WNT signalling pathways as therapeutic targets in cancer JN Anastas, RT Moon Nature Reviews Cancer 13 (1), 11-26, 2013 | 2160 | 2013 |
Mesenchymal stromal cell exosomes ameliorate experimental bronchopulmonary dysplasia and restore lung function through macrophage immunomodulation GR Willis, A Fernandez-Gonzalez, J Anastas, SH Vitali, X Liu, M Ericsson, ... American journal of respiratory and critical care medicine 197 (1), 104-116, 2018 | 526 | 2018 |
WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors JN Anastas, RM Kulikauskas, T Tamir, H Rizos, GV Long, EM Von Euw, ... The Journal of clinical investigation 124 (7), 2877-2890, 2014 | 216 | 2014 |
New regulators of Wnt/β-catenin signaling revealed by integrative molecular screening MB Major, BS Roberts, JD Berndt, S Marine, J Anastas, N Chung, ... Science signaling 1 (45), ra12-ra12, 2008 | 165 | 2008 |
A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression JN Anastas, TL Biechele, M Robitaille, J Muster, KH Allison, S Angers, ... Oncogene 31 (32), 3696-3708, 2012 | 144 | 2012 |
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG JN Anastas, BM Zee, JH Kalin, M Kim, R Guo, S Alexandrescu, MA Blanco, ... Cancer cell 36 (5), 528-544. e10, 2019 | 138 | 2019 |
Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling JD Berndt, A Aoyagi, P Yang, JN Anastas, L Tang, RT Moon Journal of Cell Biology 194 (5), 737-750, 2011 | 113 | 2011 |
Histone lysine demethylase inhibitors A Jambhekar, JN Anastas, Y Shi Cold Spring Harbor perspectives in medicine 7 (1), a026484, 2017 | 70 | 2017 |
WLS inhibits melanoma cell proliferation through the β‐catenin signalling pathway and induces spontaneous metastasis PT Yang, JN Anastas, RA Toroni, MM Shinohara, JM Goodson, ... EMBO molecular medicine 4 (12), 1294-1307, 2012 | 37 | 2012 |
Functional crosstalk between WNT signaling and tyrosine kinase signaling in cancer JN Anastas Seminars in oncology 42 (6), 820-831, 2015 | 26 | 2015 |
BAF complex maintains glioma stem cells in pediatric H3K27M glioma E Panditharatna, JG Marques, T Wang, MC Trissal, I Liu, L Jiang, A Beck, ... Cancer discovery 12 (12), 2880-2905, 2022 | 25 | 2022 |
RACK7 recognizes H3. 3G34R mutation to suppress expression of MHC class II complex components and their delivery pathway in pediatric glioblastoma F Jiao, Z Li, C He, W Xu, G Yang, T Liu, H Shen, J Cai, JN Anastas, Y Mao, ... Science Advances 6 (29), eaba2113, 2020 | 24 | 2020 |
Histone serotonylation: can the brain have “happy” chromatin? JN Anastas, Y Shi Molecular cell 74 (3), 418-420, 2019 | 20 | 2019 |
Mesenchymal stromal cell therapy for respiratory complications of extreme prematurity B Thébaud American Journal of Perinatology 35 (06), 566-569, 2018 | 11 | 2018 |
A road map for the treatment of pediatric diffuse midline glioma C Koschmann, WN Al-Holou, MM Alonso, J Anastas, P Bandopadhayay, ... Cancer cell 42 (1), 1-5, 2024 | 2 | 2024 |
Applying single cell multi-omic analyses to understand treatment resistance in pediatric high grade glioma RL Murdaugh, JN Anastas Frontiers in Pharmacology 14, 1002296, 2023 | 1 | 2023 |
Wnt Signaling in Melanoma JN Anastas, AJ Chien Wnt Signaling in Development and Disease: Molecular Mechanisms and …, 2014 | 1 | 2014 |
SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells L Zhang, JI Hsu, ED Braekeleer, CW Chen, TD Patel, AG Martell, ... bioRxiv, 2023 | | 2023 |
DIPG-45. ELONGIN B REGULATES H3K27M CHROMATIN INCORPORATION TO PROMOTE MALIGNANCY IN DIFFUSE MIDLINE GLIOMA J Anastas, A Kebede, A Jiao, C Mimoso, R Murdaugh, B Zee, M Filbin, ... Neuro-Oncology 25 (Suppl 1), i23, 2023 | | 2023 |
DIPG-19. BAF COMPLEX PERTURBATION AS A NOVEL THERAPEUTIC OPPORTUNITY IN H3K27M PEDIATRIC GLIOMA E Panditharatna, JG Marques, T Wang, M Trissal, I Liu, L Jiang, A Beck, ... Neuro-Oncology 25 (Supplement_1), i16-i17, 2023 | | 2023 |