny, PY Perera, H Kato, H Kumar, T Kawai, S Akira, ... The Journal of experimental medicine 204 (7), 1559-1569, 2007 | 180 | 2007 |
| Induction of endothelial cell apoptosis by the antivascular agent 5, 6-dimethylxanthenone-4-acetic acid LM Ching, Z Cao, C Kieda, S Zwain, MB Jameson, BC Baguley British journal of cancer 86 (12), 1937-1942, 2002 | 154 | 2002 |
| Non-invasive biomarkers for early detection of breast cancer J Li, X Guan, Z Fan, LM Ching, Y Li, X Wang, WM Cao, DX Liu Cancers 12 (10), 2767, 2020 | 151 | 2020 |
| Activation of Tumor-Associated Macrophages by the Vascular Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid Induces an Effective CD8+ T-Cell–Mediated … AS Jassar, E Suzuki, V Kapoor, J Sun, MB Silverberg, L Cheung, ... Cancer research 65 (24), 11752-11761, 2005 | 149 | 2005 |
| Tumor-dependent increased plasma nitrate concentrations as an indication of the antitumor effect of flavone-8-acetic acid and analogues in mice LL Thomsen, LM Ching, L Zhuang, JB Gavin, BC Baguley Cancer Research 51 (1), 77-81, 1991 | 139 | 1991 |
| Induction of tumour necrosis factor-α by single and repeated doses of the antitumour agent 5, 6-dimethylxanthenone-4-acetic acid M Philpott, BC Baguley, LM Ching Cancer chemotherapy and pharmacology 36 (2), 143-148, 1995 | 125 | 1995 |
| Induction of intratumoral tumor necrosis factor (TNF) synthesis and hemorrhagic necrosis by 5, 6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF knockout mice LM Ching, D Goldsmith, WR Joseph, H Körner, JD Sedgwick, ... Cancer research 59 (14), 3304-3307, 1999 | 123 | 1999 |
| Anti-cancer composition comprising DMXAA or related compound BC Baguley, LM Ching, P Kestell, L Zhao US Patent 7,585,893, 2009 | 122 | 2009 |
| Cancer treatment by combination therapy BC Baguley, LM Ching, M Philpott US Patent 7,510,830, 2009 | 122 | 2009 |
| Anti-cancer combinations LS Wang, JW Paxton, LM Ching, BC Baguley, P Kestell US Patent 7,462,642, 2008 | 122 | 2008 |
| Evidence for the production of nitric oxide by activated macrophages treated with the antitumor agents flavone-8-acetic acid and xanthenone-4-acetic acid LL Thomsen, LM Ching, BC Baguley Cancer research 50 (21), 6966-6970, 1990 | 120 | 1990 |
| Induction of natural killer cell activity by the antitumour compound flavone acetic acid (NSC 347 512) LM Ching, BC Baguley European Journal of Cancer and Clinical Oncology 23 (7), 1047-1050, 1987 | 118 | 1987 |
| Stimulation of Tumors to Synthesize Tumor Necrosis Factor-α in Situ Using 5,6-Dimethylxanthenone-4-acetic Acid: A Novel Approach to Cancer Therapy WR Joseph, Z Cao, KG Mountjoy, ES Marshall, BC Baguley, LM Ching Cancer research 59 (3), 633-638, 1999 | 108 | 1999 |
| Relationship between tumour endothelial cell apoptosis and tumour blood flow shutdown following treatment with the antivascular agent DMXAA in mice LM Ching, S Zwain, BC Baguley British journal of cancer 90 (4), 906-910, 2004 | 99 | 2004 |
| The antitumour activity of 5, 6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF receptor-1 knockout mice L Zhao, LM Ching, P Kestell, BC Baguley British journal of cancer 87 (4), 465-470, 2002 | 89 | 2002 |
| Thalidomide pharmacokinetics and metabolite formation in mice, rabbits, and multiple myeloma patients F Chung, J Lu, BD Palmer, P Kestell, P Browett, BC Baguley, M Tingle, ... Clinical cancer research 10 (17), 5949-5956, 2004 | 84 | 2004 |
| Induction of Tumor Necrosis Factor-β Messenger RNA in Human and Murine Cells by the Flavone Acetic Acid Analogue 5,6-Dimethylxanthenone-4-acetic Acid … LM Ching, WR Joseph, KE Crosier, BC Baguley Cancer research 54 (4), 870-872, 1994 | 84 | 1994 |
| Effect of thalidomide on tumour necrosis factor production and anti-tumour activity induced by 5, 6-dimethylxanthenone-4-acetic acid LM Ching, ZF Xu, BH Gummer, BD Palmer, WR Joseph, BC Baguley British journal of cancer 72 (2), 339-343, 1995 | 83 | 1995 |
| DMXAA: an antivascular agent with multiple host responses BC Baguley, LM Ching International Journal of Radiation Oncology* Biology* Physics 54 (5), 1503-1511, 2002 | 80 | 2002 |
| Mechanisms of tumor vascular shutdown induced by 5, 6‐dimethylxanthenone‐4‐acetic acid (DMXAA): increased tumor vascular permeability L Zhao, LM Ching, P Kestell, LR Kelland, BC Baguley International journal of cancer 116 (2), 322-326, 2005 | 77 | 2005 |
